SARS-CoV-2 mRNA vaccine design enabled by prototype pathogen preparedness KS Corbett, DK Edwards, SR Leist, OM Abiona, S Boyoglu-Barnum, ... Nature 586 (7830), 567-571, 2020 | 1631 | 2020 |
Evaluation of the mRNA-1273 vaccine against SARS-CoV-2 in nonhuman primates KS Corbett, B Flynn, KE Foulds, JR Francica, S Boyoglu-Barnum, ... New England Journal of Medicine 383 (16), 1544-1555, 2020 | 1238 | 2020 |
A proof of concept for structure-based vaccine design targeting RSV in humans MC Crank, TJ Ruckwardt, M Chen, KM Morabito, E Phung, PJ Costner, ... Science 365 (6452), 505-509, 2019 | 313 | 2019 |
Respiratory syncytial virus prevention within reach: the vaccine and monoclonal antibody landscape NI Mazur, J Terstappen, R Baral, A Bardají, P Beutels, UJ Buchholz, ... The Lancet Infectious Diseases 23 (1), e2-e21, 2023 | 311 | 2023 |
Ultrapotent antibodies against diverse and highly transmissible SARS-CoV-2 variants L Wang, T Zhou, Y Zhang, ES Yang, CA Schramm, W Shi, A Pegu, ... Science 373 (6556), eabh1766, 2021 | 203 | 2021 |
Vaccination with tat toxoid attenuates disease in simian/HIV-challenged macaques CD Pauza, P Trivedi, M Wallace, TJ Ruckwardt, H Le Buanec, W Lu, ... Proceedings of the National Academy of Sciences 97 (7), 3515-3519, 2000 | 199 | 2000 |
Regulatory T Cells Promote Early Influx of CD8+ T Cells in the Lungs of Respiratory Syncytial Virus-Infected Mice and Diminish Immunodominance Disparities TJ Ruckwardt, KL Bonaparte, MC Nason, BS Graham Journal of virology 83 (7), 3019-3028, 2009 | 173 | 2009 |
Immunological lessons from respiratory syncytial virus vaccine development TJ Ruckwardt, KM Morabito, BS Graham Immunity 51 (3), 429-442, 2019 | 157 | 2019 |
Monocytes Treated with Human Immunodeficiency Virus Tat Kill Uninfected CD4+ Cells by a Tumor Necrosis Factor-Related Apoptosis-Induced Ligand-Mediated … Y Yang, I Tikhonov, TJ Ruckwardt, M Djavani, JC Zapata, CD Pauza, ... Journal of Virology 77 (12), 6700-6708, 2003 | 133 | 2003 |
T cell immunity to SARS-CoV-2 following natural infection and vaccination AT DiPiazza, BS Graham, TJ Ruckwardt Biochemical and biophysical research communications 538, 211-217, 2021 | 126 | 2021 |
Quantitative and qualitative deficits in neonatal lung-migratory dendritic cells impact the generation of the CD8+ T cell response TJ Ruckwardt, AMW Malloy, KM Morabito, BS Graham PLoS pathogens 10 (2), e1003934, 2014 | 121 | 2014 |
Intranasal administration of RSV antigen-expressing MCMV elicits robust tissue-resident effector and effector memory CD8+ T cells in the lung KM Morabito, TR Ruckwardt, AJ Redwood, SM Moin, DA Price, ... Mucosal immunology 10 (2), 545-554, 2017 | 113 | 2017 |
COVID-19 vaccine mRNA-1273 elicits a protective immune profile in mice that is not associated with vaccine-enhanced disease upon SARS-CoV-2 challenge AT DiPiazza, SR Leist, OM Abiona, JI Moliva, A Werner, M Minai, ... Immunity 54 (8), 1869-1882. e6, 2021 | 93 | 2021 |
In vitro stimulation with a non‐peptidic alkylphosphate expands cells expressing Vγ2‐Jγ1.2/Vδ2 T‐cell receptors PS Evans, PJ Enders, C Yin, TJ Ruckwardt, M Malkovsky, CD Pauza Immunology 104 (1), 19-27, 2001 | 90 | 2001 |
Neonatal CD8 T-cell hierarchy is distinct from adults and is influenced by intrinsic T cell properties in respiratory syncytial virus infected mice TJ Ruckwardt, AMW Malloy, E Gostick, DA Price, P Dash, JL McClaren, ... PLoS pathogens 7 (12), e1002377, 2011 | 88 | 2011 |
Structure-based design with tag-based purification and in-process biotinylation enable streamlined development of SARS-CoV-2 spike molecular probes T Zhou, IT Teng, AS Olia, G Cerutti, J Gorman, A Nazzari, W Shi, ... Cell reports 33 (4), 2020 | 70 | 2020 |
Development of a potent Zika virus vaccine using self-amplifying messenger RNA K Luisi, KM Morabito, KE Burgomaster, M Sharma, WP Kong, ... Science advances 6 (32), eaba5068, 2020 | 70 | 2020 |
Responses against a subdominant CD8+ T cell epitope protect against immunopathology caused by a dominant epitope TJ Ruckwardt, C Luongo, AMW Malloy, J Liu, M Chen, PL Collins, ... The Journal of Immunology 185 (8), 4673-4680, 2010 | 67 | 2010 |
Thermoresponsive polymer nanoparticles co-deliver RSV F trimers with a TLR-7/8 adjuvant JR Francica, GM Lynn, R Laga, MG Joyce, TJ Ruckwardt, KM Morabito, ... Bioconjugate Chemistry 27 (10), 2372-2385, 2016 | 63 | 2016 |
Viruslike particles encapsidating respiratory syncytial virus M and M2 proteins induce robust T cell responses B Schwarz, KM Morabito, TJ Ruckwardt, DP Patterson, J Avera, ... ACS biomaterials science & engineering 2 (12), 2324-2332, 2016 | 62 | 2016 |