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Alexander Bagaev
Alexander Bagaev
BostonGene
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A probabilistic classification tool for genetic subtypes of diffuse large B cell lymphoma with therapeutic implications
GW Wright, JD Phelan, ZA Coulibaly, S Roulland, RM Young, JQ Wang, ...
Cancer cell 37 (4), 551-568. e14, 2020
9702020
Conserved pan-cancer microenvironment subtypes predict response to immunotherapy
A Bagaev, N Kotlov, K Nomie, V Svekolkin, A Gafurov, O Isaeva, N Osokin, ...
Cancer cell 39 (6), 845-865. e7, 2021
8052021
Clinical and biological subtypes of B-cell lymphoma revealed by microenvironmental signatures
N Kotlov, A Bagaev, MV Revuelta, JM Phillip, MT Cacciapuoti, ...
Cancer discovery 11 (6), 1468-1489, 2021
1812021
Elevated pre-activation basal level of nuclear NF-κB in native macrophages accelerates LPS-induced translocation of cytosolic NF-κB into the cell nucleus
AV Bagaev, AY Garaeva, ES Lebedeva, AV Pichugin, RI Ataullakhanov, ...
Scientific reports 9 (1), 4563, 2019
972019
Precise reconstruction of the TME using bulk RNA-seq and a machine learning algorithm trained on artificial transcriptomes
A Zaitsev, M Chelushkin, D Dyikanov, I Cheremushkin, B Shpak, K Nomie, ...
Cancer Cell 40 (8), 879-894. e16, 2022
822022
Follicular lymphoma microenvironment characteristics associated with tumor cell mutations and MHC class II expression
G Han, Q Deng, ML Marques-Piubelli, E Dai, M Dang, MCJ Ma, X Li, ...
Blood cancer discovery 3 (5), 428-443, 2022
702022
Lack of intrafollicular memory CD4+ T cells is predictive of early clinical failure in newly diagnosed follicular lymphoma
P Mondello, A Fama, MC Larson, AL Feldman, JC Villasboas, ZZ Yang, ...
Blood cancer journal 11 (7), 130, 2021
562021
Targeting TLR-4 with a novel pharmaceutical grade plant derived agonist, Immunomax®, as a therapeutic strategy for metastatic breast cancer
A Ghochikyan, A Pichugin, A Bagaev, A Davtyan, A Hovakimyan, ...
Journal of Translational Medicine 12, 1-12, 2014
562014
Neoantigen vaccination induces clinical and immunologic responses in non-small cell lung cancer patients harboring EGFR mutations
F Li, L Deng, KR Jackson, AH Talukder, AS Katailiha, SD Bradley, Q Zou, ...
Journal for immunotherapy of cancer 9 (7), 2021
492021
Primary 4T1 tumor resection provides critical “window of opportunity” for immunotherapy
A Ghochikyan, A Davtyan, A Hovakimyan, H Davtyan, A Poghosyan, ...
Clinical & experimental metastasis 31, 185-198, 2014
402014
Vaccination potential of B and T epitope-enriched NP and M2 against Influenza A viruses from different clades and hosts
I Tutykhina, I Esmagambetov, A Bagaev, A Pichugin, A Lysenko, ...
PLoS One 13 (1), e0191574, 2018
392018
Single-cell spatial proteomic revelations on the multiparametric MRI heterogeneity of clinically significant prostate cancer
RK Pachynski, EH Kim, N Miheecheva, N Kotlov, A Ramachandran, ...
Clinical Cancer Research 27 (12), 3478-3490, 2021
252021
Systems and methods for generating, visualizing and classifying molecular functional profiles
A Bagaev, F Frenkel, N Kotlov, R Ataullakhanov, O Isaeva
US Patent 11,367,509, 2022
232022
Systems and methods for generating, visualizing and classifying molecular functional profiles
A Bagaev, F Frenkel, N Kotlov, R Ataullakhanov, O Isaeva
US Patent 11,322,226, 2022
232022
Systems and methods for generating, visualizing and classifying molecular functional profiles
A Bagaev, F Frenkel, N Kotlov, R Ataullakhanov
US Patent 10,311,967, 2019
232019
Systems and methods for generating, visualizing and classifying molecular functional profiles
A Bagaev, F Frenkel, N Kotlov, R Ataullakhanov, O Isaeva
US Patent 11,430,545, 2022
192022
Systems and methods for generating, visualizing and classifying molecular functional profiles
A Bagaev, F Frenkel, N Kotlov, R Ataullakhanov
US Patent 10,650,911, 2020
192020
Systems and methods for identifying cancer treatments from normalized biomarker scores
A Bagaev, F Frenkel, R Ataullakhanov
US Patent App. 16/006,200, 2018
182018
The differences in immunoadjuvant mechanisms of TLR3 and TLR4 agonists on the level of antigen-presenting cells during immunization with recombinant adenovirus vector
E Lebedeva, A Bagaev, A Pichugin, M Chulkina, A Lysenko, I Tutykhina, ...
BMC immunology 19, 1-14, 2018
182018
Multi-omic profiling of follicular lymphoma reveals changes in tissue architecture and enhanced stromal remodeling in high-risk patients
AJ Radtke, E Postovalova, A Varlamova, A Bagaev, M Sorokina, ...
Cancer cell 42 (3), 444-463. e10, 2024
172024
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