Olmesartan ameliorates chemically-induced ulcerative colitis in rats via modulating NFκB and Nrf-2/HO-1 signaling crosstalk S Saber, RM Khalil, WS Abdo, D Nassif, E El-Ahwany Toxicology and applied pharmacology 364, 120-132, 2019 | 174 | 2019 |
Deferoxamine-loaded transfersomes accelerates healing of pressure ulcers in streptozotocin-induced diabetic rats SA El-Gizawy, A Nouh, S Saber, AY Kira Journal of Drug Delivery Science and Technology 58, 101732, 2020 | 76 | 2020 |
The dynamic interplay between AMPK/NFκB signaling and NLRP3 is a new therapeutic target in inflammation: Emerging role of dapagliflozin in overcoming lipopolysaccharide … EE Abd El-Fattah, S Saber, AAE Mourad, E El-Ahwany, NA Amin, ... Biomedicine & Pharmacotherapy 147, 112628, 2022 | 58 | 2022 |
Vildagliptin, a DPP-4 inhibitor, attenuates carbon tetrachloride-induced liver fibrosis by targeting ERK1/2, p38α, and NF-κB signaling R Khalil, A Shata, EM Abd El-Kader, H Sharaf, WS Abdo, NA Amin, ... Toxicology and applied pharmacology 407, 115246, 2020 | 58 | 2020 |
BBG enhances OLT1177-induced NLRP3 inflammasome inactivation by targeting P2X7R/NLRP3 and MyD88/NF-κB signaling in DSS-induced colitis in rats S Saber, ME Youssef, H Sharaf, NA Amin, R El-Shedody, FH Aboutouk, ... Life Sciences 270, 119123, 2021 | 56 | 2021 |
Novel complementary coloprotective effects of metformin and MCC950 by modulating HSP90/NLRP3 interaction and inducing autophagy in rats S Saber, EMA El-Kader Inflammopharmacology 29 (1), 237-251, 2021 | 55 | 2021 |
Mebendazole augments sensitivity to sorafenib by targeting MAPK and BCL-2 signalling in n-nitrosodiethylamine-induced murine hepatocellular carcinoma NS Younis, AMH Ghanim, S Saber Scientific reports 9 (1), 19095, 2019 | 54 | 2019 |
Perindopril, fosinopril and losartan inhibited the progression of diethylnitrosamine-induced hepatocellular carcinoma in mice via the inactivation of nuclear transcription … RHA Sameh Saber, Amr A.A. Mahmoud, Reham Goda, Noha S. Helal, Eman El-ahwany Toxicology Letters 295, 32-40, 2018 | 54 | 2018 |
A Novel Combination Therapy Using Rosuvastatin and Lactobacillus Combats Dextran Sodium Sulfate-Induced Colitis in High-Fat Diet-Fed Rats by Targeting the … S Saber, EE Abd El-Fattah, G Yahya, NA Gobba, AO Maghmomeh, ... Pharmaceuticals 14 (4), 341, 2021 | 53 | 2021 |
Combination of vitamin C and curcumin safeguards against methotrexate-induced acute liver injury in mice by synergistic antioxidant effects D Hasan Khudhair, AI Al-Gareeb, HM Al-Kuraishy, AH El-Kadem, ... Frontiers in medicine 9, 866343, 2022 | 52 | 2022 |
Novel complementary antitumour effects of celastrol and metformin by targeting IκBκB, apoptosis and NLRP3 inflammasome activation in diethylnitrosamine-induced murine … S Saber, AMH Ghanim, E El-Ahwany, EMA El-Kader Cancer chemotherapy and pharmacology 85 (2), 331-343, 2020 | 50 | 2020 |
In vitro and in vivo evaluation of cubosomal nanoparticles as an ocular delivery system for fluconazole in treatment of keratomycosis M Nasr, M Teiama, A Ismail, A Ebada, S Saber Drug Delivery and Translational Research 10, 1841-1852, 2020 | 46 | 2020 |
Novel potent and selective DPP-4 inhibitors: design, synthesis and molecular docking study of dihydropyrimidine phthalimide hybrids AAE Mourad, AE Khodir, S Saber, MAE Mourad Pharmaceuticals 14 (2), 144, 2021 | 45 | 2021 |
Empagliflozin adjunct with metformin for the inhibition of hepatocellular carcinoma progression: Emerging approach for new application AM Abdelhamid, S Saber, ME Youssef, AGA Gaafar, H Eissa, ... Biomedicine & Pharmacotherapy 145, 112455, 2022 | 44 | 2022 |
Dapagliflozin, an SGLT2 inhibitor, ameliorates acetic acid-induced colitis in rats by targeting NFκB/AMPK/NLRP3 axis MA El-Rous, S Saber, EM Raafat, AAE Ahmed Inflammopharmacology 29 (4), 1169-1185, 2021 | 44 | 2021 |
Telmisartan ameliorates dextran sodium sulfate-induced colitis in rats by modulating NF-κB signalling in the context of PPARγ agonistic activity S Saber, M Basuony, AS Eldin Archives of Biochemistry and Biophysics 671, 185-195, 2019 | 44 | 2019 |
Interference with the AMPKα/mTOR/NLRP3 signaling and the IL-23/IL-17 axis effectively protects against the dextran sulfate sodium intoxication in rats: A new paradigm in … ME Youssef, A El-Fattah, E Eslam, AM Abdelhamid, H Eissa, E El-Ahwany, ... Frontiers in Pharmacology, 2027, 2021 | 43 | 2021 |
Role of ganetespib, an HSP90 inhibitor, in cancer therapy: from molecular mechanisms to clinical practice ME Youssef, S Cavalu, AM Hasan, G Yahya, MA Abd-Eldayem, S Saber International Journal of Molecular Sciences 24 (5), 5014, 2023 | 42 | 2023 |
Unlocking the full potential of SGLT2 inhibitors: expanding applications beyond glycemic control ME Youssef, G Yahya, MS Popoviciu, S Cavalu, MA Abd-Eldayem, ... International Journal of Molecular Sciences 24 (7), 6039, 2023 | 40 | 2023 |
Albendazole-loaded cubosomes interrupt the ERK1/2-HIF-1α-p300/CREB axis in mice intoxicated with diethylnitrosamine: A new paradigm in drug repurposing for the inhibition of … S Saber, M Nasr, AS Saad, AAE Mourad, NA Gobba, A Shata, AM Hafez, ... Biomedicine & Pharmacotherapy 142, 112029, 2021 | 40 | 2021 |