Neutralization of tumor acidity improves antitumor responses to immunotherapy S Pilon-Thomas, KN Kodumudi, AE El-Kenawi, S Russell, AM Weber, ... Cancer research 76 (6), 1381-1390, 2016 | 606 | 2016 |
Spatial heterogeneity and evolutionary dynamics modulate time to recurrence in continuous and adaptive cancer therapies JA Gallaher, PM Enriquez-Navas, KA Luddy, RA Gatenby, ARA Anderson Cancer research 78 (8), 2127-2139, 2018 | 241 | 2018 |
Acidity promotes tumour progression by altering macrophage phenotype in prostate cancer A El-Kenawi, C Gatenbee, M Robertson-Tessi, R Bravo, J Dhillon, ... British journal of cancer 121 (7), 556-566, 2019 | 137 | 2019 |
T-cells produce acidic niches in lymph nodes to suppress their own effector functions H Wu, V Estrella, M Beatty, D Abrahams, A El-Kenawi, S Russell, ... Nature communications 11 (1), 4113, 2020 | 132 | 2020 |
Abscopal benefits of localized radiotherapy depend on activated T-cell trafficking and distribution between metastatic lesions JT Poleszczuk, KA Luddy, S Prokopiou, M Robertson-Tessi, EG Moros, ... Cancer research 76 (5), 1009-1018, 2016 | 125 | 2016 |
Hepatic tumor microenvironments and effects on NK cell phenotype and function J Piñeiro Fernández, KA Luddy, C Harmon, C O’Farrelly International journal of molecular sciences 20 (17), 4131, 2019 | 116 | 2019 |
Antagonism of adenosine A2A receptor expressed by lung adenocarcinoma tumor cells and cancer associated fibroblasts inhibits their growth M Mediavilla-Varela, K Luddy, D Noyes, FK Khalil, AM Neuger, H Soliman, ... Cancer biology & therapy 14 (9), 860-868, 2013 | 110 | 2013 |
Neoadjuvant radiotherapy of early-stage breast cancer and long-term disease-free survival J Poleszczuk, K Luddy, L Chen, JK Lee, LB Harrison, BJ Czerniecki, ... Breast cancer research 19, 1-7, 2017 | 93 | 2017 |
The effects of anesthetics and perioperative medications on immune function: a narrative review RS Ackerman, KA Luddy, BE Icard, JP Fernández, RA Gatenby, ... Anesthesia & Analgesia 133 (3), 676-689, 2021 | 72 | 2021 |
Tris–base buffer: a promising new inhibitor for cancer progression and metastasis A Ibrahim‐Hashim, D Abrahams, PM Enriquez‐Navas, K Luddy, ... Cancer medicine 6 (7), 1720-1729, 2017 | 61 | 2017 |
The role of toll-like receptors in colorectal cancer progression: evidence for epithelial to leucocytic transition KA Luddy, M Robertson-Tessi, NK Tafreshi, H Soliman, DL Morse Frontiers in immunology 5, 429, 2014 | 54 | 2014 |
Paclitaxel and TRAIL synergize to kill paclitaxel-resistant small cell lung cancer cells through a caspase-independent mechanism mediated through AIF TB Hunter, NJ Manimala, KA Luddy, T Catlin, SJ Antonia Anticancer research 31 (10), 3193-3204, 2011 | 45 | 2011 |
The goldilocks window of personalized chemotherapy: getting the immune response just right DS Park, M Robertson-Tessi, KA Luddy, PK Maini, MB Bonsall, ... Cancer research 79 (20), 5302-5315, 2019 | 42 | 2019 |
Predator-prey in tumor-immune interactions: A wrong model or just an incomplete one? I Kareva, KA Luddy, C O’Farrelly, RA Gatenby, JS Brown Frontiers in Immunology 12, 668221, 2021 | 33 | 2021 |
The immune checkpoint kick start: Optimization of neoadjuvant combination therapy using game theory J West, M Robertson-Tessi, K Luddy, DS Park, DFK Williamson, ... JCO clinical cancer informatics 3, 1-12, 2019 | 29 | 2019 |
Searching for Goldilocks: How evolution and ecology can help uncover more effective patient-specific chemotherapies DS Park, KA Luddy, M Robertson-Tessi, C O'Farrelly, RA Gatenby, ... Cancer research 80 (23), 5147-5154, 2020 | 14 | 2020 |
Feasibility of an evolutionary tumor board for generating novel personalized therapeutic strategies M Robertson-Tessi, JS Brown, MI Poole, M Johnson, A Marusyk, ... MedRxiv, 2023.01. 18.23284628, 2023 | 12 | 2023 |
Extracellular acidosis alters polarization of macrophages AE El-Kenawi, AA Ibrahim-Hashim, KA Luddy, SA Pilon-Thomas, ... Cancer Research 75 (15_Supplement), 3213-3213, 2015 | 12 | 2015 |
Transforming growth factor β signaling overcomes dasatinib resistance in lung cancer E Gordian, J Li, Y Pevzner, M Mediavilla-Varela, K Luddy, K Ohaegbulam, ... PLoS One 9 (12), e114131, 2014 | 10 | 2014 |
Tumor-immune metaphenotypes orchestrate an evolutionary bottleneck that promotes metabolic transformation J West, F Rentzeperis, C Adam, R Bravo, KA Luddy, M Robertson-Tessi, ... Frontiers in Immunology 15, 1323319, 2024 | 7 | 2024 |