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Alec S.T. Smith
Alec S.T. Smith
University of Washington, Department of Physiology and Biophysics
uw.edu의 이메일 확인됨 - 홈페이지
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Multi-Organ toxicity demonstration in a functional human in vitro system composed of four organs
C Oleaga, C Bernabini, AST Smith, B Srinivasan, M Jackson, W McLamb, ...
Scientific reports 6 (1), 20030, 2016
4392016
Microfabricated mammalian organ systems and their integration into models of whole animals and humans
JH Sung, MB Esch, JM Prot, CJ Long, A Smith, JJ Hickman, ML Shuler
Lab on a Chip 13 (7), 1201-1212, 2013
2862013
Nanotopography-induced structural anisotropy and sarcomere development in human cardiomyocytes derived from induced pluripotent stem cells
D Carson, M Hnilova, X Yang, CL Nemeth, JH Tsui, AST Smith, A Jiao, ...
ACS applied materials & interfaces 8 (34), 21923-21932, 2016
2202016
Biomimetic 3D tissue models for advanced high-throughput drug screening
KH Nam, AST Smith, S Lone, S Kwon, DH Kim
Journal of laboratory automation 20 (3), 201-215, 2015
1822015
How multi-organ microdevices can help foster drug development
MB Esch, AST Smith, JM Prot, C Oleaga, JJ Hickman, ML Shuler
Advanced drug delivery reviews 69, 158-169, 2014
1752014
Human iPSC-derived cardiomyocytes and tissue engineering strategies for disease modeling and drug screening
AST Smith, J Macadangdang, W Leung, MA Laflamme, DH Kim
Biotechnology advances 35 (1), 77-94, 2017
1532017
Micro-and nano-patterned conductive graphene–PEG hybrid scaffolds for cardiac tissue engineering
AST Smith, H Yoo, H Yi, EH Ahn, JH Lee, G Shao, E Nagornyak, ...
Chemical Communications 53 (53), 7412-7415, 2017
1112017
Characterization and optimization of a simple, repeatable system for the long term in vitro culture of aligned myotubes in 3D
AST Smith, S Passey, L Greensmith, V Mudera, MP Lewis
Journal of cellular biochemistry 113 (3), 1044-1053, 2012
1102012
TFPa/HADHA is required for fatty acid beta-oxidation and cardiolipin re-modeling in human cardiomyocytes
JW Miklas, E Clark, S Levy, D Detraux, A Leonard, K Beussman, ...
Nature Communications 10 (1), 4671, 2019
1012019
Tunable electroconductive decellularized extracellular matrix hydrogels for engineering human cardiac microphysiological systems
JH Tsui, A Leonard, ND Camp, JT Long, ZY Nawas, R Chavanachat, ...
Biomaterials 272, 120764, 2021
922021
In vitro differentiation of functional human skeletal myotubes in a defined system
X Guo, K Greene, N Akanda, AST Smith, M Stancescu, S Lambert, ...
Biomaterials science 2 (1), 131-138, 2014
912014
The effect of cell density on the maturation and contractile ability of muscle derived cells in a 3D tissue‐engineered skeletal muscle model and determination of the cellular …
V Mudera, AST Smith, MA Brady, MP Lewis
Journal of cellular physiology 225 (3), 646-653, 2010
772010
Nanopatterned human iPSC-based model of a dystrophin-null cardiomyopathic phenotype
J Macadangdang, X Guan, AST Smith, R Lucero, S Czerniecki, ...
Cellular and molecular bioengineering 8, 320-332, 2015
742015
Spatiotemporal control of cardiac anisotropy using dynamic nanotopographic cues
PY Mengsteab, K Uto, AST Smith, S Frankel, E Fisher, Z Nawas, ...
Biomaterials 86, 1-10, 2016
662016
Chromatin compartment dynamics in a haploinsufficient model of cardiac laminopathy
A Bertero, PA Fields, AST Smith, A Leonard, K Beussman, NJ Sniadecki, ...
Journal of Cell Biology 218 (9), 2919-2944, 2019
652019
Muscular dystrophy in a dish: engineered human skeletal muscle mimetics for disease modeling and drug discovery
AST Smith, J Davis, G Lee, DL Mack, DH Kim
Drug discovery today 21 (9), 1387-1398, 2016
632016
A functional system for high-content screening of neuromuscular junctions in vitro
AST Smith, CJ Long, K Pirozzi, JJ Hickman
Technology 1 (01), 37-48, 2013
602013
A more open approach is needed to develop cell-based fish technology: it starts with zebrafish
G Potter, AST Smith, NTK Vo, J Muster, W Weston, A Bertero, L Maves, ...
One Earth 3 (1), 54-64, 2020
552020
NanoMEA: a tool for high-throughput, electrophysiological phenotyping of patterned excitable cells
AST Smith, E Choi, K Gray, J Macadangdang, EH Ahn, EC Clark, ...
Nano Letters 20 (3), 1561-1570, 2019
502019
Advances and current challenges associated with the use of human induced pluripotent stem cells in modeling neurodegenerative disease
BJ Berry, AST Smith, JE Young, DL Mack
Cells Tissues Organs 205 (5-6), 331-349, 2019
502019
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