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Danielle Rux
Danielle Rux
UConn Health
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Inducible cassette exchange: a rapid and efficient system enabling conditional gene expression in embryonic stem and primary cells
M Iacovino, D Bosnakovski, H Fey, D Rux, G Bajwa, E Mahen, ...
Stem cells 29 (10), 1580-1588, 2011
2082011
SOX9 keeps growth plates and articular cartilage healthy by inhibiting chondrocyte dedifferentiation/osteoblastic redifferentiation
A Haseeb, R Kc, M Angelozzi, C de Charleroy, D Rux, RJ Tower, L Yao, ...
Proceedings of the National Academy of Sciences 118 (8), e2019152118, 2021
1692021
DNMT3A and TET1 cooperate to regulate promoter epigenetic landscapes in mouse embryonic stem cells
T Gu, X Lin, SM Cullen, M Luo, M Jeong, M Estecio, J Shen, S Hardikar, ...
Genome biology 19, 1-15, 2018
1672018
HoxA3 is an apical regulator of haemogenic endothelium
M Iacovino, D Chong, I Szatmari, L Hartweck, D Rux, A Caprioli, ...
Nature cell biology 13 (1), 72-78, 2011
1162011
Hox genes in the adult skeleton: Novel functions beyond embryonic development
DR Rux, DM Wellik
Developmental Dynamics 246 (4), 310-317, 2017
1122017
Regionally restricted Hox function in adult bone marrow multipotent mesenchymal stem/stromal cells
DR Rux, JY Song, IT Swinehart, KM Pineault, AJ Schlientz, KG Trulik, ...
Developmental cell 39 (6), 653-666, 2016
952016
Joints in the appendicular skeleton: developmental mechanisms and evolutionary influences
D Rux, RS Decker, E Koyama, M Pacifici
Current topics in developmental biology 133, 119-151, 2019
452019
Activin A promotes the development of acquired heterotopic ossification and is an effective target for disease attenuation in mice
C Mundy, L Yao, S Sinha, J Chung, D Rux, SE Catheline, E Koyama, ...
Science signaling 14 (669), eabd0536, 2021
302021
Hox11 Function Is Required for Region‐Specific Fracture Repair
DR Rux, JY Song, KM Pineault, GS Mandair, IT Swinehart, AJ Schlientz, ...
Journal of Bone and Mineral Research 32 (8), 1750-1760, 2017
302017
Impaired glucose metabolism underlies articular cartilage degeneration in osteoarthritis
K Li, X Ji, R Seeley, WC Lee, Y Shi, F Song, X Liao, C Song, X Huang, ...
The FASEB Journal 36 (6), e22377, 2022
292022
DNMT3A-coordinated splicing governs the stem state switch towards differentiation in embryonic and haematopoietic stem cells
R Ramabadran, JH Wang, JM Reyes, AG Guzman, S Gupta, C Rosas, ...
Nature cell biology 25 (4), 528-539, 2023
162023
Primary cilia direct murine articular cartilage tidemark patterning through hedgehog signaling and ambulatory load
D Rux, K Helbig, B Han, C Cortese, E Koyama, L Han, M Pacifici
Journal of Bone and Mineral Research 37 (6), 1097-1116, 2020
112020
Premature Growth Plate Closure Caused by a Hedgehog Cancer Drug Is Preventable by Co‐Administration of a Retinoid Antagonist in Mice
E Koyama, C Mundy, C Saunders, J Chung, SE Catheline, D Rux, ...
Journal of Bone and Mineral Research 36 (7), 1387-1402, 2020
102020
Hox11 expression characterizes developing zeugopod synovial joints and is coupled to postnatal articular cartilage morphogenesis into functional zones in mice
D Rux, K Helbig, E Koyama, M Pacifici
Developmental biology 477, 49-63, 2021
52021
Notch activation is required for downregulation of HoxA3-dependent endothelial cell phenotype during blood formation
V Sanghez, A Luzzi, D Clarke, D Kee, S Beuder, D Rux, M Osawa, ...
PloS one 12 (10), e0186818, 2017
42017
Activin A marks a novel progenitor cell population during fracture healing and reveals a therapeutic strategy
L Yao, J Lu, L Zhong, Y Wei, T Gui, L Wang, J Ahn, JD Boerckel, D Rux, ...
Elife 12, e89822, 2023
32023
Molecular diagnosis and novel genes and phenotypes in a pediatric thoracic insufficiency cohort
A Strong, M Behr, C Lott, AJ Clark, F Mentch, RP Da Silva, DR Rux, ...
Scientific Reports 13 (1), 991, 2023
12023
The methylomic landscape of human articular cartilage development contains epigenetic signatures of osteoarthritis risk
E McDonnell, SE Orr, MJ Barter, D Rux, A Brumwell, N Wrobel, L Murphy, ...
The American Journal of Human Genetics 111 (12), 2756-2772, 2024
2024
Epigenetic mechanisms of osteoarthritis risk in human skeletal development
E McDonnell, SE Orr, MJ Barter, D Rux, A Brumwell, N Wrobel, L Murphy, ...
medRxiv, 2024
2024
Superficial zone cell death in adult mouse limb joints leads to early onset osteoarthritic progression
D Rux, M Pacifici
Osteoarthritis and Cartilage 32, S34-S35, 2024
2024
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학술자료 1–20