Inducible cassette exchange: a rapid and efficient system enabling conditional gene expression in embryonic stem and primary cells M Iacovino, D Bosnakovski, H Fey, D Rux, G Bajwa, E Mahen, ... Stem cells 29 (10), 1580-1588, 2011 | 208 | 2011 |
SOX9 keeps growth plates and articular cartilage healthy by inhibiting chondrocyte dedifferentiation/osteoblastic redifferentiation A Haseeb, R Kc, M Angelozzi, C de Charleroy, D Rux, RJ Tower, L Yao, ... Proceedings of the National Academy of Sciences 118 (8), e2019152118, 2021 | 169 | 2021 |
DNMT3A and TET1 cooperate to regulate promoter epigenetic landscapes in mouse embryonic stem cells T Gu, X Lin, SM Cullen, M Luo, M Jeong, M Estecio, J Shen, S Hardikar, ... Genome biology 19, 1-15, 2018 | 167 | 2018 |
HoxA3 is an apical regulator of haemogenic endothelium M Iacovino, D Chong, I Szatmari, L Hartweck, D Rux, A Caprioli, ... Nature cell biology 13 (1), 72-78, 2011 | 116 | 2011 |
Hox genes in the adult skeleton: Novel functions beyond embryonic development DR Rux, DM Wellik Developmental Dynamics 246 (4), 310-317, 2017 | 112 | 2017 |
Regionally restricted Hox function in adult bone marrow multipotent mesenchymal stem/stromal cells DR Rux, JY Song, IT Swinehart, KM Pineault, AJ Schlientz, KG Trulik, ... Developmental cell 39 (6), 653-666, 2016 | 95 | 2016 |
Joints in the appendicular skeleton: developmental mechanisms and evolutionary influences D Rux, RS Decker, E Koyama, M Pacifici Current topics in developmental biology 133, 119-151, 2019 | 45 | 2019 |
Activin A promotes the development of acquired heterotopic ossification and is an effective target for disease attenuation in mice C Mundy, L Yao, S Sinha, J Chung, D Rux, SE Catheline, E Koyama, ... Science signaling 14 (669), eabd0536, 2021 | 30 | 2021 |
Hox11 Function Is Required for Region‐Specific Fracture Repair DR Rux, JY Song, KM Pineault, GS Mandair, IT Swinehart, AJ Schlientz, ... Journal of Bone and Mineral Research 32 (8), 1750-1760, 2017 | 30 | 2017 |
Impaired glucose metabolism underlies articular cartilage degeneration in osteoarthritis K Li, X Ji, R Seeley, WC Lee, Y Shi, F Song, X Liao, C Song, X Huang, ... The FASEB Journal 36 (6), e22377, 2022 | 29 | 2022 |
DNMT3A-coordinated splicing governs the stem state switch towards differentiation in embryonic and haematopoietic stem cells R Ramabadran, JH Wang, JM Reyes, AG Guzman, S Gupta, C Rosas, ... Nature cell biology 25 (4), 528-539, 2023 | 16 | 2023 |
Primary cilia direct murine articular cartilage tidemark patterning through hedgehog signaling and ambulatory load D Rux, K Helbig, B Han, C Cortese, E Koyama, L Han, M Pacifici Journal of Bone and Mineral Research 37 (6), 1097-1116, 2020 | 11 | 2020 |
Premature Growth Plate Closure Caused by a Hedgehog Cancer Drug Is Preventable by Co‐Administration of a Retinoid Antagonist in Mice E Koyama, C Mundy, C Saunders, J Chung, SE Catheline, D Rux, ... Journal of Bone and Mineral Research 36 (7), 1387-1402, 2020 | 10 | 2020 |
Hox11 expression characterizes developing zeugopod synovial joints and is coupled to postnatal articular cartilage morphogenesis into functional zones in mice D Rux, K Helbig, E Koyama, M Pacifici Developmental biology 477, 49-63, 2021 | 5 | 2021 |
Notch activation is required for downregulation of HoxA3-dependent endothelial cell phenotype during blood formation V Sanghez, A Luzzi, D Clarke, D Kee, S Beuder, D Rux, M Osawa, ... PloS one 12 (10), e0186818, 2017 | 4 | 2017 |
Activin A marks a novel progenitor cell population during fracture healing and reveals a therapeutic strategy L Yao, J Lu, L Zhong, Y Wei, T Gui, L Wang, J Ahn, JD Boerckel, D Rux, ... Elife 12, e89822, 2023 | 3 | 2023 |
Molecular diagnosis and novel genes and phenotypes in a pediatric thoracic insufficiency cohort A Strong, M Behr, C Lott, AJ Clark, F Mentch, RP Da Silva, DR Rux, ... Scientific Reports 13 (1), 991, 2023 | 1 | 2023 |
The methylomic landscape of human articular cartilage development contains epigenetic signatures of osteoarthritis risk E McDonnell, SE Orr, MJ Barter, D Rux, A Brumwell, N Wrobel, L Murphy, ... The American Journal of Human Genetics 111 (12), 2756-2772, 2024 | | 2024 |
Epigenetic mechanisms of osteoarthritis risk in human skeletal development E McDonnell, SE Orr, MJ Barter, D Rux, A Brumwell, N Wrobel, L Murphy, ... medRxiv, 2024 | | 2024 |
Superficial zone cell death in adult mouse limb joints leads to early onset osteoarthritic progression D Rux, M Pacifici Osteoarthritis and Cartilage 32, S34-S35, 2024 | | 2024 |