Optical pooled screens in human cells D Feldman, A Singh, JL Schmid-Burgk, RJ Carlson, A Mezger, AJ Garrity, ... Cell 179 (3), 787-799. e17, 2019 | 257 | 2019 |
IFIT1 exerts opposing regulatory effects on the inflammatory and interferon gene programs in LPS-activated human macrophages SP John, J Sun, RJ Carlson, B Cao, CJ Bradfield, J Song, M Smelkinson, ... Cell reports 25 (1), 95-106. e6, 2018 | 90 | 2018 |
Human STING is a proton channel B Liu, RJ Carlson, IS Pires, M Gentili, E Feng, Q Hellier, MA Schwartz, ... Science 381 (6657), 508-514, 2023 | 80 | 2023 |
ESCRT-dependent STING degradation inhibits steady-state and cGAMP-induced signalling M Gentili, B Liu, M Papanastasiou, D Dele-Oni, MA Schwartz, RJ Carlson, ... Nature Communications 14 (1), 611, 2023 | 58 | 2023 |
Pooled genetic perturbation screens with image-based phenotypes D Feldman, L Funk, A Le, RJ Carlson, MD Leiken, FN Tsai, B Soong, ... Nature protocols 17 (2), 476-512, 2022 | 48 | 2022 |
A genome-wide optical pooled screen reveals regulators of cellular antiviral responses RJ Carlson, MD Leiken, A Guna, N Hacohen, PC Blainey Proceedings of the National Academy of Sciences 120 (16), e2210623120, 2023 | 23 | 2023 |
Pooled optical screens in human cells D Feldman, A Singh, JL Schmid-Burgk, A Mezger, AJ Garrity, RJ Carlson, ... Biorxiv, 383943, 2018 | 17 | 2018 |
In situ cell screening methods and systems D Feldman, P Blainey, A Singh, R Carlson US Patent App. 17/055,502, 2022 | 5 | 2022 |
Terminal duplex stability and nucleotide identity differentially control siRNA loading and activity in RNA interference PA Angart, RJ Carlson, K Adu-Berchie, SP Walton nucleic acid therapeutics 26 (5), 309-317, 2016 | 5 | 2016 |
Use of Brevibacillus choshinensis for the production of biologically active brain-derived neurotrophic factor (BDNF) PA Angart, RJ Carlson, S Thorwall, S Patrick Walton Applied microbiology and biotechnology 101, 5645-5652, 2017 | 4 | 2017 |
IRAK1-mediated coincidence detection of microbial signals licenses inflammasome activation SJ Vayttaden, M Smelkinson, O Ernst, RJ Carlson, J Sun, C Bradfield, ... bioRxiv, 2019.12. 26.888776, 2019 | 3 | 2019 |
Classification and functional characterization of regulators of intracellular STING trafficking identified by genome-wide optical pooled screening M Gentili, RJ Carlson, B Liu, Q Hellier, J Andrews, Y Qin, PC Blainey, ... bioRxiv, 2024 | 2 | 2024 |
IFIT1 exerts opposing regulatory effects on the inflammatory and interferon gene programs in LPS-activated human macrophages SP John, J Sun, R Carlson, B Cao, ID Fraser The Journal of Immunology 198 (1_Supplement), 67.5-67.5, 2017 | 2 | 2017 |
Single-cell image-based genetic screens systematically identify regulators of Ebola virus subcellular infection dynamics RJ Carlson, JJ Patten, G Stefanakis, BY Soong, A Radhakrishnan, ... bioRxiv, 2024 | 1 | 2024 |
ESCRT-dependent STING degradation curtails steady-state and cGAMP-induced signaling M Gentili, B Liu, M Papanastasiou, D Dele-Oni, MA Schwartz, RJ Carlson, ... bioRxiv, 2022.09. 22.509044, 2022 | 1 | 2022 |
Relative quantification of siRNA strand loading into AGO2 for design of highly active siRNAs PA Angart, K Adu-Berchie, RJ Carlson, DB Vocelle, C Chan, SP Walton RNA Interference and Cancer Therapy: Methods and Protocols, 41-56, 2019 | 1 | 2019 |
IRAK1 attenuates TLR signaling and activates the inflammasome in response to dual-TLR stimulation SJ Vayttaden, M Smelkinson, OR Ernst, RJ Carlson, J Sun, RA Gottschalk, ... The Journal of Immunology 198 (1_Supplement), 75.11-75.11, 2017 | 1 | 2017 |