| Three-dimensional spheroids as in vitro preclinical models for cancer research B Pinto, AC Henriques, PMA Silva, H Bousbaa Pharmaceutics 12 (12), 1186, 2020 | 334 | 2020 |
| Mitosis inhibitors in anticancer therapy: When blocking the exit becomes a solution AC Henriques, D Ribeiro, J Pedrosa, B Sarmento, PMA Silva, H Bousbaa Cancer letters 440, 64-81, 2019 | 96 | 2019 |
| Monitoring the fidelity of mitotic chromosome segregation by the spindle assembly checkpoint P Silva, J Barbosa, AV Nascimento, J Faria, R Reis, H Bousbaa Cell proliferation 44 (5), 391-400, 2011 | 89 | 2011 |
| High CDC 20 expression is associated with poor prognosis in oral squamous cell carcinoma IMB Moura, ML Delgado, PMA Silva, CA Lopes, JB do Amaral, ... Journal of oral pathology & medicine 43 (3), 225-231, 2014 | 68 | 2014 |
| Second-generation antimitotics in cancer clinical trials P Novais, PMA Silva, I Amorim, H Bousbaa Pharmaceutics 13 (7), 1011, 2021 | 51 | 2021 |
| Dynein-dependent transport of spindle assembly checkpoint proteins off kinetochores toward spindle poles PMA Silva, RM Reis, VM Bolanos-Garcia, C Florindo, ÁA Tavares, ... FEBS letters 588 (17), 3265-3273, 2014 | 50 | 2014 |
| The spindle assembly checkpoint: perspectives in tumorigenesis and cancer therapy J Barbosa, AV Nascimento, J Faria, P Silva, H Bousbaa Frontiers in Biology 6, 147-155, 2011 | 45 | 2011 |
| Chalcone derivatives targeting mitosis: Synthesis, evaluation of antitumor activity and lipophilicity P Pinto, CM Machado, J Moreira, JDP Almeida, PMA Silva, AC Henriques, ... European Journal of Medicinal Chemistry 184, 111752, 2019 | 40 | 2019 |
| Targeting the spindle assembly checkpoint for breast cancer treatment S Marques, J Fonseca, P MA Silva, H Bousbaa Current cancer drug targets 15 (4), 272-281, 2015 | 37 | 2015 |
| Spindly and Bub3 expression in oral cancer: Prognostic and therapeutic implications PMA Silva, ML Delgado, N Ribeiro, C Florindo, AA Tavares, D Ribeiro, ... Oral Diseases 25 (5), 1291-1301, 2019 | 34 | 2019 |
| Suppression of spindly delays mitotic exit and exacerbates cell death response of cancer cells treated with low doses of paclitaxel PMA Silva, N Ribeiro, RT Lima, C Andrade, V Diogo, J Teixeira, ... Cancer Letters 394, 33-42, 2017 | 28 | 2017 |
| An overview of the spindle assembly checkpoint status in oral cancer JH Teixeira, PM Silva, RM Reis, IM Moura, S Marques, J Fonseca, ... BioMed research international 2014 (1), 145289, 2014 | 25 | 2014 |
| Generation of two paclitaxel-resistant high-grade serous carcinoma cell lines with increased expression of p-glycoprotein M Nunes, PMA Silva, R Coelho, C Pinto, A Resende, H Bousbaa, ... Frontiers in Oncology 11, 752127, 2021 | 24 | 2021 |
| Spindle assembly checkpoint as a potential target in colorectal cancer: current status and future perspectives V Diogo, J Teixeira, PMA Silva, H Bousbaa Clinical colorectal cancer 16 (1), 1-8, 2017 | 22 | 2017 |
| Combination therapy as a promising way to fight oral cancer JPN Silva, B Pinto, L Monteiro, PMA Silva, H Bousbaa Pharmaceutics 15 (6), 1653, 2023 | 20 | 2023 |
| Antagonizing the spindle assembly checkpoint silencing enhances paclitaxel and Navitoclax-mediated apoptosis with distinct mechanistic AC Henriques, PMA Silva, B Sarmento, H Bousbaa Scientific Reports 11 (1), 4139, 2021 | 19 | 2021 |
| New alkoxy flavone derivatives targeting caspases: Synthesis and antitumor activity evaluation J Moreira, D Ribeiro, PMA Silva, N Nazareth, M Monteiro, A Palmeira, ... Molecules 24 (1), 129, 2018 | 19 | 2018 |
| BUB3, beyond the Simple Role of Partner PMA Silva, H Bousbaa Pharmaceutics 14 (5), 1084, 2022 | 18 | 2022 |
| Prenylated chalcone 2 acts as an antimitotic agent and enhances the chemosensitivity of tumor cells to paclitaxel J Fonseca, S Marques, PMA Silva, P Brandão, H Cidade, MM Pinto, ... Molecules 21 (8), 982, 2016 | 18 | 2016 |
| Targeting Glucose Metabolism in Cancer Cells as an Approach to Overcoming Drug Resistance A Cunha, PMA Silva, B Sarmento, O Queirós Pharmaceutics 15 (11), 2610, 2023 | 17 | 2023 |