| Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours LA Donehower, M Harvey, BL Slagle, MJ McArthur, CA Montgomery Jr, ... Nature 356 (6366), 215-221, 1992 | 6228 | 1992 |
| Identification of mammalian microRNA host genes and transcription units A Rodriguez, S Griffiths-Jones, JL Ashurst, A Bradley Genome research 14 (10a), 1902-1910, 2004 | 2971 | 2004 |
| Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice P Soriano, C Montgomery, R Geske, A Bradley Cell 64 (4), 693-702, 1991 | 2544 | 1991 |
| p63 is a p53 homologue required for limb and epidermal morphogenesis AA Mills, B Zheng, XJ Wang, H Vogel, DR Roop, A Bradley Nature 398 (6729), 708-713, 1999 | 2498 | 1999 |
| Requirement of bic/microRNA-155 for normal immune function A Rodriguez, E Vigorito, S Clare, MV Warren, P Couttet, DR Soond, ... Science 316 (5824), 608-611, 2007 | 2412 | 2007 |
| Formation of germ-line chimaeras from embryo-derived teratocarcinoma cell lines A Bradley, M Evans, MH Kaufman, E Robertson Nature 309 (5965), 255-256, 1984 | 2246 | 1984 |
| Multiple defects of immune cell function in mice with disrupted interferon-γ genes DK Dalton, S Pitts-Meek, S Keshav, IS Figari, A Bradley, TA Stewart Science 259 (5102), 1739-1742, 1993 | 2232 | 1993 |
| Chk1 is an essential kinase that is regulated by Atr and required for the G2/M DNA damage checkpoint Q Liu, S Guntuku, XS Cui, S Matsuoka, D Cortez, K Tamai, G Luo, ... Genes & development 14 (12), 1448-1459, 2000 | 2211 | 2000 |
| Increased bone formation in osteocalcin-deficient mice P Ducy, C Desbois, B Boyce, G Pinero, B Story, C Dunstan, E Smith, ... Nature 382 (6590), 448-452, 1996 | 2195 | 1996 |
| Repair of double-strand breaks induced by CRISPR–Cas9 leads to large deletions and complex rearrangements M Kosicki, K Tomberg, A Bradley Nature biotechnology 36 (8), 765-771, 2018 | 1910 | 2018 |
| The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brain AP McMahon, A Bradley Cell 62 (6), 1073-1085, 1990 | 1909 | 1990 |
| A conditional knockout resource for the genome-wide study of mouse gene function WC Skarnes, B Rosen, AP West, M Koutsourakis, W Bushell, V Iyer, ... Nature 474 (7351), 337-342, 2011 | 1892 | 2011 |
| p53 mutant mice that display early ageing-associated phenotypes SD Tyner, S Venkatachalam, J Choi, S Jones, N Ghebranious, ... Nature 415 (6867), 45-53, 2002 | 1800 | 2002 |
| Muscle deficiency and neonatal death in mice with a targeted mutation in the myogenin gene P Hasty, A Bradley, JH Morris, DG Edmondson, JM Venuti, EN Olson, ... Nature 364 (6437), 501-506, 1993 | 1785 | 1993 |
| Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53 SN Jones, AE Roe, LA Donehower, A Bradley Nature 378 (6553), 206-208, 1995 | 1682 | 1995 |
| Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis EYHP Lee, CY Chang, N Hu, YCJ Wang, CC Lai, K Herrup, WH Lee, ... Nature 359 (6393), 288-294, 1992 | 1647 | 1992 |
| Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2 SK Sharan, M Morimatsu, U Albrecht, DS Lim, E Regel, C Dinh, A Sands, ... Nature 386 (6627), 804-810, 1997 | 1396 | 1997 |
| Impaired energy homeostasis in C/EBPα knockout mice N Wang, MJ Finegold, A Bradley, CN Ou, SV Abdelsayed, MD Wilde, ... Science 269 (5227), 1108-1112, 1995 | 1285 | 1995 |
| p53-independent expression of p21Cip1 in muscle and other terminally differentiating cells SB Parker, G Eichele, P Zhang, A Rawls, AT Sands, A Bradley, EN Olson, ... Science 267 (5200), 1024-1027, 1995 | 1283 | 1995 |
| Mice deficient for BMP2 are nonviable and have defects in amnion/chorion and cardiac development H Zhang, A Bradley Development 122 (10), 2977-2986, 1996 | 1266 | 1996 |
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