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William H. Parsons
William H. Parsons
Associate Professor, Oberlin College
oberlin.edu의 이메일 확인됨 - 홈페이지
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Saxitoxin
AP Thottumkara, WH Parsons, J Du Bois
Angewandte Chemie International Edition 53 (23), 5760-5784, 2014
1732014
Immunomodulatory lysophosphatidylserines are regulated by ABHD16A and ABHD12 interplay
SS Kamat, K Camara, WH Parsons, DH Chen, MM Dix, TD Bird, ...
Nature Chemical Biology 11 (2), 164-171, 2015
1712015
A calcium-dependent acyltransferase that produces N-acyl phosphatidylethanolamines
Y Ogura, WH Parsons, SS Kamat, BF Cravatt
Nature Chemical Biology, 2016
1302016
Marked difference in saxitoxin and tetrodotoxin affinity for the human nociceptive voltage-gated sodium channel (Nav1. 7)
JR Walker, PA Novick, WH Parsons, M McGregor, J Zablocki, VS Pande, ...
Proceedings of the National Academy of Sciences 109 (44), 18102-18107, 2012
1092012
AIG1 and ADTRP are atypical integral membrane hydrolases that degrade bioactive FAHFAs
WH Parsons, MJ Kolar, SS Kamat, AB Cognetta III, JJ Hulce, E Saez, ...
Nature Chemical Biology 12, 367-372, 2016
872016
Branched Fatty Acid Esters of Hydroxy Fatty Acids Are Preferred Substrates of the MODY8 Protein Carboxyl Ester Lipase
MJ Kolar, SS Kamat, WH Parsons, EA Homan, T Maher, OD Peroni, ...
Biochemistry 55 (33), 4636-4641, 2016
712016
Fluorescent saxitoxins for live cell imaging of single voltage-gated sodium ion channels beyond the optical diffraction limit
AE Ondrus, DL Hsiao-lu, S Iwanaga, WH Parsons, BM Andresen, ...
Chemistry & biology 19 (7), 902-912, 2012
652012
Pharmacological convergence reveals a lipid pathway that regulates C. elegans lifespan
AL Chen, KM Lum, P Lara-Gonzalez, D Ogasawara, AB Cognetta III, A To, ...
Nature chemical biology 15 (5), 453-462, 2019
492019
AIG1 and ADTRP are endogenous hydrolases of fatty acid esters of hydroxy fatty acids (FAHFAs) in mice
ME Ertunc, BP Kok, WH Parsons, JG Wang, D Tan, CJ Donaldson, ...
Journal of Biological Chemistry 295 (18), 5891-5905, 2020
412020
A 18F-labeled saxitoxin derivative for in vivo PET-MR imaging of voltage-gated sodium channel expression following nerve injury
A Hoehne, D Behera, WH Parsons, ML James, B Shen, P Borgohain, ...
Journal of the American Chemical Society 135 (48), 18012-18015, 2013
382013
Maleimide conjugates of saxitoxin as covalent inhibitors of voltage-gated sodium channels
WH Parsons, J Du Bois
Journal of the American Chemical Society 135 (29), 10582-10585, 2013
352013
Activity-Based Hydrazine Probes for Protein Profiling of Electrophilic Functionality in Therapeutic Targets
Z Lin, X Wang, KA Bustin, K Shishikura, NR McKnight, L He, RM Suciu, ...
ACS central science 7 (9), 1524-1534, 2021
342021
Solid-state 17O NMR study of benzoic acid adsorption on metal oxide surfaces
EW Hagaman, B Chen, J Jiao, W Parsons
Solid State Nuclear Magnetic Resonance 41, 60-67, 2012
282012
Discovery of Potent and Selective Inhibitors against Protein-Derived Electrophilic Cofactors
X Wang, Z Lin, KA Bustin, NR McKnight, WH Parsons, ML Matthews
Journal of the American Chemical Society 144 (12), 5377-5388, 2022
252022
Development of succinimide-based inhibitors for the mitochondrial rhomboid protease PARL
WH Parsons, NT Rutland, JA Crainic, JM Cardozo, AS Chow, CL Andrews, ...
Bioorganic & Medicinal Chemistry Letters 49, 128290, 2021
82021
Saxitoxin-derived Probes for the Study of Voltage-gated Sodium Channels in Living Cells and Animals
WH Parsons
Stanford University, 2013
12013
Activity-Based Protein Profiling of RHBDL4 Reveals Proteolysis of the Enzyme and a Distinct Inhibitor Profile
CC Davies, RM Hu, PJ Kamitsuka, GN Morais, RS de Gonzalez, ...
ACS Chemical Biology 19 (8), 1674-1682, 2024
2024
Hydrazines as versatile chemical biology probes and drug-discovery tools for cofactor-dependent enzymes
Z Lin, X Wang, KA Bustin, L He, RM Suciu, N Schek, M Ahmadi, K Hu, ...
bioRxiv, 2020.06. 17.154864, 2020
2020
Hydrazines as versatile chemical biology probes and drug-discovery tools for cofactor-dependent enzymes [preprint]
Z Lin, X Wang, KA Bustin, L He, RM Suciu, N Schek, M Ahmadi, K Hu, ...
2020
Lactone compounds and methods of making and using same
BF Cravatt, SS Kamat, WH Parsons, AR Howell, K Camara, A Anderson
US Patent App. 15/520,389, 2017
2017
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학술자료 1–20