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Desiree Böck
Desiree Böck
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In situ architecture, function, and evolution of a contractile injection system
D Böck, JM Medeiros, HF Tsao, T Penz, GL Weiss, K Aistleitner, M Horn, ...
Science 357 (6352), 713-717, 2017
1572017
In vivo prime editing of a metabolic liver disease in mice
D Böck, T Rothgangl, L Villiger, L Schmidheini, M Matsushita, N Mathis, ...
Science translational medicine 14 (636), eabl9238, 2022
1352022
Intestinal epithelial NAIP/NLRC4 restricts systemic dissemination of the adapted pathogen Salmonella Typhimurium due to site-specific bacterial PAMP expression
A Hausmann, D Böck, P Geiser, DL Berthold, SA Fattinger, M Furter, ...
Mucosal immunology 13 (3), 530-544, 2020
1152020
The in situ structures of mono-, di-, and trinucleosomes in human heterochromatin
S Cai, D Böck, M Pilhofer, L Gan
Molecular biology of the cell 29 (20), 2450-2457, 2018
912018
Robust workflow and instrumentation for cryo-focused ion beam milling of samples for electron cryotomography
JM Medeiros, D Böck, GL Weiss, R Kooger, RA Wepf, M Pilhofer
Ultramicroscopy 190, 1-11, 2018
672018
Prevalence and comparison of Streptococcus infantarius subsp. infantarius and Streptococcus gallolyticus subsp. macedonicus in raw and fermented dairy products from East and …
C Jans, DWM Kaindi, D Böck, PMK Njage, SM Kouamé-Sina, B Bonfoh, ...
International journal of food microbiology 167 (2), 186-195, 2013
522013
Salmonella Typhimurium discreet-invasion of the murine gut absorptive epithelium
SA Fattinger, D Böck, ML Di Martino, S Deuring, P Samperio Ventayol, ...
PLoS pathogens 16 (5), e1008503, 2020
512020
Phylogenetic, epidemiological and functional analyses of the Streptococcus bovis/Streptococcus equinus complex through an overarching MLST scheme
C Jans, T de Wouters, B Bonfoh, C Lacroix, DWM Kaindi, J Anderegg, ...
BMC microbiology 16, 1-16, 2016
482016
Imaging bacteria inside their host by cryo-focused ion beam milling and electron cryotomography
JM Medeiros, D Böck, M Pilhofer
Current opinion in microbiology 43, 62-68, 2018
322018
Continuous directed evolution of a compact CjCas9 variant with broad PAM compatibility
L Schmidheini, N Mathis, KF Marquart, T Rothgangl, L Kissling, D Böck, ...
Nature Chemical Biology 20 (3), 333-343, 2024
202024
The Polar Legionella Icm/Dot T4SS Establishes Distinct Contact Sites with the Pathogen Vacuole Membrane
D Böck, D Hüsler, B Steiner, JM Medeiros, A Welin, KA Radomska, ...
MBio 12 (5), 10.1128/mbio. 02180-21, 2021
172021
CryoEM of bacterial secretion systems
R Kooger, P Szwedziak, D Böck, M Pilhofer
Current opinion in structural biology 52, 64-70, 2018
132018
Machine learning prediction of prime editing efficiency across diverse chromatin contexts
N Mathis, A Allam, A Tálas, L Kissling, E Benvenuto, L Schmidheini, ...
Nature Biotechnology, 1-8, 2024
122024
The large GTPase Sey1/atlastin mediates lipid droplet-and FadL-dependent intracellular fatty acid metabolism of Legionella pneumophila
D Hüsler, P Stauffer, B Keller, D Böck, T Steiner, A Ostrzinski, S Vormittag, ...
Elife 12, e85142, 2023
122023
Intestinal epithelial NAIP/NLRC4 restricts systemic dissemination of the adapted pathogen Salmonella Typhimurium due to site-specific bacterial PAMP expression. Mucosal Immunol …
A Hausmann, D Böck, P Geiser, DL Berthold, SA Fattinger, M Furter, ...
S41385-019-0247-0, 2020
92020
Enhancing prime editor activity by directed protein evolution in yeast
Y Weber, D Böck, A Ivașcu, N Mathis, T Rothgangl, EI Ioannidi, AC Blaudt, ...
Nature Communications 15 (1), 2092, 2024
72024
Treatment of a metabolic liver disease by in vivo prime editing in mice
D Böck, T Rothgangl, L Villiger, L Schmidheini, N Mathis, E Ioannidi, ...
biorxiv, 2021.08. 17.456632, 2021
62021
Predicting prime editing efficiency across diverse edit types and chromatin contexts with machine learning
N Mathis, A Allam, A Tálas, E Benvenuto, R Schep, T Damodharan, ...
bioRxiv, 2023.10. 09.561414, 2023
32023
Prime editing of the β1 adrenoceptor in the brain reprograms mouse behavior
D Böck, L Tidecks, M Wilhelm, Y Weber, E Ioannidi, J Mumenthaler, ...
BioRxiv, 2023.05. 19.541410, 2023
22023
In vivo base editing of a pathogenic Eif2b5 variant improves vanishing white matter phenotypes in mice
D Böck, IM Revers, ASJ Bomhof, AEJ Hillen, C Boeijink, L Kissling, S Egli, ...
Molecular therapy 32 (5), 1328-1343, 2024
12024
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