| The mitochondrial apoptotic effectors BAX/BAK activate caspase-3 and-7 to trigger NLRP3 inflammasome and caspase-8 driven IL-1β activation JE Vince, D De Nardo, W Gao, AJ Vince, C Hall, K McArthur, D Simpson, ... Cell reports 25 (9), 2339-2353. e4, 2018 | 213 | 2018 |
| The pyroptotic cell death effector gasdermin D is activated by gout-associated uric acid crystals but is dispensable for cell death and IL-1β release M Rashidi, DS Simpson, A Hempel, D Frank, E Petrie, A Vince, R Feltham, ... The Journal of Immunology 203 (3), 736-748, 2019 | 122 | 2019 |
| Specific NLRP3 inhibition protects against diabetes-associated atherosclerosis A Sharma, JSY Choi, N Stefanovic, A Al-Sharea, DS Simpson, ... Diabetes 70 (3), 772-787, 2021 | 119 | 2021 |
| Stressing out the mitochondria: Mechanistic insights into NLRP3 inflammasome activation M Yabal, DJ Calleja, DS Simpson, KE Lawlor Journal of leukocyte biology 105 (2), 377-399, 2019 | 105 | 2019 |
| Interferon-γ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway DS Simpson, J Pang, A Weir, IY Kong, M Fritsch, M Rashidi, JP Cooney, ... Immunity 55 (3), 423-441. e9, 2022 | 97 | 2022 |
| The ubiquitylation of IL-1β limits its cleavage by caspase-1 and targets it for proteasomal degradation SL Vijayaraj, R Feltham, M Rashidi, D Frank, Z Liu, DS Simpson, G Ebert, ... Nature Communications 12 (1), 2713, 2021 | 67 | 2021 |
| RIPK1 prevents TRADD-driven, but TNFR1 independent, apoptosis during development H Anderton, E Bandala-Sanchez, DS Simpson, JA Rickard, AP Ng, ... Cell Death & Differentiation 26 (5), 877-889, 2019 | 64 | 2019 |
| Loss-of-function but not gain-of-function properties of mutant TP53 are critical for the proliferation, survival, and metastasis of a broad range of cancer cells Z Wang, M Burigotto, S Ghetti, F Vaillant, T Tan, BD Capaldo, M Palmieri, ... Cancer Discovery 14 (2), 362-379, 2024 | 37 | 2024 |
| Caspase‐8‐driven apoptotic and pyroptotic crosstalk causes cell death and IL‐1β release in X‐linked inhibitor of apoptosis (XIAP) deficiency SA Hughes, M Lin, A Weir, B Huang, L Xiong, NK Chua, J Pang, ... The EMBO Journal 42 (5), e110468, 2023 | 34 | 2023 |
| Candida auris uses metabolic strategies to escape and kill macrophages while avoiding robust activation of the NLRP3 inflammasome response H Weerasinghe, C Simm, TM Djajawi, I Tedja, TL Lo, DS Simpson, ... Cell Reports 42 (5), 2023 | 22 | 2023 |
| Development of NanoLuc-targeting protein degraders and a universal reporter system to benchmark tag-targeted degradation platforms C Grohmann, CM Magtoto, JR Walker, NK Chua, A Gabrielyan, M Hall, ... Nature Communications 13 (1), 2073, 2022 | 22 | 2022 |
| RIPK1 ubiquitination: Evidence, correlations and the undefined DS Simpson, A Gabrielyan, R Feltham Seminars in Cell & Developmental Biology 109, 76-85, 2021 | 19 | 2021 |
| The mitochondrial apoptotic effectors BAX/BAK activate caspase-3 and-7 to trigger NLRP3 inflammasome and caspase-8-driven IL-1beta activation. Cell Rep 25 (9): 2339–2353. e2334 JE Vince, D De Nardo, W Gao, AJ Vince, C Hall, K McArthur, D Simpson, ... | 8 | 2018 |
| A1 is induced by pathogen ligands to limit myeloid cell death and NLRP3 inflammasome activation M Speir, H Tye, TA Gottschalk, DS Simpson, TM Djajawi, P Deo, ... EMBO reports, e56865, 2023 | 3 | 2023 |
| Impact of ethnicity and social deprivation on uptake of structured education for type 1 diabetes in a multi-ethnic urban population D Hopkins, R Foxcroft, D Simpson, T Evans, S Thomas, A Simonds, ... 49th Annual Meeting of the European-Association-for-the-Study-of-Diabetes …, 2013 | 2 | 2013 |
| Divergent roles of RIPK3 and MLKL in high-fat diet–induced obesity and MAFLD in mice H Tye, SA Conos, TM Djajawi, TA Gottschalk, N Abdoulkader, IY Kong, ... Life Science Alliance 8 (1), 2025 | 1 | 2025 |
| Divergent roles for caspase-8 and MLKL in high-fat diet induced obesity and NAFLD in mice H Tye, SA Conos, TM Djajawi, N Abdoulkader, IY Kong, HL Kammoun, ... bioRxiv, 2023.03. 14.532682, 2023 | 1 | 2023 |
| Correction to: RIPK1 prevents TRADD-driven, but TNFR1 independent, apoptosis during development H Anderton, E Bandala-Sanchez, DS Simpson, JA Rickard, AP Ng, ... Cell Death and Differentiation 31 (12), 1776, 2024 | | 2024 |
| Mind bomb 2 limits inflammatory dermatitis in Sharpin mutant mice independently of cell death DS Simpson, H Anderton, J Yousef, V Vaibhav, SA Cobbold, ... PNAS nexus 3 (1), pgad438, 2024 | | 2024 |
| The Australasian Cell Death Society (ACDS): celebrating 50 years of Australasian cell death research. M Speir, AH Chan, DS Simpson, T Khan, TL Saunders, IKH Poon, ... Immunology & Cell Biology 100 (1), 2022 | | 2022 |
James E VinceThe Walter and Eliza Hall Institute of Medical Researchwehi.edu.au의 이메일 확인됨
