| A high-fidelity Cas9 mutant delivered as a ribonucleoprotein complex enables efficient gene editing in human hematopoietic stem and progenitor cells CA Vakulskas, DP Dever, GR Rettig, R Turk, AM Jacobi, MA Collingwood, ... Nature medicine 24 (8), 1216-1224, 2018 | 812 | 2018 |
| Highly efficient editing of the β-globin gene in patient-derived hematopoietic stem and progenitor cells to treat sickle cell disease SH Park, CM Lee, DP Dever, TH Davis, J Camarena, W Srifa, Y Zhang, ... Nucleic acids research 47 (15), 7955-7972, 2019 | 155 | 2019 |
| Activation of transmembrane bile acid receptor TGR5 modulates pancreatic islet α cells to promote glucose homeostasis DP Kumar, A Asgharpour, F Mirshahi, SH Park, S Liu, Y Imai, JL Nadler, ... Journal of Biological Chemistry 291 (13), 6626-6640, 2016 | 143 | 2016 |
| CRISPR/Cas9 Gene Editing for Curing Sickle Cell Disease SH Park, G Bao Transfusion and Apheresis Science, 103060, 2021 | 92 | 2021 |
| In Vivo Ryr2 Editing Corrects Catecholaminergic Polymorphic Ventricular Tachycardia X Pan, L Philippen, SK Lahiri, C Lee, SH Park, TA Word, N Li, KE Jarrett, ... Circulation research 123 (8), 953-963, 2018 | 87 | 2018 |
| Comprehensive analysis and accurate quantification of unintended large gene modifications induced by CRISPR-Cas9 gene editing SH Park, M Cao, Y Pan, TH Davis, L Saxena, H Deshmukh, Y Fu, ... Science Advances 8 (42), eabo7676, 2022 | 48 | 2022 |
| Multiplexed high-throughput localized electroporation workflow with deep learning–based analysis for cell engineering CA Patino, N Pathak, P Mukherjee, SH Park, G Bao, HD Espinosa Science Advances 8 (29), eabn7637, 2022 | 36 | 2022 |
| Therapeutic CRISPR/Cas9 genome editing for treating sickle cell disease SH Park, CM Lee, H Deshmukh, G Bao Blood 128 (22), 4703, 2016 | 29 | 2016 |
| 12-Lipoxygenase inhibitor improves functions of cytokine-treated human islets and type 2 diabetic islets K Ma, A Xiao, SH Park, L Glenn, L Jackson, T Barot, JR Weaver, ... The Journal of Clinical Endocrinology & Metabolism 102 (8), 2789-2797, 2017 | 26 | 2017 |
| A novel neighbor housing environment enhances social interaction and rescues cognitive deficits from social isolation in adolescence AB Pais, AC Pais, G Elmisurati, SH Park, MF Miles, JT Wolstenholme Brain Sciences 9 (12), 336, 2019 | 23 | 2019 |
| LPA disruption with AAV-CRISPR potently lowers plasma apo (a) in transgenic mouse model: A proof-of-concept study. AM Doerfler, SH Park, JM Assini, A Youssef, L Saxena, AB Yaseen, ... Molecular Therapy-Methods & Clinical Development, 2022 | 20 | 2022 |
| Integrating micro and nano technologies for cell engineering and analysis: toward the next generation of cell therapy workflows P Mukherjee, SH Park, N Pathak, CA Patino, G Bao, HD Espinosa ACS nano 16 (10), 15653-15680, 2022 | 10 | 2022 |
| Detection and quantification of unintended large on-target gene modifications due to CRISPR/Cas9 editing SH Park, M Cao, G Bao Current Opinion in Biomedical Engineering 28, 100478, 2023 | 7 | 2023 |
| High levels of lipoprotein (a) in transgenic mice exacerbate atherosclerosis and promote vulnerable plaque features in a sex-specific manner JM Assini, JR Clark, A Youssef, C Xing, AM Doerfler, SH Park, L Saxena, ... Atherosclerosis 384, 117150, 2023 | 7 | 2023 |
| Engineered human umbilical cord derived erythroid progenitor cells (HUDEP2) with sickle or β-thalassemia mutation: An in-vitro system for testing pharmacological induction of … SH Park, CM Lee, Y Zhang, A Chang, VA Sheehan, G Bao Blood 132, 3478, 2018 | 4 | 2018 |
| Gene editing-based targeted integration for correction of Wiskott-Aldrich syndrome M Pille, JM Avila, SH Park, CQ Le, H Xue, F Haerynck, L Saxena, C Lee, ... Molecular Therapy Methods & Clinical Development 32 (1), 2024 | 3 | 2024 |
| In vivo expansion of gene-targeted hepatocytes through transient inhibition of an essential gene M De Giorgi, SH Park, A Castoreno, M Cao, A Hurley, L Saxena, ... bioRxiv, 2023 | 3 | 2023 |
| Host factors alter effects of angiopoietin-like protein 8 on glucose homeostasis in diabetic mice S Liu, EM Smith, TH King, L Glenn, M Trevino, SH Park, Y Machida, ... Journal of diabetes mellitus 6 (4), 277, 2016 | 2 | 2016 |
| Long-term efficacy and safety of cardiac genome editing for catecholaminergic polymorphic ventricular tachycardia OM Moore, Y Aguilar-Sanchez, SK Lahiri, MM Hulsurkar, ... The Journal of Cardiovascular Aging 4 (1), N/A-N/A, 2024 | 1 | 2024 |
| Characterization of hemoglobin variants due to in-frame deletions in the β-globin gene from CRISPR/Cas9 gene correction for sickle cell disease AA Pendergast, SH Park, LA Binns, CK Kanne, C Karsenty, ... Blood 140 (Supplement 1), 7793-7794, 2022 | 1 | 2022 |
Gang BaoFoyt Family Professor, Bioengineering, Rice Universityrice.edu의 이메일 확인됨