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Rafael De Cabo
Rafael De Cabo
다른 이름Rafael DeCabo, Rafael d Cabo, Rafa de Cabo
Translational Gerontology Branch, National Institute on Aging
grc.nia.nih.gov의 이메일 확인됨
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Resveratrol improves health and survival of mice on a high-calorie diet
JA Baur, KJ Pearson, NL Price, HA Jamieson, C Lerin, A Kalra, ...
Nature 444 (7117), 337-342, 2006
54632006
Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase
HY Cohen, C Miller, KJ Bitterman, NR Wall, B Hekking, B Kessler, ...
science 305 (5682), 390-392, 2004
24452004
Suppression of oxidative stress by β-hydroxybutyrate, an endogenous histone deacetylase inhibitor
T Shimazu, MD Hirschey, J Newman, W He, K Shirakawa, N Le Moan, ...
Science 339 (6116), 211-214, 2013
17642013
SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function
NL Price, AP Gomes, AJY Ling, FV Duarte, A Martin-Montalvo, BJ North, ...
Cell metabolism 15 (5), 675-690, 2012
17242012
Effects of intermittent fasting on health, aging, and disease
R De Cabo, MP Mattson
New England Journal of Medicine 381 (26), 2541-2551, 2019
15712019
Metformin improves healthspan and lifespan in mice
A Martin-Montalvo, EM Mercken, SJ Mitchell, HH Palacios, PL Mote, ...
Nature communications 4 (1), 2192, 2013
15552013
Declining NAD+ induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging
AP Gomes, NL Price, AJY Ling, JJ Moslehi, MK Montgomery, L Rajman, ...
Cell 155 (7), 1624-1638, 2013
15492013
Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span
KJ Pearson, JA Baur, KN Lewis, L Peshkin, NL Price, N Labinskyy, ...
Cell metabolism 8 (2), 157-168, 2008
14022008
Impact of caloric restriction on health and survival in rhesus monkeys from the NIA study
JA Mattison, GS Roth, TM Beasley, EM Tilmont, AM Handy, RL Herbert, ...
Nature 489 (7415), 318-321, 2012
13612012
Nutrient-sensitive mitochondrial NAD+ levels dictate cell survival
H Yang, T Yang, JA Baur, E Perez, T Matsui, JJ Carmona, DW Lamming, ...
Cell 130 (6), 1095-1107, 2007
11382007
Rapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous mice
RA Miller, DE Harrison, CM Astle, JA Baur, AR Boyd, R De Cabo, ...
Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences …, 2011
10052011
Intermittent fasting dissociates beneficial effects of dietary restriction on glucose metabolism and neuronal resistance to injury from calorie intake
RM Anson, Z Guo, R de Cabo, T Iyun, M Rios, A Hagepanos, DK Ingram, ...
Proceedings of the National Academy of Sciences 100 (10), 6216-6220, 2003
9572003
Caloric restriction improves health and survival of rhesus monkeys
JA Mattison, RJ Colman, TM Beasley, DB Allison, JW Kemnitz, GS Roth, ...
Nature communications 8 (1), 14063, 2017
8902017
Growth hormone receptor deficiency is associated with a major reduction in pro-aging signaling, cancer, and diabetes in humans
J Guevara-Aguirre, P Balasubramanian, M Guevara-Aguirre, M Wei, ...
Science translational medicine 3 (70), 70ra13-70ra13, 2011
8722011
Fasting cycles retard growth of tumors and sensitize a range of cancer cell types to chemotherapy
C Lee, L Raffaghello, S Brandhorst, FM Safdie, G Bianchi, ...
Science translational medicine 4 (124), 124ra27-124ra27, 2012
8662012
Calorie restriction induces mitochondrial biogenesis and bioenergetic efficiency
G López-Lluch, N Hunt, B Jones, M Zhu, H Jamieson, S Hilmer, ...
Proceedings of the National Academy of Sciences 103 (6), 1768-1773, 2006
8012006
The SIRT1 deacetylase suppresses intestinal tumorigenesis and colon cancer growth
R Firestein, G Blander, S Michan, P Oberdoerffer, S Ogino, J Campbell, ...
PloS one 3 (4), e2020, 2008
7492008
The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance
C Lee, J Zeng, BG Drew, T Sallam, A Martin-Montalvo, J Wan, SJ Kim, ...
Cell metabolism 21 (3), 443-454, 2015
6672015
Mechanisms of vascular aging: new perspectives
Z Ungvari, G Kaley, R De Cabo, WE Sonntag, A Csiszar
Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences …, 2010
6632010
Interventions to slow aging in humans: are we ready?
VD Longo, A Antebi, A Bartke, N Barzilai, HM Brown‐Borg, C Caruso, ...
Aging cell 14 (4), 497-510, 2015
6542015
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