Longitudinal molecular trajectories of diffuse glioma in adults FP Barthel, KC Johnson, FS Varn, AD Moskalik, G Tanner, E Kocakavuk, ... Nature 576 (7785), 112-120, 2019 | 481 | 2019 |
Glioma progression is shaped by genetic evolution and microenvironment interactions FS Varn, KC Johnson, J Martinek, JT Huse, MLP Nasrallah, P Wesseling, ... Cell 185 (12), 2184-2199. e16, 2022 | 288 | 2022 |
Immunoregulatory functions of VISTA EC Nowak, JL Lines, FS Varn, J Deng, A Sarde, R Mabaera, A Kuta, ... Immunological reviews 276 (1), 66-79, 2017 | 221 | 2017 |
Hypoxia-induced VISTA promotes the suppressive function of myeloid-derived suppressor cells in the tumor microenvironment J Deng, J Li, A Sarde, JL Lines, YC Lee, DC Qian, DA Pechenick, ... Cancer immunology research 7 (7), 1079-1090, 2019 | 190 | 2019 |
Single-cell multimodal glioma analyses identify epigenetic regulators of cellular plasticity and environmental stress response KC Johnson, KJ Anderson, ET Courtois, AD Gujar, FP Barthel, FS Varn, ... Nature genetics 53 (10), 1456-1468, 2021 | 172 | 2021 |
Systematic Pan-Cancer Analysis Reveals Immune Cell Interactions in the Tumor Microenvironment FS Varn, Y Wang, DW Mullins, S Fiering, C Cheng Cancer research 77 (6), 1271-1282, 2017 | 168 | 2017 |
Very low mutation burden is a feature of inflamed recurrent glioblastomas responsive to cancer immunotherapy M Gromeier, MC Brown, G Zhang, X Lin, Y Chen, Z Wei, N Beaubier, ... Nature communications 12 (1), 352, 2021 | 116 | 2021 |
Radiotherapy is associated with a deletion signature that contributes to poor outcomes in patients with cancer E Kocakavuk, KJ Anderson, FS Varn, KC Johnson, SB Amin, EP Sulman, ... Nature genetics 53 (7), 1088-1096, 2021 | 115 | 2021 |
Perspective of mesenchymal transformation in glioblastoma Y Kim, FS Varn, SH Park, BW Yoon, HR Park, C Lee, RGW Verhaak, ... Acta neuropathologica communications 9, 1-20, 2021 | 105 | 2021 |
Comparative molecular life history of spontaneous canine and human gliomas SB Amin, KJ Anderson, CE Boudreau, E Martinez-Ledesma, E Kocakavuk, ... Cancer cell 37 (2), 243-257. e7, 2020 | 86 | 2020 |
Therapeutically targeting tumor microenvironment–mediated drug resistance in estrogen receptor–positive breast cancer K Shee, W Yang, JW Hinds, RA Hampsch, FS Varn, NA Traphagen, ... Journal of Experimental Medicine 215 (3), 895-910, 2018 | 74 | 2018 |
Adaptive immunity programmes in breast cancer FS Varn, DW Mullins, H Arias‐Pulido, S Fiering, C Cheng Immunology 150 (1), 25-34, 2017 | 69 | 2017 |
Identification, validation and biological characterisation of novel glioblastoma tumour microenvironment subtypes: implications for precision immunotherapy K White, K Connor, M Meylan, A Bougoüin, M Salvucci, F Bielle, ... Annals of Oncology 34 (3), 300-314, 2023 | 55 | 2023 |
A P53-deficiency gene signature predicts recurrence risk of patients with early-stage lung adenocarcinoma Y Zhao, FS Varn, G Cai, F Xiao, CI Amos, C Cheng Cancer Epidemiology, Biomarkers & Prevention 27 (1), 86-95, 2018 | 53 | 2018 |
Integrative analysis of breast cancer reveals prognostic haematopoietic activity and patient-specific immune response profiles FS Varn, EH Andrews, DW Mullins, C Cheng Nature communications 7 (1), 10248, 2016 | 53 | 2016 |
Computational immune profiling in lung adenocarcinoma reveals reproducible prognostic associations with implications for immunotherapy FS Varn, LJ Tafe, CI Amos, C Cheng Oncoimmunology 7 (6), e1431084, 2018 | 52 | 2018 |
Single-cell RNA sequencing reveals the impact of chromosomal instability on glioblastoma cancer stem cells Y Zhao, R Carter, S Natarajan, FS Varn, DA Compton, C Gawad, C Cheng, ... BMC medical genomics 12, 1-16, 2019 | 50 | 2019 |
Multifactorial deep learning reveals pan-cancer genomic tumor clusters with distinct immunogenomic landscape and response to immunotherapy F Xie, J Zhang, J Wang, A Reuben, W Xu, X Yi, FS Varn, Y Ye, J Cheng, ... Clinical Cancer Research 26 (12), 2908-2920, 2020 | 45 | 2020 |
Genomic characterization of six virus-associated cancers identifies changes in the tumor immune microenvironment and altered genetic programs FS Varn, E Schaafsma, Y Wang, C Cheng Cancer research 78 (22), 6413-6423, 2018 | 40 | 2018 |
A B cell-derived gene expression signature associates with an immunologically active tumor microenvironment and response to immune checkpoint blockade therapy FS Varn, Y Wang, C Cheng OncoImmunology 8 (1), e1513440, 2019 | 27 | 2019 |