| The role of cancer-associated fibroblasts and fibrosis in liver cancer S Affo, LX Yu, RF Schwabe Annual Review of Pathology: Mechanisms of Disease 12 (1), 153-186, 2017 | 629 | 2017 |
| High-yield and high-purity isolation of hepatic stellate cells from normal and fibrotic mouse livers I Mederacke, DH Dapito, S Affò, H Uchinami, RF Schwabe Nature protocols 10 (2), 305-315, 2015 | 540 | 2015 |
| Systemic inflammatory response and serum lipopolysaccharide levels predict multiple organ failure and death in alcoholic hepatitis J Michelena, J Altamirano, JG Abraldes, S Affò, O Morales‐Ibanez, ... Hepatology 62 (3), 762-772, 2015 | 316 | 2015 |
| Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations S Affo, A Nair, F Brundu, A Ravichandra, S Bhattacharjee, M Matsuda, ... Cancer cell 39 (6), 866-882. e11, 2021 | 308 | 2021 |
| Tumor restriction by type I collagen opposes tumor-promoting effects of cancer-associated fibroblasts S Bhattacharjee, F Hamberger, A Ravichandra, M Miller, A Nair, S Affo, ... The Journal of clinical investigation 131 (11), 2024 | 256 | 2024 |
| Hepatocellular carcinoma originates from hepatocytes and not from the progenitor/biliary compartment X Mu, R Español-Suñer, I Mederacke, S Affò, R Manco, C Sempoux, ... The Journal of clinical investigation 125 (10), 3891-3903, 2015 | 230 | 2015 |
| Transcriptome analysis identifies TNF superfamily receptors as potential therapeutic targets in alcoholic hepatitis S Affò, M Dominguez, JJ Lozano, P Sancho-Bru, D Rodrigo-Torres, ... Gut 62 (3), 452-460, 2013 | 211 | 2013 |
| The biliary epithelium gives rise to liver progenitor cells D Rodrigo‐Torres, S Affò, M Coll, O Morales‐Ibanez, C Millán, D Blaya, ... Hepatology 60 (4), 1367-1377, 2014 | 194 | 2014 |
| Opposing roles of hepatic stellate cell subpopulations in hepatocarcinogenesis A Filliol, Y Saito, A Nair, DH Dapito, LX Yu, A Ravichandra, ... Nature 610 (7931), 356-365, 2022 | 187 | 2022 |
| CCL20 mediates lipopolysaccharide induced liver injury and is a potential driver of inflammation and fibrosis in alcoholic hepatitis S Affò, O Morales-Ibanez, D Rodrigo-Torres, J Altamirano, D Blaya, ... Gut 63 (11), 1782-1792, 2014 | 155 | 2014 |
| Human and experimental evidence supporting a role for osteopontin in alcoholic hepatitis O Morales‐Ibanez, M Domínguez, SH Ki, M Marcos, JF Chaves, ... Hepatology 58 (5), 1742-1756, 2013 | 116 | 2013 |
| Integrative miRNA and gene expression profiling analysis of human quiescent hepatic stellate cells M Coll, AE Taghdouini, L Perea, I Mannaerts, M Vila-Casadesús, D Blaya, ... Scientific Reports 5 (1), 11549, 2015 | 98 | 2015 |
| Novel microenvironment-based classification of intrahepatic cholangiocarcinoma with therapeutic implications MA Martin-Serrano, B Kepecs, M Torres-Martin, ER Bramel, PK Haber, ... Gut 72 (4), 736-748, 2023 | 95 | 2023 |
| Cholangiocarcinoma—novel biological insights and therapeutic strategies SI Ilyas, S Affo, L Goyal, A Lamarca, G Sapisochin, JD Yang, GJ Gores Nature Reviews Clinical Oncology 20 (7), 470-486, 2023 | 89 | 2023 |
| MicroRNA‐21 and Dicer are dispensable for hepatic stellate cell activation and the development of liver fibrosis JM Caviglia, J Yan, MK Jang, GY Gwak, S Affo, L Yu, P Olinga, ... Hepatology 67 (6), 2414-2429, 2018 | 86 | 2018 |
| Epithelial transforming growth factor-β signaling does not contribute to liver fibrosis but protects mice from cholangiocarcinoma X Mu, JP Pradere, S Affò, DH Dapito, R Friedman, JH Lefkovitch, ... Gastroenterology 150 (3), 720-733, 2016 | 76 | 2016 |
| Focal adhesion kinase (FAK) promotes cholangiocarcinoma development and progression via YAP activation X Song, H Xu, P Wang, J Wang, S Affo, H Wang, M Xu, B Liang, L Che, ... Journal of hepatology 75 (4), 888-899, 2021 | 69 | 2021 |
| Integrated multiomics reveals glucose use reprogramming and identifies a novel hexokinase in alcoholic hepatitis V Massey, A Parrish, J Argemi, M Moreno, A Mello, M García-Rocha, ... Gastroenterology 160 (5), 1725-1740. e2, 2021 | 53 | 2021 |
| The purinergic P2Y14 receptor links hepatocyte death to hepatic stellate cell activation and fibrogenesis in the liver I Mederacke, A Filliol, S Affo, A Nair, C Hernandez, Q Sun, F Hamberger, ... Science translational medicine 14 (639), eabe5795, 2022 | 50 | 2022 |
| LPS-TLR4 pathway mediates ductular cell expansion in alcoholic hepatitis G Odena, J Chen, JJ Lozano, J Altamirano, D Rodrigo-Torres, S Affo, ... Scientific reports 6 (1), 35610, 2016 | 37 | 2016 |
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