Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation D Wrapp, N Wang, KS Corbett, JA Goldsmith, CL Hsieh, O Abiona, ... Science 367 (6483), 1260-1263, 2020 | 10425 | 2020 |
SARS-CoV-2 mRNA vaccine design enabled by prototype pathogen preparedness KS Corbett, DK Edwards, SR Leist, OM Abiona, S Boyoglu-Barnum, ... Nature, 1-8, 2020 | 1622 | 2020 |
Site-specific glycan analysis of the SARS-CoV-2 spike Y Watanabe, JD Allen, D Wrapp, JS McLellan, M Crispin Science 369 (6501), 330-333, 2020 | 1610 | 2020 |
Structure-based design of prefusion-stabilized SARS-CoV-2 spikes CL Hsieh, JA Goldsmith, JM Schaub, AM DiVenere, HC Kuo, ... Science 369 (6510), 1501-1505, 2020 | 1223 | 2020 |
Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen J Pallesen, N Wang, KS Corbett, D Wrapp, RN Kirchdoerfer, HL Turner, ... Proceedings of the National Academy of Sciences 114 (35), E7348-E7357, 2017 | 1166 | 2017 |
Immunogenicity of a DNA vaccine candidate for COVID-19 TRF Smith, A Patel, S Ramos, D Elwood, X Zhu, J Yan, EN Gary, ... Nature communications 11 (1), 1-13, 2020 | 714 | 2020 |
Structural basis for potent neutralization of betacoronaviruses by single-domain camelid antibodies D Wrapp, D De Vlieger, KS Corbett, GM Torres, N Wang, W Van Breedam, ... Cell, 2020 | 685 | 2020 |
Broad neutralization of SARS-related viruses by human monoclonal antibodies AZ Wec, D Wrapp, AS Herbert, DP Maurer, D Haslwanter, M Sakharkar, ... Science 369 (6504), 731-736, 2020 | 575 | 2020 |
Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis RN Kirchdoerfer, N Wang, J Pallesen, D Wrapp, HL Turner, CA Cottrell, ... Scientific reports 8 (1), 1-11, 2018 | 552 | 2018 |
The neutralizing antibody, LY-CoV555, protects against SARS-CoV-2 infection in nonhuman primates BE Jones, PL Brown-Augsburger, KS Corbett, K Westendorf, J Davies, ... Science translational medicine 13 (593), 2021 | 453 | 2021 |
A highly potent extended half-life antibody as a potential RSV vaccine surrogate for all infants Q Zhu, JS McLellan, NL Kallewaard, ND Ulbrandt, S Palaszynski, J Zhang, ... Science translational medicine 9 (388), 2017 | 318 | 2017 |
Broad and potent activity against SARS-like viruses by an engineered human monoclonal antibody CG Rappazzo, VT Longping, CI Kaku, D Wrapp, M Sakharkar, D Huang, ... Science 371 (6531), 823-829, 2021 | 316 | 2021 |
Prolonged evolution of the human B cell response to SARS-CoV-2 infection M Sakharkar, CG Rappazzo, WF Wieland-Alter, CL Hsieh, D Wrapp, ... Science Immunology 6 (56), 2021 | 188 | 2021 |
Molecular determinants and mechanism for antibody cocktail preventing SARS-CoV-2 escape Z Ku, X Xie, E Davidson, X Ye, H Su, VD Menachery, Y Li, Z Yuan, ... Nature communications 12 (1), 1-13, 2021 | 163 | 2021 |
Infants infected with respiratory syncytial virus generate potent neutralizing antibodies that lack somatic hypermutation E Goodwin, MSA Gilman, D Wrapp, M Chen, JO Ngwuta, SM Moin, P Bai, ... Immunity 48 (2), 339-349. e5, 2018 | 151 | 2018 |
Local computational methods to improve the interpretability and analysis of cryo-EM maps S Kaur, J Gomez-Blanco, AAZ Khalifa, S Adinarayanan, ... Nature Communications 12 (1), 1-12, 2021 | 96 | 2021 |
Potent single-domain antibodies that arrest respiratory syncytial virus fusion protein in its prefusion state I Rossey, MSA Gilman, SC Kabeche, K Sedeyn, D Wrapp, M Kanekiyo, ... Nature communications 8 (1), 1-12, 2017 | 90 | 2017 |
The 3.1-angstrom cryo-electron microscopy structure of the porcine epidemic diarrhea virus spike protein in the prefusion conformation D Wrapp, JS McLellan Journal of virology 93 (23), e00923-19, 2019 | 85 | 2019 |
Cross-reactive coronavirus antibodies with diverse epitope specificities and Fc effector functions AR Shiakolas, KJ Kramer, D Wrapp, SI Richardson, A Schäfer, S Wall, ... Cell Reports Medicine, 100313, 2021 | 72 | 2021 |
Vaccination with prefusion-stabilized respiratory syncytial virus fusion protein induces genetically and antigenically diverse antibody responses M Mukhamedova, D Wrapp, CH Shen, MSA Gilman, TJ Ruckwardt, ... Immunity 54 (4), 769-780. e6, 2021 | 53 | 2021 |