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Joseph Grim
Joseph Grim
Senior Scientist at Mosaic Biosciences
mosaicbio.com의 이메일 확인됨
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Glycopolymer probes of signal transduction
LL Kiessling, JC Grim
Chemical Society Reviews, 4476-4491, 2013
3602013
Extended exposure to stiff microenvironments leads to persistent chromatin remodeling in human mesenchymal stem cells
AR Killaars, JC Grim, CJ Walker, EA Hushka, TE Brown, KS Anseth
Advanced Science 6 (3), 1801483, 2019
2012019
Engineering precision biomaterials for personalized medicine
BA Aguado, JC Grim, AM Rosales, JJ Watson-Capps, KS Anseth
Science translational medicine 10 (424), eaam8645, 2018
2012018
A reversible and repeatable thiol–ene bioconjugation for dynamic patterning of signaling proteins in hydrogels
JC Grim, TE Brown, BA Aguado, DA Chapnick, AL Viert, X Liu, KS Anseth
ACS central science 4 (7), 909-916, 2018
1702018
Nuclear mechanosensing drives chromatin remodelling in persistently activated fibroblasts
CJ Walker, C Crocini, D Ramirez, AR Killaars, JC Grim, BA Aguado, ...
Nature biomedical engineering 5 (12), 1485-1499, 2021
1382021
Thiol-ene and photo-cleavage chemistry for controlled presentation of biomolecules in hydrogels
JC Grim, IA Marozas, KS Anseth
Journal of Controlled Release 219, 95-106, 2015
1252015
Noncarbohydrate glycomimetics and glycoprotein surrogates as DC-SIGN antagonists and agonists
LR Prost, JC Grim, M Tonelli, LL Kiessling
ACS chemical biology 7 (9), 1603-1608, 2012
762012
Secreted factors from proinflammatory macrophages promote an osteoblast-like phenotype in valvular interstitial cells
JC Grim, BA Aguado, BJ Vogt, D Batan, CL Andrichik, ME Schroeder, ...
Arteriosclerosis, thrombosis, and vascular biology 40 (11), e296-e308, 2020
692020
Antigen structure affects cellular routing through DC-SIGN
CM Jarvis, DB Zwick, JC Grim, MM Alam, LR Prost, JC Gardiner, S Park, ...
Proceedings of the National Academy of Sciences 116 (30), 14862-14867, 2019
592019
Transcatheter aortic valve replacements alter circulating serum factors to mediate myofibroblast deactivation
BA Aguado, KB Schuetze, JC Grim, CJ Walker, AC Cox, TL Ceccato, ...
Science translational medicine 11 (509), eaav3233, 2019
562019
Genes that escape X chromosome inactivation modulate sex differences in valve myofibroblasts
BA Aguado, CJ Walker, JC Grim, ME Schroeder, D Batan, BJ Vogt, ...
Circulation 145 (7), 513-530, 2022
542022
Mesenchymal stem cell‐inspired microgel scaffolds to control macrophage polarization
AS Caldwell, VV Rao, AC Golden, DJ Bell, JC Grim, KS Anseth
Bioengineering & Translational Medicine 6 (2), e10217, 2021
302021
Tumor necrosis factor‐α promotes and exacerbates calcification in heart valve myofibroblast populations
A Gonzalez Rodriguez, ME Schroeder, JC Grim, CJ Walker, KF Speckl, ...
The FASEB Journal 35 (3), e21382, 2021
272021
Collagen networks within 3D PEG hydrogels support valvular interstitial cell matrix mineralization
ME Schroeder, AG Rodriguez, KF Speckl, CJ Walker, FS Midekssa, ...
Acta biomaterialia 119, 197-210, 2021
262021
Glycomimetic building blocks: a divergent synthesis of epimers of shikimic acid
JC Grim, KCA Garber, LL Kiessling
Organic letters 13 (15), 3790-3793, 2011
242011
Osteopontin activity modulates sex‐specific calcification in engineered valve tissue mimics
ME Schroeder, D Batan, A Gonzalez Rodriguez, KF Speckl, DK Peters, ...
Bioengineering & translational medicine 8 (1), e10358, 2023
82023
Chemical probes of dendritic cell C-type lectin receptors
JC Grim
The University of Wisconsin-Madison, 2014
12014
Chromatin remodeling controls activation and persistence of aortic valve fibroblasts
C Walker, C Crocini, D Ramirez, A Killaars, J Grim, B Aguado, K Clark, ...
Biophysical Journal 121 (3), 493a, 2022
2022
Synthetic Hydrogels Reveal the Role of the Matrix Microenvironment on Aortic Valve Calcification
ME Schroeder, A Gonzalez Rodriguez, KF Speckl, CJ Walker, ...
Structural Heart 5 (sup1), 73-73, 2021
2021
Engineered Hydrogels as Valve Tissue Mimetics That Recapitulate Sexual Dimorphisms Observed in Calcification and Osteopontin Activity
ME Schroeder, A Gonzalez Rodriquez, K Speckl, DK Peters, CJ Walker, ...
Structural Heart 5 (sup1), 32-32, 2021
2021
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