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Freek Manders
Freek Manders
PhD student, Princes Maxima Center
prinsesmaximacentrum.nl의 이메일 확인됨
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Mutational signature in colorectal cancer caused by genotoxic pks+E. coli
C Pleguezuelos-Manzano, J Puschhof, A Rosendahl Huber, A van Hoeck, ...
Nature 580 (7802), 269-273, 2020
8832020
MutationalPatterns: the one stop shop for the analysis of mutational processes
F Manders, AM Brandsma, J de Kanter, M Verheul, R Oka, ...
BMC genomics 23 (1), 134, 2022
1102022
Antiviral treatment causes a unique mutational signature in cancers of transplantation recipients
JK de Kanter, F Peci, E Bertrums, AR Huber, A van Leeuwen, ...
Cell stem cell 28 (10), 1726-1739. e6, 2021
442021
Mesenchymal tumor organoid models recapitulate rhabdomyosarcoma subtypes
MT Meister, MJA Groot Koerkamp, T de Souza, WB Breunis, ...
EMBO Molecular Medicine 14 (10), e16001, 2022
362022
The dynamics of somatic mutagenesis during life in humans
F Manders, R van Boxtel, S Middelkamp
Frontiers in Aging 2, 802407, 2021
312021
Mutation accumulation and developmental lineages in normal and Down syndrome human fetal haematopoiesis
KAL Hasaart, F Manders, ML van der Hoorn, M Verheul, T Poplonski, ...
Scientific reports 10 (1), 12991, 2020
252020
Mutation signatures of pediatric acute myeloid leukemia and normal blood progenitors associated with differential patient outcomes
AM Brandsma, EJM Bertrums, MJ van Roosmalen, DA Hofman, R Oka, ...
Blood cancer discovery 2 (5), 484-499, 2021
162021
Genomics England Research C
C Pleguezuelos-Manzano, J Puschhof, A Rosendahl Huber, A van Hoeck, ...
Garcia KC, Top J, Willems RJL, Giannakis M, Bonnet R, Quirke P, Meyerson M …, 2020
122020
Increased risk of leukaemia in children with Down syndrome: a somatic evolutionary view
KAL Hasaart, EJM Bertrums, F Manders, BF Goemans, R van Boxtel
Expert reviews in molecular medicine 23, e5, 2021
112021
Human induced pluripotent stem cells display a similar mutation burden as embryonic pluripotent cells in vivo
KAL Hasaart, F Manders, J Ubels, M Verheul, MJ van Roosmalen, ...
Iscience 25 (2), 2022
82022
Comprehensive single-cell genome analysis at nucleotide resolution using the PTA Analysis Toolbox
S Middelkamp, F Manders, F Peci, MJ van Roosmalen, DM González, ...
Cell genomics 3 (9), 2023
72023
Characterizing mutational load and clonal composition of human blood
AR Huber, F Manders, R Oka, R van Boxtel
Journal of Visualized Experiments (JoVE), e59846, 2019
72019
A recurrent somatic missense mutation in GNAS gene identified in familial thyroid follicular cell carcinomas in German longhaired pointer dogs
Y Yu, F Manders, GCM Grinwis, MAM Groenen, RPMA Crooijmans
BMC genomics 23 (1), 669, 2022
32022
DNA mismatch repair controls the mutagenicity of Polymerase ζ-dependent translesion synthesis at methylated guanines
A Tsaalbi-Shtylik, C Mingard, M Räz, R Oka, F Manders, R Van Boxtel, ...
DNA repair 142, 103755, 2024
22024
Corticosteroid‐induced chromatin loop dynamics at the FKBP5 gene
C Wang, F Manders, L Groh, R Oldenkamp, C Logie
Annals of the New York Academy of Sciences 1529 (1), 109-119, 2023
22023
Mutation accumulation in mtDNA of cancers resembles mutagenesis in normal stem cells
F Manders, J van Dinter, R van Boxtel
Iscience 25 (12), 2022
22022
The CTCF anatomy of topologically associating domains
L Nanni, C Wang, F Manders, L Groh, P Haro, R Oldenkamp, S Ceri, ...
bioRxiv, 746610, 2019
22019
Patterns of somatic mutations in normal cells
FM Manders
Utrecht University, 2023
2023
Retrospective Lineage Tracing of Pediatric Acute Myeloid Leukemia Using Single-Cell Whole Genome Sequencing
EJM Bertrums, S Middelkamp, IM van der Werf, F Manders, AM Brandsma, ...
Blood 140 (Supplement 1), 8725-8726, 2022
2022
Mutational Consequences of Hematopoietic Stem Cell Transplantation in Humans
M Belderbos, J de Kanter, F Peci, EJM Bertrums, AR Huber, ...
BONE MARROW TRANSPLANTATION 56 (SUPPL 1), 62-63, 2021
2021
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