Early-onset type-ll diabetes mellitus (MODY4) linked to IPF1 DA Staffers, J Ferrer, WL Clarke, JF Habener Nature genetics 17 (2), 138-139, 1997 | 1261 | 1997 |
A map of open chromatin in human pancreatic islets KJ Gaulton, T Nammo, L Pasquali, JM Simon, PG Giresi, MP Fogarty, ... Nature genetics 42 (3), 255-259, 2010 | 658 | 2010 |
Pancreatic exocrine duct cells give rise to insulin-producing β cells during embryogenesis but not after birth M Solar, C Cardalda, I Houbracken, M Martín, MA Maestro, N De Medts, ... Developmental cell 17 (6), 849-860, 2009 | 603 | 2009 |
Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants L Pasquali, KJ Gaulton, SA Rodríguez-Seguí, L Mularoni, ... Nature genetics 46 (2), 136-143, 2014 | 596 | 2014 |
Macrosomia and Hyperinsulinaemic Hypoglycaemia in Patients with Heterozygous Mutations in the HNF4A Gene ER Pearson, SF Boj, AM Steele, T Barrett, K Stals, JP Shield, S Ellard, ... PLoS medicine 4 (4), e118, 2007 | 541 | 2007 |
Human β cell transcriptome analysis uncovers lncRNAs that are tissue-specific, dynamically regulated, and abnormally expressed in type 2 diabetes I Morán, I Akerman, M Van De Bunt, R Xie, M Benazra, T Nammo, L Arnes, ... Cell metabolism 16 (4), 435-448, 2012 | 500 | 2012 |
Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation A Mahajan, CN Spracklen, W Zhang, MCY Ng, LE Petty, H Kitajima, ... Nature genetics 54 (5), 560-572, 2022 | 488 | 2022 |
Beta cell hubs dictate pancreatic islet responses to glucose NR Johnston, RK Mitchell, E Haythorne, MP Pessoa, F Semplici, J Ferrer, ... Cell metabolism 24 (3), 389-401, 2016 | 476 | 2016 |
Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci KJ Gaulton, T Ferreira, Y Lee, A Raimondo, R Mägi, ME Reschen, ... Nature genetics 47 (12), 1415-1425, 2015 | 436 | 2015 |
A reference map of potential determinants for the human serum metabolome N Bar, T Korem, O Weissbrod, D Zeevi, D Rothschild, S Leviatan, ... Nature 588 (7836), 135-140, 2020 | 364 | 2020 |
GATA6 haploinsufficiency causes pancreatic agenesis in humans HL Allen, SE Flanagan, C Shaw-Smith, E De Franco, I Akerman, ... Nature genetics 44 (1), 20-22, 2012 | 329 | 2012 |
Recessive mutations in a distal PTF1A enhancer cause isolated pancreatic agenesis MN Weedon, I Cebola, AM Patch, SE Flanagan, E De Franco, R Caswell, ... Nature genetics 46 (1), 61-64, 2014 | 323 | 2014 |
A transcription factor regulatory circuit in differentiated pancreatic cells SF Boj, M Párrizas, MA Maestro, J Ferrer Proceedings of the National Academy of Sciences 98 (25), 14481-14486, 2001 | 312 | 2001 |
Human pancreatic islet three-dimensional chromatin architecture provides insights into the genetics of type 2 diabetes I Miguel-Escalada, S Bonàs-Guarch, I Cebola, J Ponsa-Cobas, ... Nature genetics 51 (7), 1137-1148, 2019 | 268 | 2019 |
Transcriptional networks controlling pancreatic development and beta cell function JM Servitja, J Ferrer Diabetologia 47, 597-613, 2004 | 262 | 2004 |
Ins1 Cre knock-in mice for beta cell-specific gene recombination B Thorens, D Tarussio, MA Maestro, M Rovira, E Heikkilä, J Ferrer Diabetologia 58, 558-565, 2015 | 255 | 2015 |
Human pancreatic β cell lncRNAs control cell-specific regulatory networks I Akerman, Z Tu, A Beucher, DMY Rolando, C Sauty-Colace, M Benazra, ... Cell metabolism 25 (2), 400-411, 2017 | 249 | 2017 |
TEAD and YAP regulate the enhancer network of human embryonic pancreatic progenitors I Cebola, SA Rodríguez-Seguí, CHH Cho, J Bessa, M Rovira, M Luengo, ... Nature cell biology 17 (5), 615-626, 2015 | 241 | 2015 |
The miRNA profile of human pancreatic islets and beta-cells and relationship to type 2 diabetes pathogenesis M van de Bunt, KJ Gaulton, L Parts, I Moran, PR Johnson, CM Lindgren, ... PloS one 8 (1), e55272, 2013 | 241 | 2013 |
Adult duct-lining cells can reprogram into β-like cells able to counter repeated cycles of toxin-induced diabetes K Al-Hasani, A Pfeifer, M Courtney, N Ben-Othman, E Gjernes, A Vieira, ... Developmental cell 26 (1), 86-100, 2013 | 237 | 2013 |