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Jorge Ferrer
Jorge Ferrer
Centre for Genomic Regulation – CRG, and Imperial College London
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Early-onset type-ll diabetes mellitus (MODY4) linked to IPF1
DA Staffers, J Ferrer, WL Clarke, JF Habener
Nature genetics 17 (2), 138-139, 1997
12611997
A map of open chromatin in human pancreatic islets
KJ Gaulton, T Nammo, L Pasquali, JM Simon, PG Giresi, MP Fogarty, ...
Nature genetics 42 (3), 255-259, 2010
6582010
Pancreatic exocrine duct cells give rise to insulin-producing β cells during embryogenesis but not after birth
M Solar, C Cardalda, I Houbracken, M Martín, MA Maestro, N De Medts, ...
Developmental cell 17 (6), 849-860, 2009
6032009
Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants
L Pasquali, KJ Gaulton, SA Rodríguez-Seguí, L Mularoni, ...
Nature genetics 46 (2), 136-143, 2014
5962014
Macrosomia and Hyperinsulinaemic Hypoglycaemia in Patients with Heterozygous Mutations in the HNF4A Gene
ER Pearson, SF Boj, AM Steele, T Barrett, K Stals, JP Shield, S Ellard, ...
PLoS medicine 4 (4), e118, 2007
5412007
Human β cell transcriptome analysis uncovers lncRNAs that are tissue-specific, dynamically regulated, and abnormally expressed in type 2 diabetes
I Morán, I Akerman, M Van De Bunt, R Xie, M Benazra, T Nammo, L Arnes, ...
Cell metabolism 16 (4), 435-448, 2012
5002012
Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation
A Mahajan, CN Spracklen, W Zhang, MCY Ng, LE Petty, H Kitajima, ...
Nature genetics 54 (5), 560-572, 2022
4882022
Beta cell hubs dictate pancreatic islet responses to glucose
NR Johnston, RK Mitchell, E Haythorne, MP Pessoa, F Semplici, J Ferrer, ...
Cell metabolism 24 (3), 389-401, 2016
4762016
Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci
KJ Gaulton, T Ferreira, Y Lee, A Raimondo, R Mägi, ME Reschen, ...
Nature genetics 47 (12), 1415-1425, 2015
4362015
A reference map of potential determinants for the human serum metabolome
N Bar, T Korem, O Weissbrod, D Zeevi, D Rothschild, S Leviatan, ...
Nature 588 (7836), 135-140, 2020
3642020
GATA6 haploinsufficiency causes pancreatic agenesis in humans
HL Allen, SE Flanagan, C Shaw-Smith, E De Franco, I Akerman, ...
Nature genetics 44 (1), 20-22, 2012
3292012
Recessive mutations in a distal PTF1A enhancer cause isolated pancreatic agenesis
MN Weedon, I Cebola, AM Patch, SE Flanagan, E De Franco, R Caswell, ...
Nature genetics 46 (1), 61-64, 2014
3232014
A transcription factor regulatory circuit in differentiated pancreatic cells
SF Boj, M Párrizas, MA Maestro, J Ferrer
Proceedings of the National Academy of Sciences 98 (25), 14481-14486, 2001
3122001
Human pancreatic islet three-dimensional chromatin architecture provides insights into the genetics of type 2 diabetes
I Miguel-Escalada, S Bonàs-Guarch, I Cebola, J Ponsa-Cobas, ...
Nature genetics 51 (7), 1137-1148, 2019
2682019
Transcriptional networks controlling pancreatic development and beta cell function
JM Servitja, J Ferrer
Diabetologia 47, 597-613, 2004
2622004
Ins1 Cre knock-in mice for beta cell-specific gene recombination
B Thorens, D Tarussio, MA Maestro, M Rovira, E Heikkilä, J Ferrer
Diabetologia 58, 558-565, 2015
2552015
Human pancreatic β cell lncRNAs control cell-specific regulatory networks
I Akerman, Z Tu, A Beucher, DMY Rolando, C Sauty-Colace, M Benazra, ...
Cell metabolism 25 (2), 400-411, 2017
2492017
TEAD and YAP regulate the enhancer network of human embryonic pancreatic progenitors
I Cebola, SA Rodríguez-Seguí, CHH Cho, J Bessa, M Rovira, M Luengo, ...
Nature cell biology 17 (5), 615-626, 2015
2412015
The miRNA profile of human pancreatic islets and beta-cells and relationship to type 2 diabetes pathogenesis
M van de Bunt, KJ Gaulton, L Parts, I Moran, PR Johnson, CM Lindgren, ...
PloS one 8 (1), e55272, 2013
2412013
Adult duct-lining cells can reprogram into β-like cells able to counter repeated cycles of toxin-induced diabetes
K Al-Hasani, A Pfeifer, M Courtney, N Ben-Othman, E Gjernes, A Vieira, ...
Developmental cell 26 (1), 86-100, 2013
2372013
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