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Rajat M Gupta
Rajat M Gupta
Brigham and Women's Hospital/Harvard Medical School
bwh.harvard.edu의 이메일 확인됨 - 홈페이지
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A TALEN genome-editing system for generating human stem cell-based disease models
Q Ding, YK Lee, EAK Schaefer, DT Peters, A Veres, K Kim, ...
Cell stem cell 12 (2), 238-251, 2013
7222013
Expanding the genetic editing tool kit: ZFNs, TALENs, and CRISPR-Cas9
RM Gupta, K Musunuru
The Journal of clinical investigation 124 (10), 4154-4161, 2014
7112014
COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets
TM Delorey, CGK Ziegler, G Heimberg, R Normand, Y Yang, ...
Nature 595 (7865), 107-113, 2021
7082021
A Genetic Variant Associated with Five Vascular Diseases Is a Distal Regulator of Endothelin-1 Gene Expression
RM Gupta, J Hadaya, A Trehan, SM Zekavat, C Roselli, D Klarin, ...
Cell 170 (3), 522-533. e15, 2017
4472017
Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants
KG Aragam, T Jiang, A Goel, S Kanoni, BN Wolford, DS Atri, EM Weeks, ...
Nature Genetics 54 (12), 1803-1815, 2022
3912022
Single Cell Analysis of the Normal Mouse Aorta Reveals Functionally Distinct Endothelial Cell Populations
AS Kalluri, SK Vellarikkal, ER Edelman, L Nguyen, A Subramanian, ...
Circulation, 2019
2772019
Impaired regulatory T-cell response and enhanced atherosclerosis in the absence of inducible costimulatory molecule
I Gotsman, N Grabie, R Gupta, R Dacosta, M MacConmara, J Lederer, ...
Circulation 114 (19), 2047-2055, 2006
2702006
Dendritic cells genetically engineered to express IL-4 inhibit murine collagen-induced arthritis
Y Morita, J Yang, R Gupta, K Shimizu, EA Shelden, J Endres, JJ Mulé, ...
The Journal of clinical investigation 107 (10), 1275-1284, 2001
2602001
Induced pluripotent stem cells for cardiovascular disease modeling and precision medicine: a scientific statement from the American Heart Association
K Musunuru, F Sheikh, RM Gupta, SR Houser, KO Maher, DJ Milan, ...
Circulation: Genomic and Precision Medicine 11 (1), e000043, 2018
2322018
Leveraging polygenic enrichments of gene features to predict genes underlying complex traits and diseases
EM Weeks, JC Ulirsch, NY Cheng, BL Trippe, RS Fine, J Miao, ...
Nature genetics 55 (8), 1267-1276, 2023
2052023
Deep learning enables genetic analysis of the human thoracic aorta
JP Pirruccello, MD Chaffin, EL Chou, SJ Fleming, H Lin, M Nekoui, ...
Nature genetics 54 (1), 40-51, 2022
1572022
Effector function of resting T cells: activation of synovial fibroblasts
Y Yamamura, R Gupta, Y Morita, X He, R Pai, J Endres, A Freiberg, ...
The Journal of Immunology 166 (4), 2270-2275, 2001
1572001
Myocardial Infarction–Associated SNP at 6p24 Interferes With MEF2 Binding and Associates With PHACTR1 Expression Levels in Human Coronary Arteries
M Beaudoin, RM Gupta, HH Won, KS Lo, R Do, CA Henderson, ...
Arteriosclerosis, thrombosis, and vascular biology 35 (6), 1472-1479, 2015
1082015
Integrative analysis of PRKAG2 cardiomyopathy iPS and microtissue models identifies AMPK as a regulator of metabolism, survival, and fibrosis
JT Hinson, A Chopra, A Lowe, CC Sheng, RM Gupta, R Kuppusamy, ...
Cell reports 17 (12), 3292-3304, 2016
1032016
Molecular interactions between T cells and fibroblast-like synoviocytes: role of membrane tumor necrosis factor-α on cytokine-activated T cells
CN Tran, SK Lundy, PT White, JL Endres, CD Motyl, R Gupta, CM Wilke, ...
The American journal of pathology 171 (5), 1588-1598, 2007
962007
Enhancing literacy in cardiovascular genetics: a scientific statement from the American Heart Association
S Mital, K Musunuru, V Garg, MW Russell, DE Lanfear, RM Gupta, ...
Circulation: Cardiovascular Genetics 9 (5), 448-467, 2016
802016
The influence of the regulatory T lymphocytes on atherosclerosis
I Gotsman, R Gupta, AH Lichtman
Arteriosclerosis, thrombosis, and vascular biology 27 (12), 2493-2495, 2007
712007
Polygenic prediction of preeclampsia and gestational hypertension
MC Honigberg, B Truong, RR Khan, B Xiao, L Bhatta, HMT Vy, ...
Nature medicine 29 (6), 1540-1549, 2023
682023
Genome-edited human pluripotent stem cell–derived macrophages as a model of reverse cholesterol transport—brief report
RM Gupta, TB Meissner, CA Cowan, K Musunuru
Arteriosclerosis, thrombosis, and vascular biology 36 (1), 15-18, 2016
482016
A single-cell and spatial atlas of autopsy tissues reveals pathology and cellular targets of SARS-CoV-2
TM Delorey, CGK Ziegler, G Heimberg, R Normand, Y Yang, ...
bioRxiv, 2021
422021
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