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anne-claude gingras
anne-claude gingras
Lunenfeld-Tanenbaum Research Institute; University of Toronto
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eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation
AC Gingras, B Raught, N Sonenberg
Annual review of biochemistry 68 (1), 913-963, 1999
27891999
The genetic landscape of a cell
M Costanzo, A Baryshnikova, J Bellay, Y Kim, ED Spear, CS Sevier, ...
science 327 (5964), 425-431, 2010
25392010
The CRAPome: a contaminant repository for affinity purification–mass spectrometry data
D Mellacheruvu, Z Wright, AL Couzens, JP Lambert, NA St-Denis, T Li, ...
Nature methods 10 (8), 730-736, 2013
18382013
Histone recognition and large-scale structural analysis of the human bromodomain family
P Filippakopoulos, S Picaud, M Mangos, T Keates, JP Lambert, ...
Cell 149 (1), 214-231, 2012
18322012
Regulation of translation initiation by FRAP/mTOR
AC Gingras, B Raught, N Sonenberg
Genes & development 15 (7), 807-826, 2001
17842001
Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism
AC Gingras, SP Gygi, B Raught, RD Polakiewicz, RT Abraham, ...
Genes & development 13 (11), 1422-1437, 1999
17061999
Sonenberg N.(1994) Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5′-cap function
A Pause, GJ Belsham, AC Gingras, O Donze, TA Lin, JC Lawrence Jr
Nature 371 (6500), 762-767, 1994
16311994
A global genetic interaction network maps a wiring diagram of cellular function
M Costanzo, B VanderSluis, EN Koch, A Baryshnikova, C Pons, G Tan, ...
Science 353 (6306), aaf1420, 2016
13502016
Hierarchical phosphorylation of the translation inhibitor 4E-BP1
AC Gingras, B Raught, SP Gygi, A Niedzwiecka, M Miron, SK Burley, ...
Genes & development 15 (21), 2852-2864, 2001
11702001
4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt (PKB) signaling pathway
AC Gingras, SG Kennedy, MA O’Leary, N Sonenberg, N Hay
Genes & development 12 (4), 502-513, 1998
11491998
Analysis of protein complexes using mass spectrometry
AC Gingras, M Gstaiger, B Raught, R Aebersold
Nature reviews Molecular cell biology 8 (8), 645-654, 2007
9332007
A rapamycin-sensitive signaling pathway contributes to long-term synaptic plasticity in the hippocampus
SJ Tang, G Reis, H Kang, AC Gingras, N Sonenberg, EM Schuman
Proceedings of the National Academy of Sciences 99 (1), 467-472, 2002
8922002
Rapamycin blocks the phosphorylation of 4E‐BP1 and inhibits cap‐dependent initiation of translation.
L Beretta, AC Gingras, YV Svitkin, MN Hall, N Sonenberg
The EMBO journal 15 (3), 658-664, 1996
8801996
Persistence of serum and saliva antibody responses to SARS-CoV-2 spike antigens in COVID-19 patients
B Isho, KT Abe, M Zuo, AJ Jamal, B Rathod, JH Wang, Z Li, G Chao, ...
Science immunology 5 (52), eabe5511, 2020
8722020
Human eukaryotic translation initiation factor 4G (eIF4G) recruits mnk1 to phosphorylate eIF4E
S Pyronnet, H Imataka, AC Gingras, R Fukunaga, T Hunter, N Sonenberg
The EMBO journal, 1999
8571999
Cocrystal structure of the messenger RNA 5′ cap-binding protein (eIF4E) bound to 7-methyl-GDP
J Marcotrigiano, AC Gingras, N Sonenberg, SK Burley
Cell 89 (6), 951-961, 1997
8571997
SAINT: probabilistic scoring of affinity purification–mass spectrometry data
H Choi, B Larsen, ZY Lin, A Breitkreutz, D Mellacheruvu, D Fermin, ZS Qin, ...
Nature methods 8 (1), 70-73, 2011
8562011
The target of rapamycin (TOR) proteins
B Raught, AC Gingras, N Sonenberg
Proceedings of the National Academy of Sciences 98 (13), 7037-7044, 2001
8442001
The mRNA 5′ cap-binding protein eIF4E and control of cell growth
N Sonenberg, AC Gingras
Current opinion in cell biology 10 (2), 268-275, 1998
8111998
A global protein kinase and phosphatase interaction network in yeast
A Breitkreutz, H Choi, JR Sharom, L Boucher, V Neduva, B Larsen, ZY Lin, ...
Science 328 (5981), 1043-1046, 2010
7962010
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