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William A Flavahan
William A Flavahan
Assistant Professor, University of Massachusetts Chan Medical School
umassmed.edu의 이메일 확인됨 - 홈페이지
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Insulator dysfunction and oncogene activation in IDH mutant gliomas
WA Flavahan, Y Drier, BB Liau, SM Gillespie, AS Venteicher, ...
Nature 529 (7584), 110-114, 2016
13822016
Epigenetic plasticity and the hallmarks of cancer
WA Flavahan, E Gaskell, BE Bernstein
Science 357 (6348), eaal2380, 2017
12962017
Periostin secreted by glioblastoma stem cells recruits M2 tumour-associated macrophages and promotes malignant growth
W Zhou, SQ Ke, Z Huang, W Flavahan, X Fang, J Paul, L Wu, AE Sloan, ...
Nature cell biology 17 (2), 170-182, 2015
8962015
Adaptive chromatin remodeling drives glioblastoma stem cell plasticity and drug tolerance
BB Liau, C Sievers, LK Donohue, SM Gillespie, WA Flavahan, TE Miller, ...
Cell stem cell 20 (2), 233-246. e7, 2017
5242017
Brain tumor initiating cells adapt to restricted nutrition through preferential glucose uptake
WA Flavahan, Q Wu, M Hitomi, N Rahim, Y Kim, AE Sloan, RJ Weil, ...
Nature neuroscience 16 (10), 1373-1382, 2013
5182013
Mitochondrial control by DRP1 in brain tumor initiating cells
Q Xie, Q Wu, CM Horbinski, WA Flavahan, K Yang, W Zhou, ...
Nature neuroscience 18 (4), 501-510, 2015
3992015
Preferential iron trafficking characterizes glioblastoma stem-like cells
DL Schonberg, TE Miller, Q Wu, WA Flavahan, NK Das, JS Hale, ...
Cancer cell 28 (4), 441-455, 2015
3232015
Cancer stem cell-specific scavenger receptor CD36 drives glioblastoma progression
JS Hale, B Otvos, M Sinyuk, AG Alvarado, M Hitomi, K Stoltz, Q Wu, ...
Stem cells 32 (7), 1746-1758, 2014
2632014
Cancer stem cell-secreted macrophage migration inhibitory factor stimulates myeloid derived suppressor cell function and facilitates glioblastoma immune evasion
B Otvos, DJ Silver, EE Mulkearns-Hubert, AG Alvarado, SM Turaga, ...
Stem cells 34 (8), 2026-2039, 2016
2452016
Altered chromosomal topology drives oncogenic programs in SDH-deficient GISTs
WA Flavahan, Y Drier, SE Johnstone, ML Hemming, DR Tarjan, E Hegazi, ...
Nature 575 (7781), 229-233, 2019
2282019
Therapeutic targeting of constitutive PARP activation compromises stem cell phenotype and survival of glioblastoma-initiating cells
M Venere, P Hamerlik, Q Wu, RD Rasmussen, LA Song, A Vasanji, ...
Cell Death & Differentiation 21 (2), 258-269, 2014
2102014
Transcription elongation factors represent in vivo cancer dependencies in glioblastoma
TE Miller, BB Liau, LC Wallace, AR Morton, Q Xie, D Dixit, DC Factor, ...
Nature 547 (7663), 355-359, 2017
2042017
Purine synthesis promotes maintenance of brain tumor initiating cells in glioma
X Wang, K Yang, Q Xie, Q Wu, SC Mack, Y Shi, LJY Kim, BC Prager, ...
Nature neuroscience 20 (5), 661-673, 2017
1972017
Differential connexin function enhances self-renewal in glioblastoma
M Hitomi, LP Deleyrolle, EE Mulkearns-Hubert, A Jarrar, M Li, M Sinyuk, ...
Cell reports 11 (7), 1031-1042, 2015
1272015
High-throughput flow cytometry screening reveals a role for junctional adhesion molecule a as a cancer stem cell maintenance factor
JD Lathia, M Li, M Sinyuk, AG Alvarado, WA Flavahan, K Stoltz, ...
Cell reports 6 (1), 117-129, 2014
952014
Imaging remodeling of the actin cytoskeleton in vascular smooth muscle cells after mechanosensitive arteriolar constriction
NA Flavahan, SR Bailey, WA Flavahan, S Mitra, S Flavahan
American Journal of Physiology-Heart and Circulatory Physiology 288 (2 …, 2005
932005
Epigenome editing strategies for the functional annotation of CTCF insulators
DR Tarjan, WA Flavahan, BE Bernstein
Nature communications 10 (1), 4258, 2019
812019
CDC20 maintains tumor initiating cells
Q Xie, Q Wu, SC Mack, K Yang, L Kim, CG Hubert, WA Flavahan, C Chu, ...
Oncotarget 6 (15), 13241, 2015
602015
Salmonella Typhi colonization provokes extensive transcriptional changes aimed at evading host mucosal immune defense during early infection of human intestinal tissue
KP Nickerson, S Senger, Y Zhang, R Lima, S Patel, L Ingano, ...
EBioMedicine 31, 92-109, 2018
572018
Molecular targeting of TRF2 suppresses the growth and tumorigenesis of glioblastoma stem cells
Y Bai, JD Lathia, P Zhang, W Flavahan, JN Rich, MP Mattson
Glia 62 (10), 1687-1698, 2014
522014
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학술자료 1–20