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Gregory Fedorchak
Gregory Fedorchak
Research Associate
cornell.edu의 이메일 확인됨
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Mutant lamins cause nuclear envelope rupture and DNA damage in skeletal muscle cells
AJ Earle, TJ Kirby, GR Fedorchak, P Isermann, J Patel, S Iruvanti, ...
Nature materials 19 (4), 464-473, 2020
2252020
Cellular mechanosensing: getting to the nucleus of it all
GR Fedorchak, A Kaminski, J Lammerding
Progress in biophysics and molecular biology 115 (2-3), 76-92, 2014
2242014
High-throughput microfluidic micropipette aspiration device to probe time-scale dependent nuclear mechanics in intact cells
PM Davidson, GR Fedorchak, S Mondésert-Deveraux, ES Bell, ...
Lab on a Chip 19 (21), 3652-3663, 2019
792019
Diagnosing mild traumatic brain injury using saliva RNA compared to cognitive and balance testing
SD Hicks, C Onks, RY Kim, KJ Zhen, J Loeffert, AC Loeffert, RP Olympia, ...
Clinical and translational medicine 10 (6), e197, 2020
462020
The cellular mastermind (?)—mechanotransduction and the nucleus
A Kaminski, GR Fedorchak, J Lammerding
Progress in molecular biology and translational science 126, 157-203, 2014
462014
Refinement of saliva microRNA biomarkers for sports-related concussion
SD Hicks, C Onks, RY Kim, KJ Zhen, J Loeffert, AC Loeffert, RP Olympia, ...
Journal of sport and health science 12 (3), 369-378, 2023
392023
Saliva RNA biomarkers predict concussion duration and detect symptom recovery: a comparison with balance and cognitive testing
G Fedorchak, A Rangnekar, S Hicks
Journal of Neurology, 2021
372021
Saliva microRNA biomarkers of cumulative concussion
SD Hicks, RP Olympia, C Onks, RY Kim, KJ Zhen, G Fedorchak, S DeVita, ...
International journal of molecular sciences 21 (20), 7758, 2020
242020
Effects of mutant lamins on nucleo-cytoskeletal coupling in Drosophila models of LMNA muscular dystrophy
NM Shaw, JL Rios-Monterrosa, GR Fedorchak, MR Ketterer, GS Coombs, ...
Frontiers in cell and developmental biology 10, 934586, 2022
162022
Cell microharpooning to study nucleo-cytoskeletal coupling
G Fedorchak, J Lammerding
The nuclear envelope: methods and protocols, 241-254, 2016
132016
The lamin A/C Ig-fold undergoes cell density-dependent changes that alter epitope binding
M Wallace, GR Fedorchak, R Agrawal, RM Gilbert, J Patel, S Park, ...
Nucleus 14 (1), 2180206, 2023
62023
Mutant lamins cause mechanically-induced nuclear envelope rupture, DNA damage, and DNA-PK activation in muscle
AJ Earle, TJ Kirby, GR Fedorchak, P Isermann, J Patel, S Iruvanti, ...
BioRxiv, 364778, 2018
62018
The Lamin A/C Ig-fold undergoes cell density-dependent changes that alter epitope accessibility
M Wallace, GR Fedorchak, R Agrawal, RM Gilbert, J Patel, S Park, ...
bioRxiv, 2022.11. 22.517482, 2022
12022
Methods and compositions for treating laminopathies affecting skeletal or cardiac muscle
J Lammerding, TJ Kirby, GR Fedorchak, AJ Earle
US Patent App. 17/274,131, 2021
2021
Mechanically-induced nuclear damage and increased p53 signaling lead to myofiber dysfunction in skeletal muscle laminopathies
TJ Kirby, AJ Earle, GR Fedorchak, P Isermann, J Patel, S Iruvanti, ...
9th UK Nuclear Envelope Disease and Chrmatin Organisation Meeting/3rd …, 2019
2019
High-throughput microfluidic micropipette aspiration device to probe time-scale dependent nuclear mechanics in intact cells
G FEDORCHAK, S MONDÉSERT-DEVERAUX, E BELL, P ISERMANN, ...
Royal Society of Chemistry, 2019
2019
Nuclear envelope protein defects disrupt nucleo-cytoskeletal coupling and nuclear mechanics in muscle.
GR Fedorchak, NM Shaw, LL Wallrath, J Lammerding
MOLECULAR BIOLOGY OF THE CELL 29 (26), 2018
2018
EXPLORING THE ROLE OF NUCLEAR ENVELOPE PROTEINS IN FORCE TRANSMISSION, NUCLEAR MECHANICS, AND MUSCULAR DISEASE
GR Fedorchak
2018
Lamin A/C mutant myonuclei experience nuclear envelope rupture and DNA damage that is reduced upon microtubule stabilization.
TJ Kirby, A Earle, GR Fedorchak, P Isermann, C Brightwell, C Fry, ...
MOLECULAR BIOLOGY OF THE CELL 28, 2017
2017
Lamin mutations linked to muscular disease result in mechanically-induced, progressive nuclear envelope rupture and DNA damage in muscle fibers.
A Earle, TJ Kirby, GR Fedorchak, P Isermann, J Lammerding
MOLECULAR BIOLOGY OF THE CELL 28, 2017
2017
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