| Mendelian randomization study of PCSK9 and HMG-CoA reductase inhibition and cognitive function DB Rosoff, AS Bell, J Jung, J Wagner, LA Mavromatis, FW Lohoff Journal of the American College of Cardiology 80 (7), 653-662, 2022 | 77 | 2022 |
| Multivariate genome-wide analysis of aging-related traits identifies novel loci and new drug targets for healthy aging DB Rosoff, LA Mavromatis, AS Bell, J Wagner, J Jung, RE Marioni, ... Nature aging 3 (8), 1020-1035, 2023 | 29 | 2023 |
| Proprotein convertase subtilisin/kexin type 9 (PCSK9) in the central nervous system AS Bell, J Wagner, DB Rosoff, FW Lohoff Neuroscience & Biobehavioral Reviews 149, 105155, 2023 | 22 | 2023 |
| Multi-omic underpinnings of epigenetic aging and human longevity LA Mavromatis, DB Rosoff, AS Bell, J Jung, J Wagner, FW Lohoff Nature Communications 14 (1), 2236, 2023 | 21 | 2023 |
| Additive effects of stress and alcohol exposure on accelerated epigenetic aging in alcohol use disorder J Jung, DL McCartney, J Wagner, J Yoo, AS Bell, LA Mavromatis, ... Biological psychiatry 93 (4), 331-341, 2023 | 15 | 2023 |
| Comparing the relationships of genetically proxied PCSK9 inhibition with mood disorders, cognition, and dementia between men and women: a drug‐target Mendelian randomization study AS Bell, DB Rosoff, LA Mavromatis, J Jung, J Wagner, FW Lohoff Journal of the American Heart Association 11 (21), e026122, 2022 | 13 | 2022 |
| Assessing the impact of PCSK9 and HMGCR inhibition on liver function: drug-target Mendelian randomization analyses in four ancestries DB Rosoff, AS Bell, J Wagner, LA Mavromatis, A Hamandi, L Park, J Jung, ... Cellular and Molecular Gastroenterology and Hepatology 17 (1), 29-40, 2024 | 10 | 2024 |
| PCSK9 inhibition attenuates alcohol-associated neuronal oxidative stress and cellular injury J Wagner, LM Park, P Mukhopadhyay, C Matyas, E Trojnar, R Damadzic, ... Brain, Behavior, and Immunity 119, 494-506, 2024 | 4 | 2024 |
| PCSK9 Base Editing Therapeutics and Ischemic Stroke J Wagner, AS Bell, FW Lohoff ACS Chemical Neuroscience 13 (23), 3210-3212, 2022 | 4 | 2022 |
| Cholesterol and alcohol AS Bell, EM O’Connell, FW Lohoff Cholesterol, 747-767, 2022 | 4 | 2022 |
| Comparing the relationships of genetically proxied PCSK9 inhibition with mood disorders, cognition, and dementia between men and women: a drug-target mendelian randomization … AS Bell, DB Rosoff, LA Mavromatis, J Jung, J Wagner, FW Lohoff | 2 | |
| Major psychiatric disorders, substance use behaviors, and longevity DB Rosoff, AM Hamandi, AS Bell, LA Mavromatis, LM Park, J Jung, ... JAMA psychiatry 81 (9), 889-901, 2024 | 1 | 2024 |
| Evaluating the Cardiovascular Impact of Genetically Proxied PCSK9 and HMGCR Inhibition in East Asian and European Populations: A Drug-Target Mendelian Randomization Study DB Rosoff, AS Bell, LA Mavromatis, A Hamandi, L Park, J Jung, J Wagner, ... Circulation: Genomic and Precision Medicine 17 (1), e004224, 2024 | 1 | 2024 |
| Multi-Omics Analyses of Cortical Proteome and Single Cell-Type Transcriptome Identifies Novel Drug Targets for Problematic Drinking Behavior and Alcohol Use Disorder D Rosoff, J Wagner, A Bell, L Mavromatis, J Jung, F Lohoff Biological Psychiatry 95 (10), S21, 2024 | | 2024 |
| Comparing the cardiovascular impact of genetically-proxied PCSK9 and HMGCR inhibition between East Asian and European cohorts: a drug-target Mendelian randomization study DB Rosoff, AA Bell, LA Mavromatis, A Hamandi, LA Park, J Jung, ... Circulation, 2023 | | 2023 |
| The Genetics of Alcohol Use Disorder J Wagner, AS Bell, J Jung, FW Lohoff Alcohol and Alcohol-related Diseases, 595-621, 2023 | | 2023 |
| 82. NOVEL THERAPEUTIC DRUG TARGET DISCOVERIES FOR ALCOHOL USE DISORDER AND PROBLEM DRINKING: A MULTI-LEVEL PROTEOME-WIDE MENDELIAN RANDOMIZATION STUDY D Rosoff, J Wagner, A Bell, L Mavromatis, A Hamandi, L Park, J Jung, ... European Neuropsychopharmacology 75, S100-S101, 2023 | | 2023 |
| 62. A MENDELIAN RANDOMIZATION STUDY OF PROPROTEIN CONVERTASE SUBTILISIN KEXIN 9 INHIBITION AND STROKE: EVIDENCE FOR BENEFITS BEYOND LOW-DENSITY LIPOPROTEIN CHOLESTEROL LOWERING L Park, D Rosoff, L Mavromatis, A Bell, A Hamandi, J Jung, J Wagner, ... European Neuropsychopharmacology 75, S89, 2023 | | 2023 |
| Novel Therapeutic Drug Target Discoveries for Alcohol Use Disorder and Problem Drinking: A Multi-Level Proteome-Wide Mendelian Randomization Study D Rosoff, J Wagner, A Bell, L Mavromatis, J Jung, F Lohoff Biological Psychiatry 93 (9), S30, 2023 | | 2023 |
| Novel Underlying Biology and Therapeutic Targets for Alcohol Use Disorder and Problem Drinking Identified Using Proteomics and Mendelian Randomization D Rosoff, J Wagner, A Bell, L Mavromatis, J Jung, F Lohoff NEUROPSYCHOPHARMACOLOGY 47, 447-447, 2022 | | 2022 |