| Effect of fecal microbiota transplantation on 8-week remission in patients with ulcerative colitis: a randomized clinical trial SP Costello, PA Hughes, O Waters, RV Bryant, AD Vincent, P Blatchford, ... Jama 321 (2), 156-164, 2019 | 843 | 2019 |
| The ion channel TRPA1 is required for normal mechanosensation and is modulated by algesic stimuli SM Brierley, PA Hughes, AJ Page, KY Kwan, CM Martin, TA O'Donnell, ... Gastroenterology 137 (6), 2084-2095. e3, 2009 | 318 | 2009 |
| Linaclotide inhibits colonic nociceptors and relieves abdominal pain via guanylate cyclase-C and extracellular cyclic guanosine 3′, 5′-monophosphate J Castro, AM Harrington, PA Hughes, CM Martin, P Ge, CM Shea, H Jin, ... Gastroenterology 145 (6), 1334-1346. e11, 2013 | 316 | 2013 |
| Selective role for TRPV4 ion channels in visceral sensory pathways SM Brierley, AJ Page, PA Hughes, B Adam, T Liebregts, NJ Cooper, ... Gastroenterology 134 (7), 2059-2069, 2008 | 288 | 2008 |
| Sensory neuro-immune interactions differ between irritable bowel syndrome subtypes PA Hughes, AM Harrington, J Castro, T Liebregts, B Adam, DJ Grasby, ... Gut 62 (10), 1456-1465, 2013 | 215 | 2013 |
| Post-inflammatory colonic afferent sensitisation: different subtypes, different pathways and different time courses PA Hughes, SM Brierley, CM Martin, SJH Brookes, DR Linden, ... Gut 58 (10), 1333-1341, 2009 | 197 | 2009 |
| Immune activation in irritable bowel syndrome: can neuroimmune interactions explain symptoms? PA Hughes, H Zola, IA Penttila, AL Blackshaw, JM Andrews, ... Official journal of the American College of Gastroenterology| ACG 108 (7 …, 2013 | 181 | 2013 |
| A novel role for TRPM8 in visceral afferent function AM Harrington, PA Hughes, CM Martin, J Yang, J Castro, NJ Isaacs, ... Pain® 152 (7), 1459-1468, 2011 | 172 | 2011 |
| Colonic immune cells in irritable bowel syndrome: a systematic review and meta‐analysis M Bashashati, S Moossavi, C Cremon, MR Barbaro, S Moraveji, G Talmon, ... Neurogastroenterology & Motility 30 (1), e13192, 2018 | 171 | 2018 |
| TRPA1 contributes to specific mechanically activated currents and sensory neuron mechanical hypersensitivity SM Brierley, J Castro, AM Harrington, PA Hughes, AJ Page, GY Rychkov, ... The Journal of physiology 589 (14), 3575-3593, 2011 | 162 | 2011 |
| Localization and comparative analysis of acid‐sensing ion channel (ASIC1, 2, and 3) mRNA expression in mouse colonic sensory neurons within thoracolumbar dorsal root ganglia PA Hughes, SM Brierley, RL Young, LA Blackshaw Journal of Comparative Neurology 500 (5), 863-875, 2007 | 111 | 2007 |
| Cognitive-behavioural therapy has no effect on disease activity but improves quality of life in subgroups of patients with inflammatory bowel disease: a pilot randomised … A Mikocka-Walus, P Bampton, D Hetzel, P Hughes, A Esterman, ... BMC gastroenterology 15, 1-12, 2015 | 107 | 2015 |
| TRP channels: new targets for visceral pain LA Blackshaw, SM Brierley, PA Hughes Gut 59 (01), 126-135, 2010 | 97 | 2010 |
| Cognitive-behavioural therapy for inflammatory bowel disease: 24-month data from a randomised controlled trial A Mikocka-Walus, P Bampton, D Hetzel, P Hughes, A Esterman, ... International journal of behavioral medicine 24, 127-135, 2017 | 96 | 2017 |
| Deletion of interleukin-6 signal transducer gp130 in small sensory neurons attenuates mechanonociception and down-regulates TRPA1 expression P Malsch, M Andratsch, C Vogl, AS Link, C Alzheimer, SM Brierley, ... Journal of Neuroscience 34 (30), 9845-9856, 2014 | 89 | 2014 |
| Involvement of metabotropic glutamate 5 receptor in visceral pain E Lindström, M Brusberg, PA Hughes, CM Martin, SM Brierley, BD Phillis, ... Pain 137 (2), 295-305, 2008 | 80 | 2008 |
| Acid sensing ion channels 2 and 3 are required for inhibition of visceral nociceptors by benzamil AJ Page, SM Brierley, CM Martin, PA Hughes, LA Blackshaw PAIN® 133 (1-3), 150-160, 2007 | 74 | 2007 |
| Post‐inflammatory modification of colonic afferent mechanosensitivity PA Hughes, SM Brierley, LA Blackshaw Clinical and Experimental Pharmacology and Physiology 36 (10), 1034-1040, 2009 | 67 | 2009 |
| Sprouting of colonic afferent central terminals and increased spinal mitogen‐activated protein kinase expression in a mouse model of chronic visceral hypersensitivity AM Harrington, SM Brierley, N Isaacs, PA Hughes, J Castro, ... Journal of Comparative Neurology 520 (10), 2241-2255, 2012 | 65 | 2012 |
| Immune derived opioidergic inhibition of viscerosensory afferents is decreased in Irritable Bowel Syndrome patients PA Hughes, M Moretta, A Lim, DJ Grasby, D Bird, SM Brierley, T Liebregts, ... Brain, Behavior, and Immunity 42, 191-203, 2014 | 61 | 2014 |
