| The mechanism of action of cyclosporin A and FK506 SL Schreiber, GR Crabtree Immunology today 13 (4), 136-142, 1992 | 2839 | 1992 |
| Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation NA Clipstone, GR Crabtree Nature 357 (6380), 695-697, 1992 | 2174 | 1992 |
| NFAT signaling: choreographing the social lives of cells GR Crabtree, EN Olson Cell 109 (2), S67-S79, 2002 | 1750 | 2002 |
| Proteomic and bioinformatic analysis of mammalian SWI/SNF complexes identifies extensive roles in human malignancy C Kadoch, DC Hargreaves, C Hodges, L Elias, L Ho, J Ranish, ... Nature genetics 45 (6), 592-601, 2013 | 1512 | 2013 |
| Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases J Chung, CJ Kuo, GR Crabtree, J Blenis Cell 69 (7), 1227-1236, 1992 | 1461 | 1992 |
| Contingent genetic regulatory events in T lymphocyte activation GR Crabtree Science 243 (4889), 355-361, 1989 | 1455 | 1989 |
| Nuclear association of a T-cell transcription factor blocked by FK-506 and cyclosporin A WM Flanagan, B Corthésy, RJ Bram, GR Crabtree Nature 352 (6338), 803-807, 1991 | 1392 | 1991 |
| Chromatin remodelling during development L Ho, GR Crabtree Nature 463 (7280), 474-484, 2010 | 1354 | 2010 |
| Identification of a putative regulator of early T cell activation genes JP Shaw, PJ Utz, DB Durand, JJ Toole, EA Emmel, GR Crabtree Science 241 (4862), 202-205, 1988 | 1266 | 1988 |
| lnterleukin-2-mediated elimination of the p27Kipl cyclin-dependent kinase inhibitor prevented by rapamycin J Nourse, E Firpo, WM Flanagan, S Coats, K Polyak, MH Lee, J Massague, ... Nature 372 (6506), 570-573, 1994 | 1229 | 1994 |
| Controlling signal transduction with synthetic ligands DM Spencer, TJ Wandless, SL Schreiber, GR Crabtree Science 262 (5136), 1019-1024, 1993 | 1171 | 1993 |
| MicroRNA-mediated conversion of human fibroblasts to neurons AS Yoo, AX Sun, L Li, A Shcheglovitov, T Portmann, Y Li, C Lee-Messer, ... Nature 476 (7359), 228-231, 2011 | 1147 | 2011 |
| Molecular cloning and expression of cDNAs for the human interleukin-2 receptor WJ Leonard, JM Depper, GR Crabtree, S Rudikoff, J Pumphrey, RJ Robb, ... Nature 311 (5987), 626-631, 1984 | 1094 | 1984 |
| ATP-dependent chromatin remodeling: genetics, genomics and mechanisms DC Hargreaves, GR Crabtree Cell research 21 (3), 396-420, 2011 | 1084 | 2011 |
| Generic signals and specific outcomes: signaling through Ca2+, calcineurin, and NF-AT GR Crabtree Cell 96 (5), 611-614, 1999 | 1040 | 1999 |
| Nuclear export of NF-ATc enhanced by glycogen synthase kinase-3 CR Beals, CM Sheridan, CW Turck, P Gardner, GR Crabtree Science 275 (5308), 1930-1933, 1997 | 1034 | 1997 |
| Purification and biochemical heterogeneity of the mammalian SWI‐SNF complex. W Wang, J Côté, Y Xue, S Zhou, PA Khavari, SR Biggar, C Muchardt, ... The EMBO journal 15 (19), 5370-5382, 1996 | 1034 | 1996 |
| A Brg1 null mutation in the mouse reveals functional differences among mammalian SWI/SNF complexes S Bultman, T Gebuhr, D Yee, C La Mantia, J Nicholson, A Gilliam, ... Molecular cell 6 (6), 1287-1295, 2000 | 989 | 2000 |
| Two distinct signal transmission pathways in T lymphocytes are inhibited by complexes formed between an immunophilin and either FK506 or rapamycin. BE Bierer, PS Mattila, RF Standaert, LA Herzenberg, SJ Burakoff, ... Proceedings of the National Academy of Sciences 87 (23), 9231-9235, 1990 | 959 | 1990 |
| Regulation of interleukin-2 gene enhancer activity by the T cell accessory molecule CD28 JD Fraser, BA Irving, GR Crabtree, A Weiss Science 251 (4991), 313-316, 1991 | 916 | 1991 |