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Ashley Matthew
Ashley Matthew
Virginia Commonwealth University
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Drug design strategies to avoid resistance in direct-acting antivirals and beyond
AN Matthew, F Leidner, GJ Lockbaum, M Henes, J Zephyr, S Hou, ...
Chemical reviews 121 (6), 3238-3270, 2021
582021
Hepatitis C virus NS3/4A protease inhibitors incorporating flexible P2 quinoxalines target drug resistant viral variants
AN Matthew, J Zephyr, CJ Hill, M Jahangir, A Newton, CJ Petropoulos, ...
Journal of medicinal chemistry 60 (13), 5699-5716, 2017
472017
Avoiding drug resistance by substrate envelope-guided design: toward potent and robust HCV NS3/4A protease inhibitors
AN Matthew, J Zephyr, D Nageswara Rao, M Henes, W Kamran, ...
MBio 11 (2), 10.1128/mbio. 00172-20, 2020
202020
Molecular mechanism of resistance in a clinically significant double-mutant variant of HCV NS3/4A protease
AN Matthew, F Leidner, A Newton, CJ Petropoulos, W Huang, A Ali, ...
Structure 26 (10), 1360-1372. e5, 2018
202018
Resistance outside the substrate envelope: hepatitis C NS3/4A protease inhibitors
A Özen, K Prachanronarong, AN Matthew, DI Soumana, CA Schiffer
Critical reviews in biochemistry and molecular biology 54 (1), 11-26, 2019
182019
Quinoxaline-based linear HCV NS3/4A protease inhibitors exhibit potent activity against drug resistant variants
LN Rusere, AN Matthew, GJ Lockbaum, M Jahangir, A Newton, ...
ACS Medicinal Chemistry Letters 9 (7), 691-696, 2018
182018
Discovery of quinoxaline-based p1–p3 macrocyclic ns3/4a protease inhibitors with potent activity against drug-resistant hepatitis C virus variants
D Nageswara Rao, J Zephyr, M Henes, ET Chan, AN Matthew, ...
Journal of medicinal chemistry 64 (16), 11972-11989, 2021
132021
Mavyret: A Pan-Genotypic Combination Therapy for the Treatment of Hepatitis C Infection: Published as part of the Biochemistry series “Biochemistry to Bedside”
AN Matthew, N Kurt Yilmaz, CA Schiffer
Biochemistry 57 (5), 481-482, 2018
112018
Deciphering the molecular mechanism of HCV protease inhibitor Fluorination as a general approach to avoid drug resistance
J Zephyr, DN Rao, SV Vo, M Henes, K Kosovrasti, AN Matthew, ...
Journal of molecular biology 434 (9), 167503, 2022
72022
An overview of the ASU features testbed
J Shah, M Rogers, P Sreevalsan, D Hsiao, A Matthew, A Bhatanagar, ...
Proc. 1990 ASME Computers in Engineering Conference, 233-242, 1990
71990
Avoiding drug resistance by substrate envelope-guided design: toward potent and robust HCV NS3/4A protease inhibitors. mBio 11 (2): e00172-20
AN Matthew, J Zephyr, D Nageswara Rao, M Henes, W Kamran, ...
62020
Evolution of robotic-assisted kidney transplant: successes and barriers to overcome
AN Matthew, LJ Hampton, R Autorino, CS Bhati
Current Opinion in Urology 31 (1), 29-36, 2021
32021
Purification of metal-dependent lysine deacetylases with consistently high activity
TB Toro, RG Painter, RA Haynes, EY Glotser, MR Bratton, JR Bryant, ...
Protein expression and purification 141, 1-6, 2018
32018
The use of low-intensity extracorporeal shockwave therapy in management of erectile dysfunction following prostate cancer treatment: a review of the current literature
AN Matthew, DE Rogers, G Grob, M Blottner, S Kodama, SC Krzastek
Translational Andrology and Urology 12 (6), 1023, 2023
22023
Testosterone deficiency in men with end stage renal disease and kidney transplantation: a narrative review
NA Deebel, AN Matthew, J Loloi, AP Bernstein, N Thirumavalavan, ...
International journal of impotence research, 1-7, 2024
12024
Surgical Management of Extravaginal Testicular Torsion in a 16-Year-Old Male: A Case Report
M Namugosa, KJ Parham, AN Matthew, B Wilson, R Fogg, ED Nelson
Urology, 2024
12024
Paraurethral mass: A case of urethral leiomyoma surgical approach
AN Matthew, LN Siff
International Urogynecology Journal 33 (5), 1351-1352, 2022
12022
Increased Afferent Nerve Firing Is Correlated With the Detection of Bladder Wall Micromotion in a Perfused Ex‐Vivo Porcine Model
RW Fogg, MP Ghatas, B McCormack, M Shields, AN Matthew, G Grob, ...
Neurourology and Urodynamics, 2025
2025
Comparative Neuroexcitation Patterns Using fNIRS in Women With Overactive Bladder
LS Burkett, M Ghatas, H Query, P Daniels, G Grob, A Matthew, D Rogers, ...
Urogynecology, 10.1097, 2024
2024
Perioperative infection prevention during inflatable penile prosthesis surgery: a narrative review
AN Matthew-Onabanjo, AN Matthew, E Famati, V Nguyen, MJ Rogers
Translational Andrology and Urology 13 (8), 1628, 2024
2024
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