Cryo-EM structure of the activated NAIP2-NLRC4 inflammasome reveals nucleated polymerization L Zhang, S Chen, J Ruan, J Wu, AB Tong, Q Yin, Y Li, L David, A Lu, ... Science 350 (6259), 404-409, 2015 | 436 | 2015 |
Structural architecture of the CARMA1/Bcl10/MALT1 signalosome: nucleation-induced filamentous assembly Q Qiao, C Yang, C Zheng, L Fontán, L David, X Yu, C Bracken, M Rosen, ... Molecular cell 51 (6), 766-779, 2013 | 192 | 2013 |
NLRP3 cages revealed by full-length mouse NLRP3 structure control pathway activation L Andreeva, L David, S Rawson, C Shen, T Pasricha, P Pelegrin, H Wu Cell 184 (26), 6299-6312. e22, 2021 | 187 | 2021 |
High-resolution crystal structures of trimeric and rod phycocyanin L David, A Marx, N Adir Journal of molecular biology 405 (1), 201-213, 2011 | 115 | 2011 |
Assembly mechanism of the CARMA1–BCL10–MALT1–TRAF6 signalosome L David, Y Li, J Ma, E Garner, X Zhang, H Wu Proceedings of the National Academy of Sciences 115 (7), 1499-1504, 2018 | 114 | 2018 |
Allophycocyanin trimer stability and functionality are primarily due to polar enhanced hydrophobicity of the phycocyanobilin binding pocket A McGregor, M Klartag, L David, N Adir Journal of molecular biology 384 (2), 406-421, 2008 | 94 | 2008 |
Structural studies show energy transfer within stabilized phycobilisomes independent of the mode of rod–core assembly L David, M Prado, AA Arteni, DA Elmlund, RE Blankenship, N Adir Biochimica et Biophysica Acta (BBA)-Bioenergetics 1837 (3), 385-395, 2014 | 64 | 2014 |
Mechanism of filament formation in UPA-promoted CARD8 and NLRP1 inflammasomes L Robert Hollingsworth, L David, Y Li, AR Griswold, J Ruan, H Sharif, ... Nature communications 12 (1), 189, 2021 | 62 | 2021 |
ROS-dependent S-palmitoylation activates cleaved and intact gasdermin D G Du, LB Healy, L David, C Walker, TJ El-Baba, CA Lutomski, B Goh, ... Nature, 1-3, 2024 | 54 | 2024 |
Homogeneous oligomers of pro-apoptotic BAX reveal structural determinants of mitochondrial membrane permeabilization ZJ Hauseman, EP Harvey, CE Newman, TE Wales, JC Bucci, J Mintseris, ... Molecular cell 79 (1), 68-83. e7, 2020 | 50 | 2020 |
Structural, functional, and mutational analysis of the NblA protein provides insight into possible modes of interaction with the phycobilisome M Dines, E Sendersky, L David, R Schwarz, N Adir Journal of Biological Chemistry 283 (44), 30330-30340, 2008 | 42 | 2008 |
NINJ1 mediates plasma membrane rupture by cutting and releasing membrane disks L David, JP Borges, LR Hollingsworth, A Volchuk, I Jansen, E Garlick, ... Cell 187 (9), 2224-2235. e16, 2024 | 38 | 2024 |
Room temperature biological quantum random walk in phycocyanin nanowires I Eisenberg, S Yochelis, R Ben-Harosh, L David, A Faust, N Even-Dar, ... Physical Chemistry Chemical Physics 16 (23), 11196-11201, 2014 | 32 | 2014 |
Linker proteins enable ultrafast excitation energy transfer in the phycobilisome antenna system of Thermosynechococcus vulcanus C Nganou, L David, N Adir, M Mkandawire Photochemical & Photobiological Sciences 15, 31-44, 2016 | 28 | 2016 |
ROS-dependent palmitoylation is an obligate licensing modification for GSDMD pore formation G Du, LB Healy, L David, C Walker, P Fontana, Y Dong, P Devant, ... BioRxiv, 2023.03. 07.531538, 2023 | 27 | 2023 |
The CBM signalosome: potential therapeutic target for aggressive lymphoma? C Yang, L David, Q Qiao, E Damko, H Wu Cytokine & growth factor reviews 25 (2), 175-183, 2014 | 21 | 2014 |
BCL10 Mutations Define Distinct Dependencies Guiding Precision Therapy for DLBCL M Xia, L David, M Teater, J Gutierrez, X Wang, C Meydan, A Lytle, ... Cancer discovery 12 (8), 1922-1941, 2022 | 17 | 2022 |
Piecing together the phycobilisome A Marx, L David, N Adir The Structural Basis of Biological Energy Generation, 59-76, 2014 | 16 | 2014 |
Gain-of-function mutations in CARD11 promote enhanced aggregation and idiosyncratic signalosome assembly JR Stinson, B Dorjbal, DP McDaniel, L David, H Wu, AL Snow Cellular immunology 353, 104129, 2020 | 13 | 2020 |
Evidence of additional excitation energy transfer pathways in the phycobiliprotein antenna system of Acaryochloris marina AC Nganou, L David, N Adir, D Pouhè, MJ Deen, M Mkandawire Photochemical & photobiological sciences 14 (2), 429-438, 2015 | 9 | 2015 |