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Brian Coventry
Brian Coventry
uw.edu의 이메일 확인됨
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Macromolecular modeling and design in Rosetta: recent methods and frameworks
JK Leman, BD Weitzner, SM Lewis, J Adolf-Bryfogle, N Alam, RF Alford, ...
Nature methods 17 (7), 665-680, 2020
7322020
De novo design of picomolar SARS-CoV-2 miniprotein inhibitors
L Cao, I Goreshnik, B Coventry, JB Case, L Miller, L Kozodoy, RE Chen, ...
Science 370 (6515), 426-431, 2020
6722020
Design of protein-binding proteins from the target structure alone
L Cao, B Coventry, I Goreshnik, B Huang, W Sheffler, JS Park, KM Jude, ...
Nature 605 (7910), 551-560, 2022
3722022
De novo design of luciferases using deep learning
AHW Yeh, C Norn, Y Kipnis, D Tischer, SJ Pellock, D Evans, P Ma, ...
Nature 614 (7949), 774-780, 2023
2732023
Improving de novo protein binder design with deep learning
NR Bennett, B Coventry, I Goreshnik, B Huang, A Allen, D Vafeados, ...
Nature Communications 14 (1), 2625, 2023
1802023
Perturbing the energy landscape for improved packing during computational protein design
JB Maguire, HK Haddox, D Strickland, SF Halabiya, B Coventry, JR Griffin, ...
Proteins: Structure, Function, and Bioinformatics 89 (4), 436-449, 2021
1262021
Protein sequence optimization with a pairwise decomposable penalty for buried unsatisfied hydrogen bonds
B Coventry, D Baker
PLoS computational biology 17 (3), e1008061, 2021
302021
Blueprinting extendable nanomaterials with standardized protein blocks
TF Huddy, Y Hsia, RD Kibler, J Xu, N Bethel, D Nagarajan, R Redler, ...
Nature 627 (8005), 898-904, 2024
272024
De novo design of protein homodimers containing tunable symmetric protein pockets
DR Hicks, MA Kennedy, KA Thompson, M DeWitt, B Coventry, A Kang, ...
Proceedings of the National Academy of Sciences 119 (30), e2113400119, 2022
192022
Robust de novo design of protein binding proteins from target structural information alone
L Cao, B Coventry, I Goreshnik, B Huang, JS Park, KM Jude, I Marković, ...
BioRxiv, 2021.09. 04.459002, 2021
152021
Binding and sensing diverse small molecules using shape-complementary pseudocycles
L An, M Said, L Tran, S Majumder, I Goreshnik, GR Lee, D Juergens, ...
Science 385 (6706), 276-282, 2024
14*2024
Modulation of FGF pathway signaling and vascular differentiation using designed oligomeric assemblies
NI Edman, A Phal, RL Redler, T Schlichthaerle, SR Srivatsan, DD Ehnes, ...
Cell 187 (14), 3726-3740. e43, 2024
142024
Computational design of sequence-specific DNA-binding proteins
CJ Glasscock, R Pecoraro, R McHugh, LA Doyle, W Chen, O Boivin, ...
bioRxiv, 2023
142023
Computational design of a neutralizing antibody with picomolar binding affinity for all concerning SARS-CoV-2 variants
BS Jeong, JS Cha, I Hwang, U Kim, J Adolf-Bryfogle, B Coventry, HS Cho, ...
MAbs 14 (1), 2021601, 2022
142022
Randomized gates eliminate bias in sort‐seq assays
BL Trippe, B Huang, EA DeBenedictis, B Coventry, N Bhattacharya, ...
Protein Science 31 (9), e4401, 2022
132022
Small-molecule binding and sensing with a designed protein family
GR Lee, SJ Pellock, C Norn, D Tischer, J Dauparas, I Anischenko, ...
bioRxiv, 2023.11. 01.565201, 2023
112023
De novo design of picomolar SARS-CoV-2 miniprotein inhibitors. bioRxiv [Preprint]. 2020 Aug 3. DOI: 10.1101/2020.08. 03.234914. Science 23 October 2020: Vol. 370, Issue 6515
L Cao, I Goreshnik, B Coventry, JB Case, L Miller, L Kozodoy, RE Chen, ...
DOI 10, 426-431, 0
8
De novo design of miniprotein antagonists of cytokine storm inducers
B Huang, B Coventry, MT Borowska, DC Arhontoulis, M Exposit, M Abedi, ...
Nature Communications 15 (1), 7064, 2024
72024
Designed endocytosis-inducing proteins degrade targets and amplify signals
B Huang, M Abedi, G Ahn, B Coventry, I Sappington, C Tang, R Wang, ...
Nature, 1-9, 2024
62024
Diffusing protein binders to intrinsically disordered proteins
C Liu, K Wu, H Choi, H Han, X Zhang, JL Watson, S Shijo, AK Bera, ...
bioRxiv, 2024
62024
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학술자료 1–20