ALS genetics, mechanisms, and therapeutics: where are we now? R Mejzini, LL Flynn, IL Pitout, S Fletcher, SD Wilton, PA Akkari Frontiers in neuroscience 13, 1310, 2019 | 816 | 2019 |
The effect of electromagnetic radiation in the mobile phone range on the behaviour of the rat WMU Daniels, IL Pitout, TJO Afullo, MV Mabandla Metabolic brain disease 24, 629-641, 2009 | 104 | 2009 |
ALS genetics, mechanisms, and therapeutics: where are we now? Front Neurosci 13: 1310 R Mejzini, LL Flynn, IL Pitout, S Fletcher, SD Wilton, PA Akkari | 30 | 2019 |
Antisense oligonucleotide-mediated terminal intron retention of the SMN2 transcript LL Flynn, C Mitrpant, IL Pitout, S Fletcher, SD Wilton Molecular Therapy-Nucleic Acids 11, 91-102, 2018 | 27 | 2018 |
Systematic approach to developing splice modulating antisense oligonucleotides MT Aung-Htut, CS McIntosh, KA Ham, IL Pitout, LL Flynn, K Greer, ... International journal of molecular sciences 20 (20), 5030, 2019 | 24 | 2019 |
Antisense-mediated splice intervention to treat human disease: The odyssey continues I Pitout, LL Flynn, SD Wilton, S Fletcher F1000Research 8, 2019 | 19 | 2019 |
DNAzymes: expanding the potential of nucleic acid therapeutics LM Larcher, IL Pitout, NP Keegan, RN Veedu, S Fletcher nucleic acid therapeutics 33 (3), 178-192, 2023 | 18 | 2023 |
ALS genetics, mechanisms, and therapeutics: Where are we now? Front Neurosci. 2019; 13: 1310 R Mejzini, LL Flynn, IL Pitout, S Fletcher, SD Wilton, PA Akkari Přejít k původnímu zdroji... Přejít na PubMed, 2019 | 15 | 2019 |
Single stranded fully modified-phosphorothioate oligonucleotides can induce structured nuclear inclusions, alter nuclear protein localization and disturb the transcriptome in vitro LL Flynn, R Li, IL Pitout, MT Aung-Htut, LM Larcher, JAL Cooper, KL Greer, ... Frontiers in Genetics 13, 791416, 2022 | 12 | 2022 |
Targeted SMN Exon Skipping: A Useful Control to Assess In Vitro and In Vivo Splice-Switching Studies LL Flynn, C Mitrpant, A Adams, IL Pitout, A Stirnweiss, S Fletcher, ... Biomedicines 9 (5), 552, 2021 | 11 | 2021 |
Association of a structural variant within the SQSTM1 gene with amyotrophic lateral sclerosis J Pytte, RS Anderton, LL Flynn, F Theunissen, L Jiang, I Pitout, I James, ... Neurology: Genetics 6 (2), e406, 2020 | 11 | 2020 |
Interaction of modified oligonucleotides with nuclear proteins, formation of novel nuclear structures and sequence-independent effects on RNA processing LL Flynn, R Li, MT Aung-Htut, IL Pitout, JAL Cooper, A Hubbard, L Griffiths, ... BioRxiv, 446773, 2018 | 9 | 2018 |
Characterising splicing defects of ABCA4 variants within exons 13–50 in patient-derived fibroblasts D Huang, JA Thompson, SC Chen, A Adams, I Pitout, A Lima, D Zhang, ... Experimental Eye Research 225, 109276, 2022 | 6 | 2022 |
TDP-43 is a Master Regulator of Paraspeckle Condensation R Hodgson, WP Huang, V Kumar, H An, Z Chalakova, J Rayment, B Ellis, ... | 4 | 2024 |
A Precision Therapy Approach for Retinitis Pigmentosa 11 Using Splice-Switching Antisense Oligonucleotides to Restore the Open Reading Frame of PRPF31 J Grainok, IL Pitout, FK Chen, S McLenachan, RC Heath Jeffery, ... International journal of molecular sciences 25 (6), 3391, 2024 | 3 | 2024 |
Modulation of CNOT3 expression using antisense oligomers to treat retinitis pigmentosa 11 J Grainok, I Pitout, S Wilton, FK Chen, C Mitrpant, S Fletcher Investigative Ophthalmology & Visual Science 62 (8), 1181-1181, 2021 | 2 | 2021 |
Single Stranded Fully Modified-Phosphorothioate Oligonucleotides can Induce Structured Nuclear Inclusions, Alter Nuclear Protein Localization and Disturb the Transcriptome In … LL Flynn, R Li, IL Pitout, MT Aung-Htut, LM Larcher, JAL Cooper, KL Greer, ... Frontiers in Genetics| www. frontiersin. org 13, 2022 | 1 | 2022 |
Modulation of modifiers of pre-mRNA splicing: a therapeutic strategy for amenable inherited diseases I Pitout Murdoch University, 2018 | 1 | 2018 |
Treatment of optic atrophy F Chen, I Pitout, J Grainok, S Utama, K Rice US Patent App. 18/026,388, 2023 | | 2023 |
Upregulation of beclin1-mediated autophagy via antisense oligonucleotides to promote clearance of TDP-43 aggregates in amyotrophic lateral sclerosis cell models. SJ Roldan, S Rea, I Pitout Murdoch University, 2023 | | 2023 |