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Will Macnair
Will Macnair
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Doublet identification in single-cell sequencing data using scDblFinder
PL Germain, A Lun, CG Meixide, W Macnair, MD Robinson
f1000research 10, 979, 2022
5582022
Cell-type-specific cis-eQTLs in eight human brain cell types identify novel risk genes for psychiatric and neurological disorders
J Bryois, D Calini, W Macnair, L Foo, E Urich, W Ortmann, VA Iglesias, ...
Nature neuroscience 25 (8), 1104-1112, 2022
1712022
TGF-β induces oncofetal fibronectin that, in turn, modulates TGF-β superfamily signaling in endothelial cells
E Ventura, M Weller, W Macnair, K Eschbach, C Beisel, C Cordazzo, ...
Journal of cell science 131 (1), jcs209619, 2018
482018
Mapping human adult hippocampal neurogenesis with single-cell transcriptomics: reconciling controversy or fueling the debate?
G Tosoni, D Ayyildiz, J Bryois, W Macnair, CP Fitzsimons, PJ Lucassen, ...
Neuron 111 (11), 1714-1731. e3, 2023
442023
psupertime: supervised pseudotime analysis for time-series single-cell RNA-seq data
W Macnair, R Gupta, M Claassen
Bioinformatics 38 (Supplement_1), i290-i298, 2022
44*2022
Single nuclei RNAseq stratifies multiple sclerosis patients into distinct white matter glial responses
W Macnair, D Calini, E Agirre, J Bryois, S Jäkel, P Kukanja, N Stokar, V Ott, ...
BioRxiv, 2022.04. 06.487263, 2022
242022
SampleQC: robust multivariate, multi-cell type, multi-sample quality control for single-cell data
W Macnair, M Robinson
Genome Biology 24 (1), 23, 2023
162023
Dynamic distribution decomposition for single-cell snapshot time series identifies subpopulations and trajectories during iPSC reprogramming
JP Taylor-King, AN Riseth, W Macnair, M Claassen
PLoS computational biology 16 (1), e1007491, 2020
122020
Doublet identification in single-cell sequencing data using scDblFinder. F1000Research 10, 979
PL Germain, A Lun, W Macnair, MD Robinson
DOI: https://doi. org/10.12688/f1000research 73600, 2021
92021
Negative allosteric modulators of metabotropic glutamate receptor 3 target the stem-like phenotype of glioblastoma
HG Wirsching, M Silginer, E Ventura, W Macnair, I Burghardt, M Claassen, ...
Molecular Therapy-Oncolytics 20, 166-174, 2021
82021
Tree‐ensemble analysis assesses presence of multifurcations in single cell data
W Macnair, L De Vargas Roditi, S Ganscha, M Claassen
Molecular systems biology 15 (3), e8552, 2019
42019
Fenebrutinib, a Bruton’s tyrosine kinase inhibitor, blocks distinct human microglial signaling pathways
J Langlois, S Lange, M Ebeling, W Macnair, R Schmucki, C Li, J DeGeer, ...
Journal of Neuroinflammation 21 (1), 276, 2024
12024
Foamy microglia link oxylipins to disease progression in multiple sclerosis
D van der Vliet, X Di, TM Shamorkina, A Pavlovic, IACM Van der Vliet, ...
bioRxiv, 2024.10. 18.619040, 2024
12024
Unique transcriptional profiles of adult human immature neurons in healthy aging, Alzheimer's disease, and cognitive resilience
G Tosoni, D Ayyildiz, A Penning, S Snoeck, E Santiago-Mujika, ...
bioRxiv, 2025.01. 08.631686, 2025
2025
snRNA-seq stratifies multiple sclerosis patients into distinct white matter glial responses
W Macnair, D Calini, E Agirre, J Bryois, S Jäkel, RS Smith, P Kukanja, ...
Neuron, 2024
2024
Leveraging polygenic enrichments for risk gene prioritisation from GWAS summary statistics
T Dupuis, W Macnair, A Brown, M Ebeling, J Bryois
EUROPEAN JOURNAL OF HUMAN GENETICS 32, 661-661, 2024
2024
Cellular and molecular mapping of human adult hippocampal neurogenesis in Alzheimer’s disease
G Tosoni, A Penning, D Ayyildiz, S Snoeck, SK Poovathingal, K Davie, ...
Alzheimer's & Dementia 19, e074691, 2023
2023
Fenebrutinib, a noncovalent, reversible, Bruton's tyrosine kinase inhibitor, potently blocks neuroinflammation induced by Fcy receptor activation in human microglial systems …
J Langlois, S Lange, J DeGeer, W Macnair, M Ebeling, R Schmucki, ...
MULTIPLE SCLEROSIS JOURNAL 29, 593-594, 2023
2023
Branch point testing and supervised pseudotime inference for single cell data
W Macnair
ETH Zurich, 2019
2019
Current Challenges in Cell-Type Discovery Through Single-Cell Data
L De Vargas Roditi, W Macnair, M Claassen
ITM Web of Conferences 5, 00010, 2015
2015
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