| Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression A Le, CR Cooper, AM Gouw, R Dinavahi, A Maitra, LM Deck, RE Royer, ... Proceedings of the National Academy of Sciences 107 (5), 2037-2042, 2010 | 1592 | 2010 |
| Glucose-independent glutamine metabolism via TCA cycling for proliferation and survival in B cells A Le, AN Lane, M Hamaker, S Bose, A Gouw, J Barbi, T Tsukamoto, ... Cell metabolism 15 (1), 110-121, 2012 | 1223 | 2012 |
| MYC-induced cancer cell energy metabolism and therapeutic opportunities CV Dang, A Le, P Gao Clinical Cancer Research 15 (21), 6479-6483, 2009 | 1072 | 2009 |
| Reprogramming of proline and glutamine metabolism contributes to the proliferative and metabolic responses regulated by oncogenic transcription factor c-MYC W Liu, A Le, C Hancock, AN Lane, CV Dang, TWM Fan, JM Phang Proceedings of the National Academy of Sciences 109 (23), 8983-8988, 2012 | 530 | 2012 |
| Targeted inhibition of tumor-specific glutaminase diminishes cell-autonomous tumorigenesis Y Xiang, ZE Stine, J Xia, Y Lu, RS O’Connor, BJ Altman, AL Hsieh, ... The Journal of clinical investigation 125 (6), 2293-2306, 2015 | 488 | 2015 |
| Quantitative determinants of aerobic glycolysis identify flux through the enzyme GAPDH as a limiting step AA Shestov, X Liu, Z Ser, AA Cluntun, YP Hung, L Huang, D Kim, A Le, ... elife 3, e03342, 2014 | 347 | 2014 |
| Dysregulated metabolism contributes to oncogenesis MD Hirschey, RJ DeBerardinis, AME Diehl, JE Drew, C Frezza, MF Green, ... Seminars in cancer biology 35, S129-S150, 2015 | 328 | 2015 |
| Designing a broad-spectrum integrative approach for cancer prevention and treatment KI Block, C Gyllenhaal, L Lowe, A Amedei, ARMR Amin, A Amin, ... Seminars in cancer biology 35, S276-S304, 2015 | 324 | 2015 |
| Mitochondrial copper depletion suppresses triple-negative breast cancer in mice L Cui, AM Gouw, EL LaGory, S Guo, N Attarwala, Y Tang, J Qi, YS Chen, ... Nature biotechnology 39 (3), 357-367, 2021 | 259 | 2021 |
| Combination therapy with BPTES nanoparticles and metformin targets the metabolic heterogeneity of pancreatic cancer A Elgogary, Q Xu, B Poore, J Alt, SC Zimmermann, L Zhao, J Fu, B Chen, ... Proceedings of the National Academy of Sciences 113 (36), E5328-E5336, 2016 | 234 | 2016 |
| Therapeutic targeting of cancer cell metabolism CV Dang, M Hamaker, P Sun, A Le, P Gao Journal of molecular medicine 89 (3), 205-212, 2011 | 223 | 2011 |
| Glucose metabolism in cancer S Bose, A Le The Heterogeneity of Cancer Metabolism, 3-12, 2018 | 203 | 2018 |
| Therapeutic targeting of the Warburg effect in pancreatic cancer relies on an absence of p53 function NV Rajeshkumar, P Dutta, S Yabuuchi, RF De Wilde, GV Martinez, A Le, ... Cancer research 75 (16), 3355-3364, 2015 | 176 | 2015 |
| Glutamine metabolism in cancer T Li, A Le The Heterogeneity of Cancer Metabolism, 13-32, 2018 | 175 | 2018 |
| Glucose metabolism in cancer: The Warburg effect and beyond S Bose, C Zhang, A Le Adv Exp Med Biol 1311, 3-15, 2021 | 153 | 2021 |
| Discovery of 6-Diazo-5-oxo-l-norleucine (DON) Prodrugs with Enhanced CSF Delivery in Monkeys: A Potential Treatment for Glioblastoma R Rais, A Jancarik, L Tenora, M Nedelcovych, J Alt, J Englert, C Rojas, ... Journal of medicinal chemistry 59 (18), 8621-8633, 2016 | 132 | 2016 |
| Histopathologic and proteogenomic heterogeneity reveals features of clear cell renal cell carcinoma aggressiveness Y Li, TSM Lih, SM Dhanasekaran, R Mannan, L Chen, M Cieslik, Y Wu, ... Cancer Cell 41 (1), 139-163. e17, 2023 | 110 | 2023 |
| Uncovering the role of N-acetyl-aspartyl-glutamate as a glutamate reservoir in cancer T Nguyen, BJ Kirsch, R Asaka, K Nabi, A Quinones, J Tan, MJ Antonio, ... Cell reports 27 (2), 491-501. e6, 2019 | 97 | 2019 |
| Glutamine metabolism in cancer T Li, C Copeland, A Le The Heterogeneity of Cancer Metabolism, 17-38, 2021 | 95 | 2021 |
| Mitogen activated protein kinase activated protein kinase 2 regulates actin polymerization and vascular leak in ventilator associated lung injury M Damarla, E Hasan, A Boueiz, A Le, HH Pae, C Montouchet, T Kolb, ... PloS one 4 (2), e4600, 2009 | 85 | 2009 |