FinnGen provides genetic insights from a well-phenotyped isolated population MI Kurki, J Karjalainen, P Palta, TP Sipilä, K Kristiansson, KM Donner, ... Nature 613 (7944), 508-518, 2023 | 1974 | 2023 |
De novo mutations in schizophrenia implicate synaptic networks M Fromer, AJ Pocklington, DH Kavanagh, HJ Williams, S Dwyer, ... Nature 506 (7487), 179-184, 2014 | 1859 | 2014 |
Analysis of shared heritability in common disorders of the brain Brainstorm Consortium, V Anttila, B Bulik-Sullivan, HK Finucane, ... Science 360 (6395), eaap8757, 2018 | 1488 | 2018 |
Detection and interpretation of shared genetic influences on 42 human traits JK Pickrell, T Berisa, JZ Liu, L Ségurel, JY Tung, DA Hinds Nature genetics 48 (7), 709-717, 2016 | 1246 | 2016 |
Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine P Gormley, V Anttila, BS Winsvold, P Palta, T Esko, TH Pers, KH Farh, ... Nature genetics 48 (8), 856-866, 2016 | 799 | 2016 |
Analysis of shared heritability in common disorders of the brain Brainstorm Consortium Science (New York, NY) 360 (6395), 2018 | 703 | 2018 |
A new highly penetrant form of obesity due to deletions on chromosome 16p11. 2 RG Walters, S Jacquemont, A Valsesia, AJ de Smith, D Martinet, ... Nature 463 (7281), 671-675, 2010 | 626 | 2010 |
Genome-wide meta-analysis identifies new susceptibility loci for migraine V Anttila, BS Winsvold, P Gormley, T Kurth, F Bettella, G McMahon, ... Nature genetics 45 (8), 912-917, 2013 | 487 | 2013 |
Distribution and medical impact of loss-of-function variants in the Finnish founder population ET Lim, P Würtz, AS Havulinna, P Palta, T Tukiainen, K Rehnström, ... PLoS genetics 10 (7), e1004494, 2014 | 477 | 2014 |
Genome-Wide Association Study in Asian Populations Identifies Variants in ETS1 and WDFY4 Associated with Systemic Lupus Erythematosus W Yang, N Shen, DQ Ye, Q Liu, Y Zhang, XX Qian, N Hirankarn, D Ying, ... PLoS genetics 6 (2), e1000841, 2010 | 467 | 2010 |
FinnGen: Unique genetic insights from combining isolated population and national health register data MI Kurki, J Karjalainen, P Palta, TP Sipilä, K Kristiansson, K Donner, ... medrxiv, 2022.03. 03.22271360, 2022 | 441 | 2022 |
Polygenic and clinical risk scores and their impact on age at onset and prediction of cardiometabolic diseases and common cancers N Mars, JT Koskela, P Ripatti, TTJ Kiiskinen, AS Havulinna, JV Lindbohm, ... Nature medicine 26 (4), 549-557, 2020 | 385 | 2020 |
Global Biobank Meta-analysis Initiative: Powering genetic discovery across human disease W Zhou, M Kanai, KHH Wu, H Rasheed, K Tsuo, JB Hirbo, Y Wang, ... Cell Genomics 2 (10), 2022 | 283 | 2022 |
Improved imputation accuracy of rare and low-frequency variants using population-specific high-coverage WGS-based imputation reference panel M Mitt, M Kals, K Pärn, SB Gabriel, ES Lander, A Palotie, S Ripatti, ... European Journal of Human Genetics 25 (7), 869-876, 2017 | 234 | 2017 |
Genetic architecture of human plasma lipidome and its link to cardiovascular disease R Tabassum, JT Rämö, P Ripatti, JT Koskela, M Kurki, J Karjalainen, ... Nature communications 10 (1), 4329, 2019 | 165 | 2019 |
Genetic analysis of obstructive sleep apnoea discovers a strong association with cardiometabolic health S Strausz, S Ruotsalainen, HM Ollila, J Karjalainen, T Kiiskinen, M Reeve, ... European Respiratory Journal 57 (5), 2021 | 142 | 2021 |
The role of polygenic risk and susceptibility genes in breast cancer over the course of life N Mars, E Widén, S Kerminen, T Meretoja, M Pirinen, ... Nature communications 11 (1), 6383, 2020 | 139 | 2020 |
Shared genetic basis for migraine and ischemic stroke: a genome-wide analysis of common variants R Malik, T Freilinger, BS Winsvold, V Anttila, J Vander Heiden, M Traylor, ... Neurology 84 (21), 2132-2145, 2015 | 136 | 2015 |
A comparison of the whole genome approach of MeDIP-seq to the targeted approach of the Infinium HumanMethylation450 BeadChip® for methylome profiling C Clark, P Palta, CJ Joyce, C Scott, E Grundberg, P Deloukas, A Palotie, ... PloS one 7 (11), e50233, 2012 | 116 | 2012 |
Common variant burden contributes to the familial aggregation of migraine in 1,589 families P Gormley, MI Kurki, ME Hiekkala, K Veerapen, P Häppölä, AA Mitchell, ... Neuron 98 (4), 743-753. e4, 2018 | 108 | 2018 |