Mechanism of cisplatin-induced cytotoxicity is correlated to impaired metabolism due to mitochondrial ROS generation YM Choi, HK Kim, W Shim, MA Anwar, JW Kwon, HK Kwon, HJ Kim, ... PloS one 10 (8), e0135083, 2015 | 305 | 2015 |
Doxorubicin-induced necrosis is mediated by poly-(ADP-ribose) polymerase 1 (PARP1) but is independent of p53 HJ Shin, HK Kwon, JH Lee, X Gui, A Achek, JH Kim, S Choi Scientific reports 5 (1), 15798, 2015 | 132 | 2015 |
Discovery of an integrative network of microRNAs and transcriptomics changes for acute kidney injury CG Lee, JG Kim, HJ Kim, HK Kwon, IJ Cho, DW Choi, WH Lee, WD Kim, ... Kidney international 86 (5), 943-953, 2014 | 111 | 2014 |
Doxorubicin induces cytotoxicity through upregulation of perk–dependent ATF3 EJ Park, HK Kwon, YM Choi, HJ Shin, S Choi Public Library of Science 7 (9), e44990, 2012 | 110 | 2012 |
Activating transcription factor 3 represses inflammatory responses by binding to the p65 subunit of NF-κB JW Kwon, HK Kwon, HJ Shin, YM Choi, MA Anwar, S Choi Scientific Reports 5 (1), 14470, 2015 | 93 | 2015 |
Etoposide induced cytotoxicity mediated by ROS and ERK in human kidney proximal tubule cells HJ Shin, HK Kwon, JH Lee, MA Anwar, S Choi Scientific reports 6 (1), 34064, 2016 | 77 | 2016 |
Intracellular Staphylococcus aureus in bone and joint infections: a mechanism of disease recurrence, inflammation, and bone and cartilage destruction KD Alder, I Lee, AM Munger, HK Kwon, MT Morris, SV Cahill, JH Back, ... Bone 141, 115568, 2020 | 72 | 2020 |
Capric acid inhibits NO production and STAT3 activation during LPS-induced osteoclastogenesis EJ Park, SA Kim, YM Choi, HK Kwon, W Shim, G Lee, S Choi PLoS One 6 (11), e27739, 2011 | 51 | 2011 |
TLR4/MD2 specific peptides stalled in vivo LPS-induced immune exacerbation S Park, HJ Shin, M Shah, HY Cho, MA Anwar, A Achek, HK Kwon, B Lee, ... Biomaterials 126, 49-60, 2017 | 50 | 2017 |
Re-appraising the potential of naringin for natural, novel orthopedic biotherapies KE Yu, KD Alder, MT Morris, AM Munger, I Lee, SV Cahill, HK Kwon, ... Therapeutic advances in musculoskeletal disease 12, 1759720X20966135, 2020 | 43 | 2020 |
Structural and functional analysis of cell adhesion and nuclear envelope nano-topography in cell death HK Kwon, JH Lee, HJ Shin, JH Kim, S Choi Scientific reports 5 (1), 15623, 2015 | 41 | 2015 |
ATF3 Plays a Key Role in Kdo2-Lipid A-Induced TLR4-Dependent Gene Expression via NF-κB Activation EY Kim, HY Shin, JY Kim, DG Kim, YM Choi, HK Kwon, DK Rhee, YS Kim, ... PloS one 5 (12), e14181, 2010 | 41 | 2010 |
Recalcitrant methicillin-resistant Staphylococcus aureus infection of bone cells: Intracellular penetration and control strategies K Yu, L Song, HP Kang, HK Kwon, J Back, FY Lee Bone & Joint Research 9 (2), 49-59, 2020 | 39 | 2020 |
A cell-penetrating peptide blocks Toll-like receptor-mediated downstream signaling and ameliorates autoimmune and inflammatory diseases in mice HK Kwon, MC Patra, HJ Shin, X Gui, A Achek, S Panneerselvam, DJ Kim, ... Experimental & Molecular Medicine 51 (4), 1-19, 2019 | 39 | 2019 |
Linear and rationally designed stapled peptides abrogate TLR4 pathway and relieve inflammatory symptoms in rheumatoid arthritis rat model A Achek, M Shah, JY Seo, HK Kwon, X Gui, HJ Shin, EY Cho, BS Lee, ... Journal of medicinal chemistry 62 (14), 6495-6511, 2019 | 34 | 2019 |
Computational insight into the structural organization of full-length Toll-like receptor 4 dimer in a model phospholipid bilayer MC Patra, HK Kwon, M Batool, S Choi Frontiers in Immunology 9, 489, 2018 | 33 | 2018 |
Dual therapeutic targeting of intra-articular inflammation and intracellular bacteria enhances chondroprotection in septic arthritis HK Kwon, I Lee, KE Yu, SV Cahill, KD Alder, S Lee, CM Dussik, JH Back, ... Science Advances 7 (26), eabf2665, 2021 | 28 | 2021 |
Diabetes Aggravates Post-ischaemic Renal Fibrosis through Persistent Activation of TGF-β1 and Shh Signalling DJ Kim, JM Kang, SH Park, HK Kwon, SJ Song, H Moon, SM Kim, JW Seo, ... Scientific reports 7 (1), 16782, 2017 | 28 | 2017 |
Etoposide induces necrosis through p53-mediated antiapoptosis in human kidney proximal tubule cells HK Kwon, HJ Shin, JH Lee, SH Park, MC Kwon, S Panneerselvam, ... Toxicological Sciences 148 (1), 204-219, 2015 | 27 | 2015 |
A peptide derived from the core β-sheet region of TIRAP decoys TLR4 and reduces inflammatory and autoimmune symptoms in murine models A Achek, HK Kwon, MC Patra, M Shah, R Hong, WH Lee, WY Baek, ... EBioMedicine 52, 2020 | 25 | 2020 |