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João Medeiros-Silva
João Medeiros-Silva
Postdoctoral Associate, MIT
mit.edu의 이메일 확인됨
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High-resolution NMR studies of antibiotics in cellular membranes
J Medeiros-Silva, S Jekhmane, AL Paioni, K Gawarecka, M Baldus, ...
Nature communications 9 (1), 3963, 2018
1292018
Teixobactin kills bacteria by a two-pronged attack on the cell envelope
R Shukla, F Lavore, S Maity, MGN Derks, CR Jones, BJA Vermeulen, ...
Nature 608 (7922), 390-396, 2022
1252022
Mode of action of teixobactins in cellular membranes
R Shukla, J Medeiros-Silva, A Parmar, BJA Vermeulen, S Das, AL Paioni, ...
Nature communications 11 (1), 2848, 2020
962020
1H‐Detected Solid‐State NMR Studies of Water‐Inaccessible Proteins In Vitro and In Situ
J Medeiros‐Silva, D Mance, M Daniëls, S Jekhmane, K Houben, ...
Angewandte Chemie International Edition 55 (43), 13606-13610, 2016
962016
Shifts in the selectivity filter dynamics cause modal gating in K+ channels
S Jekhmane, J Medeiros-Silva, J Li, F Kümmerer, C Müller-Hermes, ...
Nature communications 10 (1), 123, 2019
782019
From angstroms to nanometers: measuring interatomic distances by solid-state NMR
AA Shcherbakov, J Medeiros-Silva, N Tran, MD Gelenter, M Hong
Chemical reviews 122 (10), 9848-9879, 2021
512021
Postmodification via thiol-click chemistry yields hydrophilic trityl-nitroxide biradicals for biomolecular high-field dynamic nuclear polarization
W Zhai, A Lucini Paioni, X Cai, S Narasimhan, J Medeiros-Silva, W Zhang, ...
The Journal of Physical Chemistry B 124 (41), 9047-9060, 2020
462020
Supramolecular Organization and Functional Implications of K+ Channel Clusters in Membranes
KM Visscher, J Medeiros‐Silva, D Mance, JP Rodrigues, M Daniëls, ...
Angewandte Chemie International Edition 56 (43), 13222-13227, 2017
402017
pH-and calcium-dependent aromatic network in the SARS-CoV-2 envelope protein
J Medeiros-Silva, NH Somberg, HK Wang, MJ McKay, VS Mandala, ...
Journal of the American Chemical Society 144 (15), 6839-6850, 2022
342022
Design parameters of tissue‐engineering scaffolds at the atomic scale
S Jekhmane, M Prachar, R Pugliese, F Fontana, J Medeiros‐Silva, ...
Angewandte Chemie International Edition 58 (47), 16943-16951, 2019
342019
Structural and functional characterization of protein–lipid interactions of the Salmonella typhimurium melibiose transporter MelB
P Hariharan, E Tikhonova, J Medeiros-Silva, A Jeucken, MV Bogdanov, ...
BMC biology 16, 1-16, 2018
342018
Cell proliferation effects of calix [4] arene derivatives
D Santos, J Medeiros-Silva, S Cegonho, E Alves, F Ramilo-Gomes, ...
Tetrahedron 71 (40), 7593-7599, 2015
292015
Phenanthroline-bis-oxazole ligands for binding and stabilization of G-quadruplexes
J Medeiros-Silva, A Guedin, GF Salgado, JL Mergny, JA Queiroz, ...
Biochimica et Biophysica Acta (BBA)-General Subjects 1861 (5), 1281-1292, 2017
282017
SARS-CoV-2 envelope protein forms clustered pentamers in lipid bilayers
NH Somberg, WW Wu, J Medeiros-Silva, AJ Dregni, H Jo, WF DeGrado, ...
Biochemistry 61 (21), 2280-2294, 2022
272022
Towards the native binding modes of antibiotics that target lipid II
J Medeiros‐Silva, S Jekhmane, E Breukink, M Weingarth
ChemBioChem 20 (14), 1731-1738, 2019
262019
Atomic structure of the open SARS-CoV-2 E viroporin
J Medeiros-Silva, AJ Dregni, NH Somberg, P Duan, M Hong
Science Advances 9 (41), eadi9007, 2023
202023
A distinct mechanism of C-type inactivation in the Kv-like KcsA mutant E71V
A Rohaim, BJA Vermeulen, J Li, F Kümmerer, F Napoli, L Blachowicz, ...
Nature Communications 13 (1), 1574, 2022
182022
Hydrogen bond strength in membrane proteins probed by time-resolved 1H-detected solid-state NMR and MD simulations
J Medeiros-Silva, S Jekhmane, M Baldus, M Weingarth
Solid State Nuclear Magnetic Resonance 87, 80-85, 2017
152017
Molecular basis for the preferential recognition of β1,3‐1,4‐glucans by the family 11 carbohydrate‐binding module from Clostridium thermocellum
DO Ribeiro, A Viegas, VMR Pires, J Medeiros‐Silva, P Bule, W Chai, ...
The FEBS Journal 287 (13), 2723-2743, 2020
132020
The cytoplasmic domain of the SARS-CoV-2 envelope protein assembles into a β-sheet bundle in lipid bilayers
AJ Dregni, MJ McKay, W Surya, M Queralt-Martin, J Medeiros-Silva, ...
Journal of Molecular Biology 435 (5), 167966, 2023
122023
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학술자료 1–20