Modeling familial Alzheimer's disease with induced pluripotent stem cells T Yagi, D Ito, Y Okada, W Akamatsu, Y Nihei, T Yoshizaki, S Yamanaka, ... Human molecular genetics 20 (23), 4530-4539, 2011 | 754 | 2011 |
Mitochondrial dysfunction associated with increased oxidative stress and α-synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain tissue Y Imaizumi, Y Okada, W Akamatsu, M Koike, N Kuzumaki, H Hayakawa, ... Molecular brain 5, 1-13, 2012 | 431 | 2012 |
Nestin-EGFP transgenic mice: visualization of the self-renewal and multipotency of CNS stem cells A Kawaguchi, T Miyata, K Sawamoto, N Takashita, A Murayama, ... Molecular and Cellular Neuroscience 17 (2), 259-273, 2001 | 382 | 2001 |
Increased l1 retrotransposition in the neuronal genome in schizophrenia M Bundo, M Toyoshima, Y Okada, W Akamatsu, J Ueda, ... Neuron 81 (2), 306-313, 2014 | 360 | 2014 |
Mammalian ELAV-like neuronal RNA-binding proteins HuB and HuC promote neuronal development in both the central and the peripheral nervous systems W Akamatsu, HJ Okano, N Osumi, T Inoue, S Nakamura, SI Sakakibara, ... Proceedings of the National Academy of Sciences 96 (17), 9885-9890, 1999 | 291 | 1999 |
The RNA-binding protein HuD regulates neuronal cell identity and maturation W Akamatsu, H Fujihara, T Mitsuhashi, M Yano, S Shibata, Y Hayakawa, ... Proceedings of the National Academy of Sciences 102 (12), 4625-4630, 2005 | 266 | 2005 |
A human Dravet syndrome model from patient induced pluripotent stem cells N Higurashi, T Uchida, C Lossin, Y Misumi, Y Okada, W Akamatsu, ... Molecular brain 6, 1-12, 2013 | 157 | 2013 |
Generation of human melanocytes from induced pluripotent stem cells S Ohta, Y Imaizumi, Y Okada, W Akamatsu, R Kuwahara, M Ohyama, ... PloS one 6 (1), e16182, 2011 | 155 | 2011 |
Increased lysosomal exocytosis induced by lysosomal Ca2+ channel agonists protects human dopaminergic neurons from α-synuclein toxicity T Tsunemi, T Perez-Rosello, Y Ishiguro, A Yoroisaka, S Jeon, K Hamada, ... Journal of Neuroscience 39 (29), 5760-5772, 2019 | 139 | 2019 |
Soluble epoxide hydrolase plays a key role in the pathogenesis of Parkinson’s disease Q Ren, M Ma, J Yang, R Nonaka, A Yamaguchi, K Ishikawa, K Kobayashi, ... Proceedings of the National Academy of Sciences 115 (25), E5815-E5823, 2018 | 132 | 2018 |
The use of induced pluripotent stem cells to reveal pathogenic gene mutations and explore treatments for retinitis pigmentosa T Yoshida, Y Ozawa, K Suzuki, K Yuki, M Ohyama, W Akamatsu, ... Molecular brain 7, 1-11, 2014 | 126 | 2014 |
RNA-binding protein HuD controls insulin translation EK Lee, W Kim, K Tominaga, JL Martindale, X Yang, SS Subaran, ... Molecular cell 45 (6), 826-835, 2012 | 122 | 2012 |
Involvement of ER stress in dysmyelination of Pelizaeus-Merzbacher Disease with PLP1 missense mutations shown by iPSC-derived oligodendrocytes Y Numasawa-Kuroiwa, Y Okada, S Shibata, N Kishi, W Akamatsu, M Shoji, ... Stem cell reports 2 (5), 648-661, 2014 | 117 | 2014 |
Neural stem cells directly differentiated from partially reprogrammed fibroblasts rapidly acquire gliogenic competency T Matsui, M Takano, K Yoshida, S Ono, C Fujisaki, Y Matsuzaki, ... Stem cells 30 (6), 1109-1119, 2012 | 117 | 2012 |
Analysis of induced pluripotent stem cells carrying 22q11. 2 deletion M Toyoshima, W Akamatsu, Y Okada, T Ohnishi, S Balan, Y Hisano, ... Translational psychiatry 6 (11), e934-e934, 2016 | 111 | 2016 |
Establishment of in vitro FUS-associated familial amyotrophic lateral sclerosis model using human induced pluripotent stem cells N Ichiyanagi, K Fujimori, M Yano, C Ishihara-Fujisaki, T Sone, T Akiyama, ... Stem cell reports 6 (4), 496-510, 2016 | 104 | 2016 |
Controlling the regional identity of hPSC-derived neurons to uncover neuronal subtype specificity of neurological disease phenotypes K Imaizumi, T Sone, K Ibata, K Fujimori, M Yuzaki, W Akamatsu, H Okano Stem cell reports 5 (6), 1010-1022, 2015 | 102 | 2015 |
Differentiation of multipotent neural stem cells derived from Rett syndrome patients is biased toward the astrocytic lineage T Andoh-Noda, W Akamatsu, K Miyake, T Matsumoto, R Yamaguchi, ... Molecular brain 8, 1-11, 2015 | 101 | 2015 |
Establishment of induced pluripotent stem cells from centenarians for neurodegenerative disease research T Yagi, A Kosakai, D Ito, Y Okada, W Akamatsu, Y Nihei, A Nabetani, ... PloS one 7 (7), e41572, 2012 | 99 | 2012 |
Variants in saposin D domain of prosaposin gene linked to Parkinson’s disease Y Oji, T Hatano, SI Ueno, M Funayama, K Ishikawa, A Okuzumi, S Noda, ... Brain 143 (4), 1190-1205, 2020 | 97 | 2020 |