Synthesis of epothilones A and B in solid and solution phase KC Nicolaou, N Winssinger, J Pastor, S Ninkovic, F Sarabia, Y He, ... Nature 387 (6630), 268-272, 1997 | 646 | 1997 |
Total syntheses of epothilones A and B via a macrolactonization-based strategy KC Nicolaou, S Ninkovic, F Sarabia, D Vourloumis, Y He, H Vallberg, ... Journal of the American Chemical Society 119 (34), 7974-7991, 1997 | 384 | 1997 |
Designed Epothilones: Combinatorial Synthesis, Tubulin Assembly Properties, abd Cytotoxic Action against Taxol‐Resistant Tumor Cells KC Nicolaou, D Vourloumis, T Li, J Pastor, N Winssinger, Y He, ... Angewandte Chemie International Edition in English 36 (19), 2097-2103, 1997 | 340 | 1997 |
The olefin metathesis approach to epothilone A and its analogues KC Nicolaou, Y He, D Vourloumis, H Vallberg, F Roschangar, F Sarabia, ... Journal of the American Chemical Society 119 (34), 7960-7973, 1997 | 335 | 1997 |
Total synthesis of epothilone A: the olefin metathesis approach Z Yang, Y He, D Vourloumis, H Vallberg, KC Nicolaou Angewandte Chemie International Edition in English 36 (1‐2), 166-168, 1997 | 328 | 1997 |
Design, synthesis and biological evaluations of novel oxindoles as HIV-1 non-nucleoside reverse transcriptase inhibitors. Part I T Jiang, KL Kuhen, K Wolff, H Yin, K Bieza, J Caldwell, B Bursulaya, ... Bioorganic & medicinal chemistry letters 16 (8), 2105-2108, 2006 | 312 | 2006 |
Design, synthesis, and biological evaluations of novel oxindoles as HIV-1 non-nucleoside reverse transcriptase inhibitors. Part 2 T Jiang, KL Kuhen, K Wolff, H Yin, K Bieza, J Caldwell, B Bursulaya, ... Bioorganic & medicinal chemistry letters 16 (8), 2109-2112, 2006 | 256 | 2006 |
An approach to epothilones based on olefin metathesis KC Nicolaou, Y He, D Vourloumis, H Vallberg, Z Yang Angewandte Chemie International Edition in English 35 (20), 2399-2401, 1996 | 187 | 1996 |
Total synthesis of epothilone E and related side-chain modified analogues via a Stille coupling based strategy KC Nicolaou, NP King, MRV Finlay, Y He, F Roschangar, D Vourloumis, ... Bioorganic & medicinal chemistry 7 (5), 665-697, 1999 | 166 | 1999 |
Identification and Initial Structure−Activity Relationships of (R)-5-(2-Azetidinylmethoxy)-2-chloropyridine (ABT-594), a Potent, Orally Active, Non-Opiate Analgesic … MW Holladay, JT Wasicak, NH Lin, Y He, KB Ryther, AW Bannon, ... Journal of medicinal chemistry 41 (4), 407-412, 1998 | 165 | 1998 |
Design and synthesis of 7H-pyrrolo [2, 3-d] pyrimidines as focal adhesion kinase inhibitors. Part 2 HS Choi, Z Wang, W Richmond, X He, K Yang, T Jiang, D Karanewsky, ... Bioorganic & medicinal chemistry letters 16 (10), 2689-2692, 2006 | 164 | 2006 |
Synthesis and biological evaluations of novel benzimidazoles as potential antibacterial agents Y He, J Yang, B Wu, L Risen, EE Swayze Bioorganic & medicinal chemistry letters 14 (5), 1217-1220, 2004 | 151 | 2004 |
2-Piperidin-4-yl-benzimidazoles with broad spectrum antibacterial activities Y He, B Wu, J Yang, D Robinson, L Risen, R Ranken, L Blyn, S Sheng, ... Bioorganic & medicinal chemistry letters 13 (19), 3253-3256, 2003 | 136 | 2003 |
Total Synthesis of the CP Molecules CP‐263,114 and CP‐225,917—Part 1: Synthesis of Key Intermediates and Intelligence Gathering KC Nicolaou, PS Baran, YL Zhong, HS Choi, WH Yoon, Y He, KC Fong Angewandte Chemie International Edition 38 (11), 1669-1675, 1999 | 130 | 1999 |
Total synthesis of epothilone E and analogues with modified side chains through the Stille coupling reaction KC Nicolaou, Y He, F Roschangar, NP King, D Vourloumis, T Li Angewandte Chemie International Edition 37 (1‐2), 84-87, 1998 | 130 | 1998 |
Total Synthesis of the CP Molecules CP‐225,917 and CP‐263,114—Part 2: Evolution of the Final Strategy KC Nicolaou, PS Baran, YL Zhong, KC Fong, Y He, WH Yoon, HS Choi Angewandte Chemie International Edition 38 (11), 1676-1678, 1999 | 110 | 1999 |
Design, synthesis, and biological evaluations of novel quinolones as HIV-1 non-nucleoside reverse transcriptase inhibitors D Ellis, KL Kuhen, B Anaclerio, B Wu, K Wolff, H Yin, B Bursulaya, ... Bioorganic & medicinal chemistry letters 16 (16), 4246-4251, 2006 | 108 | 2006 |
Die Totalsynthese von Epothilon A: der Zugang durch Olefinmetathese Z Yang, Y He, D Vourloumis, H Vallberg, KC Nicolaou Angewandte Chemie 109 (1‐2), 170-172, 1997 | 108 | 1997 |
Synthesis and biological properties of C12, 13-cyclopropylepothilone A and related epothilones KC Nicolaou, MRV Finlay, S Ninkovic, NP King, Y He, T Li, F Sarabia, ... Chemistry & Biology 5 (7), 365-372, 1998 | 106 | 1998 |
3-pyridyloxymethyl heterocyclic ether compounds useful in controlling chemical synaptic transmission NH Lin, Y He, MW Holladay, K Ryther, Y Li US Patent 5,629,325, 1997 | 104* | 1997 |