Cisplatin nephrotoxicity: mechanisms and renoprotective strategies N Pabla, Z Dong Kidney international 73 (9), 994-1007, 2008 | 2131 | 2008 |
ATR-Chk2 signaling in p53 activation and DNA damage response during cisplatin-induced apoptosis N Pabla, S Huang, QS Mi, R Daniel, Z Dong Journal of Biological Chemistry 283 (10), 6572-6583, 2008 | 371 | 2008 |
Checkpoint kinase 1 in DNA damage response and cell cycle regulation M Patil, N Pabla, Z Dong Cellular and molecular life sciences 70, 4009-4021, 2013 | 350 | 2013 |
The copper transporter Ctr1 contributes to cisplatin uptake by renal tubular cells during cisplatin nephrotoxicity N Pabla, RF Murphy, K Liu, Z Dong American Journal of Physiology-Renal Physiology 296 (3), F505-F511, 2009 | 340 | 2009 |
DNA damage response in cisplatin-induced nephrotoxicity S Zhu, N Pabla, C Tang, L He, Z Dong Archives of toxicology 89, 2197-2205, 2015 | 191 | 2015 |
Effects of hydroxyl radical scavenging on cisplatin-induced p53 activation, tubular cell apoptosis and nephrotoxicity M Jiang, Q Wei, N Pabla, G Dong, CY Wang, T Yang, SB Smith, Z Dong Biochemical pharmacology 73 (9), 1499-1510, 2007 | 178 | 2007 |
Inhibition of PKCδ reduces cisplatin-induced nephrotoxicity without blocking chemotherapeutic efficacy in mouse models of cancer N Pabla, G Dong, M Jiang, S Huang, MV Kumar, RO Messing, Z Dong The Journal of clinical investigation 121 (7), 2709-2722, 2011 | 166 | 2011 |
A phosphotyrosine switch regulates organic cation transporters JA Sprowl, SS Ong, AA Gibson, S Hu, G Du, W Lin, L Li, S Bharill, ... Nature communications 7 (1), 10880, 2016 | 136 | 2016 |
MicroRNA-687 induced by hypoxia-inducible factor-1 targets phosphatase and tensin homolog in renal ischemia-reperfusion injury K Bhatt, Q Wei, N Pabla, G Dong, QS Mi, M Liang, C Mei, Z Dong Journal of the American society of nephrology 26 (7), 1588-1596, 2015 | 120 | 2015 |
Mitigation of acute kidney injury by cell-cycle inhibitors that suppress both CDK4/6 and OCT2 functions N Pabla, AA Gibson, M Buege, SS Ong, L Li, S Hu, G Du, JA Sprowl, ... Proceedings of the National Academy of Sciences 112 (16), 5231-5236, 2015 | 110 | 2015 |
hMSH2 recruits ATR to DNA damage sites for activation during DNA damage-induced apoptosis N Pabla, Z Ma, MA McIlhatton, R Fishel, Z Dong Journal of Biological Chemistry 286 (12), 10411-10418, 2011 | 107 | 2011 |
PKC-δ promotes renal tubular cell apoptosis associated with proteinuria X Li, N Pabla, Q Wei, G Dong, RO Messing, CY Wang, Z Dong Journal of the American Society of Nephrology 21 (7), 1115-1124, 2010 | 106 | 2010 |
Nutlin-3 protects kidney cells during cisplatin therapy by suppressing Bax/Bak activation M Jiang, N Pabla, RF Murphy, T Yang, XM Yin, K Degenhardt, E White, ... Journal of Biological Chemistry 282 (4), 2636-2645, 2007 | 98 | 2007 |
Expression, subcellular localization, and regulation of sigma receptor in retinal muller cells G Jiang, B Mysona, Y Dun, JP Gnana-Prakasam, N Pabla, W Li, Z Dong, ... Investigative ophthalmology & visual science 47 (12), 5576-5582, 2006 | 83 | 2006 |
Curtailing side effects in chemotherapy: a tale of PKCδ in cisplatin treatment N Pabla, Z Dong Oncotarget 3 (1), 107, 2012 | 81 | 2012 |
Checkpoint kinase 1 (Chk1)-short is a splice variant and endogenous inhibitor of Chk1 that regulates cell cycle and DNA damage checkpoints N Pabla, K Bhatt, Z Dong Proceedings of the National Academy of Sciences 109 (1), 197-202, 2012 | 78 | 2012 |
Cisplatin-induced renal injury is independently mediated by OCT2 and p53 JA Sprowl, CS Lancaster, N Pabla, E Hermann, AM Kosloske, AA Gibson, ... Clinical Cancer Research 20 (15), 4026-4035, 2014 | 74 | 2014 |
Neuronal uptake transporters contribute to oxaliplatin neurotoxicity in mice KM Huang, AF Leblanc, ME Uddin, JY Kim, M Chen, ED Eisenmann, ... The Journal of clinical investigation 130 (9), 4601-4606, 2020 | 61 | 2020 |
Identification of OAT1/OAT3 as contributors to cisplatin toxicity S Hu, AF Leblanc, AA Gibson, KW Hong, JY Kim, LJ Janke, L Li, ... Clinical and translational science 10 (5), 412-420, 2017 | 61 | 2017 |
Caspase-mediated cleavage of ATM during cisplatin-induced tubular cell apoptosis: inactivation of its kinase activity toward p53 J Wang, N Pabla, CY Wang, W Wang, PV Schoenlein, Z Dong American Journal of Physiology-Renal Physiology 291 (6), F1300-F1307, 2006 | 61 | 2006 |