Vitamin B3 modulates mitochondrial vulnerability and prevents glaucoma in aged mice PA Williams, JM Harder, NE Foxworth, KE Cochran, VM Philip, V Porciatti, ... Science 355 (6326), 756-760, 2017 | 563 | 2017 |
Neuroinflammation in glaucoma: A new opportunity PA Williams, N Marsh-Armstrong, GR Howell, T Lasker, II on Astrocytes, ... Experimental eye research 157, 20-27, 2017 | 244 | 2017 |
Inhibition of the classical pathway of the complement cascade prevents early dendritic and synaptic degeneration in glaucoma PA Williams, JR Tribble, KW Pepper, SD Cross, BP Morgan, JE Morgan, ... Molecular neurodegeneration 11, 1-13, 2016 | 184 | 2016 |
Improvement in inner retinal function in glaucoma with nicotinamide (vitamin B3) supplementation: A crossover randomized clinical trial F Hui, J Tang, PA Williams, MB McGuinness, X Hadoux, RJ Casson, ... Clinical & Experimental Ophthalmology 48 (7), 903-914, 2020 | 183 | 2020 |
A multiethnic genome-wide association study of primary open-angle glaucoma identifies novel risk loci H Choquet, S Paylakhi, SC Kneeland, KK Thai, TJ Hoffmann, J Yin, ... Nature Communications 9 (1), 2278, 2018 | 182 | 2018 |
Nicotinamide provides neuroprotection in glaucoma by protecting against mitochondrial and metabolic dysfunction JR Tribble, A Otmani, S Sun, SA Ellis, G Cimaglia, R Vohra, M Jöe, ... Redox biology 43, 101988, 2021 | 141 | 2021 |
Retinal ganglion cell dendritic atrophy in DBA/2J glaucoma PA Williams, GR Howell, JM Barbay, CE Braine, GL Sousa, SWM John, ... PloS one 8 (8), e72282, 2013 | 116 | 2013 |
Opa1 deficiency in a mouse model of dominant optic atrophy leads to retinal ganglion cell dendropathy PA Williams, JE Morgan, M Votruba Brain 133 (10), 2942-2951, 2010 | 116 | 2010 |
Retinal ganglion cell dendritic degeneration in a mouse model of Alzheimer's disease PA Williams, RA Thirgood, H Oliphant, A Frizzati, E Littlewood, M Votruba, ... Neurobiology of aging 34 (7), 1799-1806, 2013 | 113 | 2013 |
Early immune responses are independent of RGC dysfunction in glaucoma with complement component C3 being protective JM Harder, CE Braine, PA Williams, X Zhu, KH MacNicoll, GL Sousa, ... Proceedings of the National Academy of Sciences 114 (19), E3839-E3848, 2017 | 107 | 2017 |
Nicotinamide and WLDS act together to prevent neurodegeneration in glaucoma PA Williams, JM Harder, NE Foxworth, BH Cardozo, KE Cochran Frontiers in Neuroscience 11, 232, 2017 | 101 | 2017 |
Nicotinamide and pyruvate for neuroenhancement in open-angle glaucoma: a phase 2 randomized clinical trial CG De Moraes, SWM John, PA Williams, DM Blumberg, GA Cioffi, ... JAMA ophthalmology 140 (1), 11-18, 2022 | 97 | 2022 |
Opa1 is essential for retinal ganglion cell synaptic architecture and connectivity PA Williams, M Piechota, C von Ruhland, E Taylor, JE Morgan, M Votruba Brain 135 (2), 493-505, 2012 | 97 | 2012 |
Retinal energy metabolism in health and glaucoma RJ Casson, G Chidlow, JG Crowston, PA Williams, JPM Wood Progress in Retinal and Eye Research 81, 100881, 2021 | 93 | 2021 |
Using genetic mouse models to gain insight into glaucoma: Past results and future possibilities KA Fernandes, JM Harder, PA Williams, RL Rausch, AE Kiernan, KS Nair, ... Experimental eye research 141, 42-56, 2015 | 89 | 2015 |
Glaucoma as a metabolic optic neuropathy: making the case for nicotinamide treatment in glaucoma PA Williams, JM Harder, SWM John Journal of glaucoma 26 (12), 1161-1168, 2017 | 88 | 2017 |
Disturbed glucose and pyruvate metabolism in glaucoma with neuroprotection by pyruvate or rapamycin JM Harder, C Guymer, JPM Wood, E Daskalaki, G Chidlow, C Zhang, ... Proceedings of the National Academy of Sciences 117 (52), 33619-33627, 2020 | 83 | 2020 |
Nicotinamide treatment robustly protects from inherited mouse glaucoma PA Williams, JM Harder, BH Cardozo, NE Foxworth, SWM John Communicative & Integrative Biology 11 (1), e1356956, 2018 | 77 | 2018 |
Protrudin functions from the endoplasmic reticulum to support axon regeneration in the adult CNS V Petrova, CS Pearson, J Ching, JR Tribble, AG Solano, Y Yang, FM Love, ... Nature Communications 11 (1), 1-15, 2020 | 64 | 2020 |
A miniature, fiber-coupled, wireless, deep-brain optogenetic stimulator ST Lee, PA Williams, CE Braine, DT Lin, SWM John, PP Irazoqui IEEE Transactions on Neural Systems and Rehabilitation Engineering 23 (4 …, 2015 | 64 | 2015 |