Neurons derived from sporadic Alzheimer’s disease iPSCs reveal elevated TAU hyperphosphorylation, increased amyloid levels, and GSK3B activation A Ochalek, B Mihalik, HX Avci, A Chandrasekaran, A Téglási, I Bock, ... Alzheimer's research & therapy 9, 1-19, 2017 | 213 | 2017 |
Functional differences in yeast protein disulfide isomerases P Nørgaard, V Westphal, C Tachibana, L Alsøe, B Holst, JR Winther The Journal of cell biology 152 (3), 553-562, 2001 | 171 | 2001 |
Transient p53 suppression increases reprogramming of human fibroblasts without affecting apoptosis and DNA damage MA Rasmussen, B Holst, Z Tümer, MG Johnsen, S Zhou, TC Stummann, ... Stem cell reports 3 (3), 404-413, 2014 | 142 | 2014 |
GUP1 and its close homologue GUP2, encoding multimembrane‐spanning proteins involved in active glycerol uptake in Saccharomyces cerevisiae B Holst, C Lunde, F Lages, R Oliveira, C Lucas, MC Kielland‐Brandt Molecular microbiology 37 (1), 108-124, 2000 | 133 | 2000 |
Competition between folding and glycosylation in the endoplasmic reticulum. B Holst, AW Bruun, MC Kielland‐Brandt, JR Winther The EMBO Journal 15 (14), 3538-3546, 1996 | 121 | 1996 |
Active site mutations in yeast protein disulfide isomerase cause dithiothreitol sensitivity and a reduced rate of protein folding in the endoplasmic reticulum B Holst, C Tachibana, JR Winther The Journal of cell biology 138 (6), 1229-1238, 1997 | 110 | 1997 |
Patient iPSC-derived neurons for disease modeling of frontotemporal dementia with mutation in CHMP2B Y Zhang, B Schmid, NK Nikolaisen, MA Rasmussen, BI Aldana, M Agger, ... Stem cell reports 8 (3), 648-658, 2017 | 86 | 2017 |
Rapid establishment of the European Bank for induced Pluripotent Stem Cells (EBiSC)-the hot start experience PA De Sousa, R Steeg, E Wachter, K Bruce, J King, M Hoeve, S Khadun, ... Stem Cell Research 20, 105-114, 2017 | 66 | 2017 |
The recognition of adsorbed and denatured proteins of different topographies by β2 integrins and effects on leukocyte adhesion and activation T Brevig, B Holst, Z Ademovic, N Rozlosnik, JH Røhrmann, NB Larsen, ... Biomaterials 26 (16), 3039-3053, 2005 | 51 | 2005 |
Reproduction of European Eel in Aquaculture (REEL): consolidation and new production methods J Tomkiewicz, L Tybjerg, J Støttrup, F McEvoy, P Ravn, SR Sørensen, ... DTU Aqua, 2012 | 45 | 2012 |
Generation of a gene-corrected isogenic control hiPSC line derived from a familial Alzheimer's disease patient carrying a L150P mutation in presenilin 1 A Poon, B Schmid, C Pires, TT Nielsen, LE Hjermind, JE Nielsen, B Holst, ... Stem cell research 17 (3), 466-469, 2016 | 43 | 2016 |
Synthesis of a carboxamide linked T * T dimer and its incorporation in oligonucleotides A Chur, B Holst, O Dahl, P Valentin-Hansen, EB Pedersen Nucleic acids research 21 (22), 5179-5183, 1993 | 41 | 1993 |
Generation of a set of isogenic, gene-edited iPSC lines homozygous for all main APOE variants and an APOE knock-out line B Schmid, KR Prehn, N Nimsanor, BIA Garcia, U Poulsen, I Jørring, ... Stem Cell Research 34, 101349, 2019 | 40 | 2019 |
Generation of an isogenic, gene-corrected control cell line of the spinocerebellar ataxia type 2 patient-derived iPSC line H196 AG Marthaler, B Schmid, A Tubsuwan, UB Poulsen, AF Engelbrecht, ... Stem cell research 16 (1), 162-165, 2016 | 38 | 2016 |
cAMP-CRP activator complex and the CytR repressor protein bind co-operatively to the cytRP promoter in Escherichia coli and CytR antagonizes the cAMP-CRP-induced DNA bend H Pedersen, L Søgaard-Andersen, B Holst, P Gerlach, E Bremer, ... Journal of molecular biology 227 (2), 396-406, 1992 | 37 | 1992 |
EBiSC best practice: how to ensure optimal generation, qualification, and distribution of iPSC lines R Steeg, SC Mueller, N Mah, B Holst, A Cabrera-Socorro, GN Stacey, ... Stem Cell Reports 16 (8), 1853-1867, 2021 | 36 | 2021 |
Low‐molecular‐weight carbohydrate Pentaisomaltose may replace dimethyl sulfoxide as a safer cryoprotectant for cryopreservation of peripheral blood stem cells JD Svalgaard, EK Haastrup, K Reckzeh, B Holst, PV Glovinski, JS Gørløv, ... Transfusion 56 (5), 1088-1095, 2016 | 36 | 2016 |
A novel human pluripotent stem cell-based assay to predict developmental toxicity K Lauschke, AK Rosenmai, I Meiser, JC Neubauer, K Schmidt, ... Archives of Toxicology 94, 3831-3846, 2020 | 35 | 2020 |
The method of surface PEGylation influences leukocyte adhesion and activation Z Ademovic, B Holst, RA Kahn, I Jørring, T Brevig, J Wei, X Hou, ... Journal of Materials Science: Materials in Medicine 17, 203-211, 2006 | 34 | 2006 |
CRP/cAMP‐ and CytR‐regulated promoters in Escherichia coli K12: the cdd promoter P Valentin‐Hansen, B Holst, J Josephsen, K Hammer, B Albrechtsen Molecular microbiology 3 (10), 1385-1390, 1989 | 32 | 1989 |