| Cpf1 is a single RNA-guided endonuclease of a class 2 CRISPR-Cas system B Zetsche, JS Gootenberg, OO Abudayyeh, IM Slaymaker, KS Makarova, ... cell 163 (3), 759-771, 2015 | 5122 | 2015 |
| Nucleic acid detection with CRISPR-Cas13a/C2c2 JS Gootenberg, OO Abudayyeh, JW Lee, P Essletzbichler, AJ Dy, J Joung, ... Science 356 (6336), 438-442, 2017 | 3289 | 2017 |
| Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex S Konermann, MD Brigham, AE Trevino, J Joung, OO Abudayyeh, ... Nature 517 (7536), 583-588, 2015 | 3151 | 2015 |
| C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector OO Abudayyeh, JS Gootenberg, S Konermann, J Joung, IM Slaymaker, ... Science 353 (6299), aaf5573, 2016 | 2395 | 2016 |
| Multiplexed and portable nucleic acid detection platform with Cas13, Cas12a, and Csm6 JS Gootenberg, OO Abudayyeh, MJ Kellner, J Joung, JJ Collins, F Zhang Science 360 (6387), 439-444, 2018 | 2276 | 2018 |
| RNA targeting with CRISPR–Cas13 OO Abudayyeh, JS Gootenberg, P Essletzbichler, S Han, J Joung, ... Nature 550 (7675), 280-284, 2017 | 2037 | 2017 |
| RNA editing with CRISPR-Cas13 DBT Cox, JS Gootenberg, OO Abudayyeh, B Franklin, MJ Kellner, J Joung, ... Science 358 (6366), 1019-1027, 2017 | 1914 | 2017 |
| Discovery and functional characterization of diverse class 2 CRISPR-Cas systems S Shmakov, OO Abudayyeh, KS Makarova, YI Wolf, JS Gootenberg, ... Molecular cell 60 (3), 385-397, 2015 | 1475 | 2015 |
| Field-deployable viral diagnostics using CRISPR-Cas13 C Myhrvold, CA Freije, JS Gootenberg, OO Abudayyeh, HC Metsky, ... Science 360 (6387), 444-448, 2018 | 1300 | 2018 |
| SHERLOCK: nucleic acid detection with CRISPR nucleases MJ Kellner, JG Koob, JS Gootenberg, OO Abudayyeh, F Zhang Nature protocols 14 (10), 2986-3012, 2019 | 1299 | 2019 |
| Genome-scale CRISPR-Cas9 knockout and transcriptional activation screening J Joung, S Konermann, JS Gootenberg, OO Abudayyeh, RJ Platt, ... Nature protocols 12 (4), 828-863, 2017 | 1281 | 2017 |
| Diversity and evolution of class 2 CRISPR–Cas systems S Shmakov, A Smargon, D Scott, D Cox, N Pyzocha, W Yan, ... Nature reviews microbiology 15 (3), 169-182, 2017 | 1176 | 2017 |
| Engineered CRISPR-Cas9 nuclease with expanded targeting space H Nishimasu, X Shi, S Ishiguro, L Gao, S Hirano, S Okazaki, T Noda, ... Science 361 (6408), 1259-1262, 2018 | 1118 | 2018 |
| Multiplex gene editing by CRISPR–Cpf1 using a single crRNA array B Zetsche, M Heidenreich, P Mohanraju, I Fedorova, J Kneppers, ... Nature biotechnology 35 (1), 31-34, 2017 | 999 | 2017 |
| CRISPR-based diagnostics MM Kaminski, OO Abudayyeh, JS Gootenberg, F Zhang, JJ Collins Nature biomedical engineering 5 (7), 643-656, 2021 | 832 | 2021 |
| Detection of SARS-CoV-2 with SHERLOCK one-pot testing J Joung, A Ladha, M Saito, NG Kim, AE Woolley, M Segel, RPJ Barretto, ... New England Journal of Medicine 383 (15), 1492-1494, 2020 | 716 | 2020 |
| Cas13b is a type VI-B CRISPR-associated RNA-guided RNase differentially regulated by accessory proteins Csx27 and Csx28 AA Smargon, DBT Cox, NK Pyzocha, K Zheng, IM Slaymaker, ... Molecular cell 65 (4), 618-630. e7, 2017 | 641 | 2017 |
| Clinical validation of a Cas13-based assay for the detection of SARS-CoV-2 RNA M Patchsung, K Jantarug, A Pattama, K Aphicho, S Suraritdechachai, ... Nature biomedical engineering 4 (12), 1140-1149, 2020 | 571 | 2020 |
| A melanoma cell state distinction influences sensitivity to MAPK pathway inhibitors DJ Konieczkowski, CM Johannessen, O Abudayyeh, JW Kim, ZA Cooper, ... Cancer discovery 4 (7), 816-827, 2014 | 556 | 2014 |
| CRISPR enzymes and systems F Zhang, B Zetsche, I Slaymaker, J Gootenberg, OO Abudayyeh US Patent 9,790,490, 2017 | 505 | 2017 |
Jonathan S. GootenbergMember of the Faculty, Harvard Medical Schoolmit.edu의 이메일 확인됨