| GQ-16, a novel peroxisome proliferator-activated receptor γ (PPARγ) ligand, promotes insulin sensitization without weight gain AA Amato, S Rajagopalan, JZ Lin, BM Carvalho, ACM Figueira, J Lu, ... Journal of Biological Chemistry 287 (33), 28169-28179, 2012 | 146 | 2012 |
| Structural rearrangements in the thyroid hormone receptor hinge domain and their putative role in the receptor function AS Nascimento, SMG Dias, FM Nunes, R Aparício, ALB Ambrosio, ... Journal of molecular biology 360 (3), 586-598, 2006 | 136 | 2006 |
| Gaining ligand selectivity in thyroid hormone receptors via entropy L Martínez, AS Nascimento, FM Nunes, K Phillips, R Aparicio, SMG Dias, ... Proceedings of the National Academy of Sciences 106 (49), 20717-20722, 2009 | 102 | 2009 |
| Protein structure modification and allergenic properties of whey proteins upon interaction with tea and coffee phenolic compounds TB Pessato, FPR de Morais, NC de Carvalho, ACM Figueira, ... Journal of Functional Foods 51, 121-129, 2018 | 92 | 2018 |
| Structural insights into human peroxisome proliferator activated receptor delta (PPAR-delta) selective ligand binding FAH Batista, DBB Trivella, A Bernardes, J Gratieri, PSL Oliveira, ... PloS one 7 (5), e33643, 2012 | 83 | 2012 |
| Signaling through retinoic acid receptors in cardiac development: Doing the right things at the right times J Xavier-Neto, ÂMS Costa, ACM Figueira, CD Caiaffa, FN do Amaral, ... Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1849 (2), 94-111, 2015 | 65 | 2015 |
| Multifactorial basis and therapeutic strategies in metabolism-related diseases JVS Guerra, MMG Dias, AJVC Brilhante, MF Terra, M Garcia-Arevalo, ... Nutrients 13 (8), 2830, 2021 | 64 | 2021 |
| Structural basis of GC-1 selectivity for thyroid hormone receptor isoforms L Bleicher, R Aparicio, FM Nunes, L Martinez, SM Gomes Dias, ... BMC structural biology 8, 1-13, 2008 | 64 | 2008 |
| Analysis of agonist and antagonist effects on thyroid hormone receptor conformation by hydrogen/deuterium exchange ACM Figueira, DM Saidemberg, PCT Souza, L Martínez, TS Scanlan, ... Molecular Endocrinology 25 (1), 15-31, 2011 | 60 | 2011 |
| Inflammatory reaction after aflibercept intravitreal injections associated with silicone oil droplets released from syringes: a case-control study GB Melo, ACM Figueira, FAH Batista, AASL Filho, EB Rodrigues, ... Ophthalmic Surgery, Lasers and Imaging Retina 50 (5), 288-294, 2019 | 53 | 2019 |
| Deciphering the role of the ADAM17-dependent secretome in cell signaling R Kawahara, RN Lima, RR Domingues, BA Pauletti, GV Meirelles, ... Journal of proteome research 13 (4), 2080-2093, 2014 | 50 | 2014 |
| Mapping the Intramolecular Vibrational Energy Flow in Proteins Reveals Functionally Important Residues L Martínez, ACM Figueira, P Webb, I Polikarpov, MS Skaf The Journal of Physical Chemistry Letters, 0 | 48 | |
| Identification of a new hormone-binding site on the surface of thyroid hormone receptor PCT Souza, AC Puhl, L Martínez, R Aparício, AS Nascimento, ... Molecular endocrinology 28 (4), 534-545, 2014 | 47 | 2014 |
| Release of silicone oil droplets from syringes GB Melo, CS Dias Junior, MR Carvalho, AL Cardoso, FB Morais, ... International Journal of Retina and Vitreous 5, 1-6, 2019 | 46 | 2019 |
| Structural dynamics of SARS-CoV-2 nucleocapsid protein induced by RNA binding HV Ribeiro-Filho, GE Jara, FAH Batista, GR Schleder, CC Costa Tonoli, ... PLOS Computational Biology 18 (5), e1010121, 2022 | 34 | 2022 |
| Screening for PPAR non-agonist ligands followed by characterization of a hit, AM-879, with additional no-adipogenic and cdk5-mediated phosphorylation inhibition properties HV Ribeiro Filho, N Bernardi Videira, AV Bridi, TH Tittanegro, ... Frontiers in endocrinology 9, 11, 2018 | 33 | 2018 |
| Structure-based identification of novel PPAR gamma ligands FMC da Silva, JC dos Santos, JLO Campos, AC Mafud, I Polikarpov, ... Bioorganic & medicinal chemistry letters 23 (21), 5795-5802, 2013 | 32 | 2013 |
| Low-resolution molecular models reveal the oligomeric state of the PPAR and the conformational organization of its domains in solution A Bernardes, FAH Batista, M de Oliveira Neto, ACM Figueira, P Webb, ... PloS one 7 (2), e31852, 2012 | 28 | 2012 |
| SN-38, the active metabolite of irinotecan, inhibits the acute inflammatory response by targeting toll-like receptor 4 DVT Wong, HV Ribeiro-Filho, CWS Wanderley, CAVG Leite, JB Lima, ... Cancer Chemotherapy and Pharmacology 84, 287-298, 2019 | 26 | 2019 |
| RXR Agonist Modulates TR: Corepressor Dissociation Upon 9-cis Retinoic Acid Treatment J Fattori, JLO Campos, TR Doratioto, LM Assis, MT Vitorino, I Polikarpov, ... Molecular Endocrinology 29 (2), 258-273, 2015 | 26 | 2015 |
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