| Pharmacologic inhibition of histone demethylation as a therapy for pediatric brainstem glioma R Hashizume, N Andor, Y Ihara, R Lerner, H Gan, X Chen, D Fang, ... Nature medicine 20 (12), 1394-1396, 2014 | 494 | 2014 |
| Targeting potassium channels in cancer X Huang, LY Jan Journal of Cell Biology 206 (2), 151-162, 2014 | 387 | 2014 |
| Divergent clonal selection dominates medulloblastoma at recurrence AS Morrissy, L Garzia, DJH Shih, S Zuyderduyn, X Huang, P Skowron, ... Nature 529 (7586), 351-357, 2016 | 360 | 2016 |
| A feedforward mechanism mediated by mechanosensitive ion channel PIEZO1 and tissue mechanics promotes glioma aggression X Chen, S Wanggou, A Bodalia, M Zhu, W Dong, JJ Fan, WC Yin, HK Min, ... Neuron 100 (4), 799-815. e7, 2018 | 332 | 2018 |
| ASCL1 reorganizes chromatin to direct neuronal fate and suppress tumorigenicity of glioblastoma stem cells NI Park, P Guilhamon, K Desai, RF McAdam, E Langille, M O’Connor, ... Cell stem cell 21 (2), 209-224. e7, 2017 | 238 | 2017 |
| A metabolic function of FGFR3-TACC3 gene fusions in cancer V Frattini, SM Pagnotta, Tala, JJ Fan, MV Russo, SB Lee, L Garofano, ... Nature 553 (7687), 222-227, 2018 | 186 | 2018 |
| Transventricular delivery of Sonic hedgehog is essential to cerebellar ventricular zone development X Huang, J Liu, T Ketova, JT Fleming, VK Grover, MK Cooper, ... Proceedings of the National Academy of Sciences 107 (18), 8422-8427, 2010 | 185 | 2010 |
| Recurrent noncoding U1 snRNA mutations drive cryptic splicing in SHH medulloblastoma H Suzuki, SA Kumar, S Shuai, A Diaz-Navarro, A Gutierrez-Fernandez, ... Nature 574 (7780), 707-711, 2019 | 176 | 2019 |
| Effects of tumor metabolic microenvironment on regulatory T cells Y Wang, XL Li, YZ Mo, CM Fan, L Tang, F Xiong, C Guo, B Xiang, M Zhou, ... Molecular cancer 17, 1-15, 2018 | 154 | 2018 |
| PINK1 is a negative regulator of growth and the Warburg effect in glioblastoma S Agnihotri, B Golbourn, X Huang, M Remke, S Younger, RA Cairns, ... Cancer research 76 (16), 4708-4719, 2016 | 134 | 2016 |
| Failure of human rhombic lip differentiation underlies medulloblastoma formation LD Hendrikse, P Haldipur, O Saulnier, J Millman, AH Sjoboen, ... Nature 609 (7929), 1021-1028, 2022 | 112 | 2022 |
| Sonic hedgehog signaling regulates a novel epithelial progenitor domain of the hindbrain choroid plexus X Huang, T Ketova, JT Fleming, H Wang, SK Dey, Y Litingtung, C Chiang Oxford University Press for The Company of Biologists Limited 136 (15), 2535 …, 2009 | 101 | 2009 |
| Voltage-gated potassium channel EAG2 controls mitotic entry and tumor growth in medulloblastoma via regulating cell volume dynamics X Huang, AM Dubuc, R Hashizume, J Berg, Y He, J Wang, C Chiang, ... Genes & development 26 (16), 1780-1796, 2012 | 99 | 2012 |
| EAG2 potassium channel with evolutionarily conserved function as a brain tumor target X Huang, Y He, AM Dubuc, R Hashizume, W Zhang, J Reimand, H Yang, ... Nature neuroscience 18 (9), 1236-1246, 2015 | 93 | 2015 |
| Microrobotic swarms for selective embolization J Law, X Wang, M Luo, L Xin, X Du, W Dou, T Wang, G Shan, Y Wang, ... Science Advances 8 (29), eabm5752, 2022 | 83 | 2022 |
| Conductive and elastic bottlebrush elastomers for ultrasoft electronics P Xu, S Wang, A Lin, HK Min, Z Zhou, W Dou, Y Sun, X Huang, H Tran, ... Nature Communications 14 (1), 623, 2023 | 75 | 2023 |
| Region-specific requirement for cholesterol modification of sonic hedgehog in patterning the telencephalon and spinal cord X Huang, Y Litingtung, C Chiang Oxford University Press for The Company of Biologists Limited 134 (11), 2095 …, 2007 | 65 | 2007 |
| Regulation of axon regeneration by the RNA repair and splicing pathway Y Song, D Sretavan, EA Salegio, J Berg, X Huang, T Cheng, X Xiong, ... Nature neuroscience 18 (6), 817-825, 2015 | 62 | 2015 |
| Gli3‐deficient mice exhibit cleft palate associated with abnormal tongue development X Huang, SL Goudy, T Ketova, Y Litingtung, C Chiang Developmental Dynamics 237 (10), 3079-3087, 2008 | 52 | 2008 |
| Ectopic sonic hedgehog signaling impairs telencephalic dorsal midline development: implication for human holoprosencephaly X Huang, Y Litingtung, C Chiang Human molecular genetics 16 (12), 1454-1468, 2007 | 52 | 2007 |
Xin ChenPrincipal investigator, Shanghai Jiao Tong University School of Medicineshsmu.edu.cn의 이메일 확인됨