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Brian O'Rourke
Brian O'Rourke
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Mitochondrial ATP-dependent potassium channels: novel effectors of cardioprotection?
Y Liu, T Sato, B O’Rourke, E Marban
Circulation 97 (24), 2463-2469, 1998
10571998
Nitric oxide regulates the heart by spatial confinement of nitric oxide synthase isoforms
LA Barouch, RW Harrison, MW Skaf, GO Rosas, TP Cappola, ZA Kobeissi, ...
Nature 416 (6878), 337-339, 2002
9802002
Sudden cardiac death prediction and prevention: report from a National Heart, Lung, and Blood Institute and Heart Rhythm Society Workshop
GI Fishman, SS Chugh, JP DiMarco, CM Albert, ME Anderson, RO Bonow, ...
Circulation 122 (22), 2335-2348, 2010
8122010
Ionic mechanism of action potential prolongation in ventricular myocytes from dogs with pacing-induced heart failure
S Kääb, HB Nuss, N Chiamvimonvat, B O’Rourke, PH Pak, DA Kass, ...
Circulation research 78 (2), 262-273, 1996
7311996
Mechanisms of altered excitation-contraction coupling in canine tachycardia-induced heart failure, II: model studies
RL Winslow, J Rice, S Jafri, E Marban, B O’Rourke
Circulation research 84 (5), 571-586, 1999
6671999
Mechanisms of altered excitation-contraction coupling in canine tachycardia-induced heart failure, I: experimental studies
B O’Rourke, DA Kass, GF Tomaselli, S Kääb, R Tunin, E Marbán
Circulation research 84 (5), 562-570, 1999
6031999
Synchronized whole cell oscillations in mitochondrial metabolism triggered by a local release of reactive oxygen species in cardiac myocytes
MA Aon, S Cortassa, E Marbán, B O'Rourke
Journal of Biological Chemistry 278 (45), 44735-44744, 2003
6002003
Cytoprotective role of Ca2+-activated K+ channels in the cardiac inner mitochondrial membrane
W Xu, Y Liu, S Wang, T McDonald, JE Van Eyk, A Sidor, B O'Rourke
Science 298 (5595), 1029-1033, 2002
5992002
Evidence for Mitochondrial K+ Channels and Their Role in Cardioprotection
B O’Rourke
Circulation research 94 (4), 420-432, 2004
5742004
Nitric oxide regulates exocytosis by S-nitrosylation of N-ethylmaleimide-sensitive factor
K Matsushita, CN Morrell, B Cambien, SX Yang, M Yamakuchi, C Bao, ...
Cell 115 (2), 139-150, 2003
5272003
Myocardial KATP Channels in Preconditioning
B O’Rourke
Circulation research 87 (10), 845-855, 2000
5102000
Mitochondrial ATP-Sensitive Potassium Channels Attenuate Matrix Ca2+ Overload During Simulated Ischemia and Reperfusion: Possible Mechanism of …
M Murata, M Akao, B O’Rourke, E Marbán
Circulation research 89 (10), 891-898, 2001
5092001
An integrated model of cardiac mitochondrial energy metabolism and calcium dynamics
S Cortassa, MA Aon, E Marbán, RL Winslow, B O’Rourke
Biophysical journal 84 (4), 2734-2755, 2003
5022003
Activation of mitochondrial ATP-dependent potassium channels by nitric oxide
N Sasaki, T Sato, A Ohler, B O’Rourke, E Marbán
Circulation 101 (4), 439-445, 2000
4772000
Modulation of Mitochondrial ATP-Dependent K+ Channels by Protein Kinase C
T Sato, B O’Rourke, E Marbán
Circulation Research 83 (1), 110-114, 1998
4651998
Elevated Cytosolic Na+ Decreases Mitochondrial Ca2+ Uptake During Excitation-Contraction Coupling and Impairs Energetic Adaptation in Cardiac Myocytes
C Maack, S Cortassa, MA Aon, AN Ganesan, T Liu, B O’Rourke
Circulation research 99 (2), 172-182, 2006
4392006
Redox-optimized ROS balance: a unifying hypothesis
MA Aon, S Cortassa, B O'rourke
Biochimica et Biophysica Acta (BBA)-Bioenergetics 1797 (6-7), 865-877, 2010
4342010
Mitochondrial ATP-sensitive potassium channels inhibit apoptosis induced by oxidative stress in cardiac cells
M Akao, A Ohler, B O’Rourke, E Marbán
Circulation Research 88 (12), 1267-1275, 2001
4212001
The mitochondrial origin of postischemic arrhythmias
FG Akar, MA Aon, GF Tomaselli, B O’Rourke
The Journal of clinical investigation 115 (12), 3527-3535, 2005
4152005
Mitochondrial ion channels
B O’Rourke
Annu. Rev. Physiol. 69 (1), 19-49, 2007
3782007
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