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Lina Leon
Lina Leon
CRISPR-Cas genome engineer, Scientist
ucsf.edu의 이메일 확인됨 - 홈페이지
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Discovery of widespread type I and type V CRISPR-Cas inhibitors
ND Marino, JY Zhang, AL Borges, AA Sousa, LM Leon, BJ Rauch, ...
Science 362 (6411), 240-242, 2018
2582018
A bacteriophage nucleus-like compartment shields DNA from CRISPR nucleases
SD Mendoza, ES Nieweglowska, S Govindarajan, LM Leon, JD Berry, ...
Nature 577 (7789), 244-248, 2020
1842020
A compact Cascade–Cas3 system for targeted genome engineering
B Csörgő, LM León, IJ Chau-Ly, A Vasquez-Rifo, JD Berry, C Mahendra, ...
Nature methods 17 (12), 1183-1190, 2020
1592020
Mobile element warfare via CRISPR and anti-CRISPR in Pseudomonas aeruginosa
LM Leon, AE Park, AL Borges, JY Zhang, J Bondy-Denomy
Nucleic acids research 49 (4), 2114-2125, 2021
712021
How bacteria control the CRISPR-Cas arsenal
LM Leon, SD Mendoza, J Bondy-Denomy
Current opinion in microbiology 42, 87-95, 2018
402018
A nucleus-like compartment shields bacteriophage DNA from CRISPR-Cas and restriction nucleases
SD Mendoza, JD Berry, ES Nieweglowska, LM Leon, DA Agard, ...
BioRxiv, 370791, 2018
102018
No 主観的健康感を中心とした在宅高齢者における 健康関連指標に関する共分散構造分析 Title
SD Mendoza, ES Nieweglowska, S Govindarajan, LM Leon, JD Berry, ...
Nat. Microbiol 3 (1), 641, 2020
92020
A minimal CRISPR-Cas3 system for genome engineering
B Csörgő, LM León, IJ Chau-Ly, A Vasquez-Rifo, JD Berry, C Mahendra, ...
bioRxiv, 860999, 2019
32019
CRISPR-Cas3: Studying the molecular interactions that drive adaptation & engineering novel bacterial editing tools
LM Leon
University of California, San Francisco, 2021
12021
334 Computational mapping of CAR-T cell exhaustion through single-cell perturbation screens
L Wang, D DeTomaso, A Cass, J Chow, R Bao, AC Boroughs, A Cardozo, ...
Journal for ImmunoTherapy of Cancer 12 (Suppl 2), 2024
2024
282 Improving solid tumor CAR-T therapies by modulating T cell transcriptional states using combinatorial in vitro CRISPR screening followed by in vivo validation
LM Leon, AC Boroughs, A Cass, J Choe, A Cardozo, J Chow, ...
Journal for ImmunoTherapy of Cancer 12 (Suppl 2), 2024
2024
Crispr-cas3 for making genomic deletions and inducing recombination
LM Leon, B Csorgo, J Bondy-Denomy
US Patent App. 17/621,669, 2022
2022
A minimal CRISPR-Cas3 system for genome engineering [preprint]
B Csörgő, LM León, IJ Chau-Ly, A Vasquez-Rifo, JD Berry, C Mahendra, ...
2019
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