MeCP2, a key contributor to neurological disease, activates and represses transcription M Chahrour, SY Jung, C Shaw, X Zhou, STC Wong, J Qin, HY Zoghbi Science 320 (5880), 1224-1229, 2008 | 2040 | 2008 |
SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity E Jacinto, V Facchinetti, D Liu, N Soto, S Wei, SY Jung, Q Huang, J Qin, ... Cell 127 (1), 125-137, 2006 | 1798 | 2006 |
Negative regulation of the deacetylase SIRT1 by DBC1 W Zhao, JP Kruse, Y Tang, SY Jung, J Qin, W Gu Nature 451 (7178), 587-590, 2008 | 578 | 2008 |
Nanog and Oct4 associate with unique transcriptional repression complexes in embryonic stem cells J Liang, M Wan, Y Zhang, P Gu, H Xin, SY Jung, J Qin, J Wong, ... Nature cell biology 10 (6), 731-739, 2008 | 553 | 2008 |
The spliceosome is a therapeutic vulnerability in MYC-driven cancer TYT Hsu, LM Simon, NJ Neill, R Marcotte, A Sayad, CS Bland, ... Nature 525 (7569), 384-388, 2015 | 508 | 2015 |
Analysis of the human endogenous coregulator complexome A Malovannaya, RB Lanz, SY Jung, Y Bulynko, NT Le, DW Chan, C Ding, ... Cell 145 (5), 787-799, 2011 | 496 | 2011 |
Acetylation of Smc3 by Eco1 is required for S phase sister chromatid cohesion in both human and yeast J Zhang, X Shi, Y Li, BJ Kim, J Jia, Z Huang, T Yang, X Fu, SY Jung, ... Molecular cell 31 (1), 143-151, 2008 | 483 | 2008 |
ATR phosphorylates SMARCAL1 to prevent replication fork collapse FB Couch, CE Bansbach, R Driscoll, JW Luzwick, GG Glick, R Bétous, ... Genes & development 27 (14), 1610-1623, 2013 | 473 | 2013 |
DDX1, DDX21, and DHX36 helicases form a complex with the adaptor molecule TRIF to sense dsRNA in dendritic cells Z Zhang, T Kim, M Bao, V Facchinetti, SY Jung, AA Ghaffari, J Qin, ... Immunity 34 (6), 866-878, 2011 | 427 | 2011 |
The SRC-3/AIB1 coactivator is degraded in a ubiquitin-and ATP-independent manner by the REGγ proteasome X Li, DM Lonard, SY Jung, A Malovannaya, Q Feng, J Qin, SY Tsai, ... Cell 124 (2), 381-392, 2006 | 328 | 2006 |
Trim24 targets endogenous p53 for degradation K Allton, AK Jain, HM Herz, WW Tsai, SY Jung, J Qin, A Bergmann, ... Proceedings of the National Academy of Sciences 106 (28), 11612-11616, 2009 | 315 | 2009 |
Acetylation on histone H3 lysine 9 mediates a switch from transcription initiation to elongation LA Gates, J Shi, AD Rohira, Q Feng, B Zhu, MT Bedford, CA Sagum, ... Journal of Biological Chemistry 292 (35), 14456-14472, 2017 | 258 | 2017 |
A proteomic landscape of diffuse-type gastric cancer S Ge, X Xia, C Ding, B Zhen, Q Zhou, J Feng, J Yuan, R Chen, Y Li, Z Ge, ... Nature communications 9 (1), 1012, 2018 | 254 | 2018 |
A proteomic analysis of ataxia telangiectasia-mutated (ATM)/ATM-Rad3-related (ATR) substrates identifies the ubiquitin-proteasome system as a regulator for DNA damage checkpoints JJ Mu, Y Wang, H Luo, M Leng, J Zhang, T Yang, D Besusso, SY Jung, ... Journal of Biological Chemistry 282 (24), 17330-17334, 2007 | 211 | 2007 |
Metabolic enzyme PFKFB4 activates transcriptional coactivator SRC-3 to drive breast cancer S Dasgupta, K Rajapakshe, B Zhu, BC Nikolai, P Yi, N Putluri, JM Choi, ... Nature 556 (7700), 249-254, 2018 | 208 | 2018 |
Tipping the immunostimulatory and inhibitory DAMP balance to harness immunogenic cell death K Hayashi, F Nikolos, YC Lee, A Jain, E Tsouko, H Gao, A Kasabyan, ... Nature communications 11 (1), 6299, 2020 | 205 | 2020 |
Enhancer RNA m6A methylation facilitates transcriptional condensate formation and gene activation JH Lee, R Wang, F Xiong, J Krakowiak, Z Liao, PT Nguyen, ... Molecular cell 81 (16), 3368-3385. e9, 2021 | 202 | 2021 |
Acetylation disfavors tau phase separation JC Ferreon, A Jain, KJ Choi, PS Tsoi, KR MacKenzie, SY Jung, ... International journal of molecular sciences 19 (5), 1360, 2018 | 167 | 2018 |
Hepatitis B virus regulatory HBx protein binds to adaptor protein IPS-1 and inhibits the activation of beta interferon M Kumar, SY Jung, AJ Hodgson, CR Madden, J Qin, BL Slagle Journal of virology 85 (2), 987-995, 2011 | 164 | 2011 |
A new isoform of steroid receptor coactivator-1 is crucial for pathogenic progression of endometriosis SJ Han, SM Hawkins, K Begum, SY Jung, E Kovanci, J Qin, JP Lydon, ... Nature medicine 18 (7), 1102-1111, 2012 | 159 | 2012 |