Arachidonic and eicosapentaenoic acid metabolism by human CYP1A1: highly stereoselective formation of 17(R),18(S)-epoxyeicosatetraenoic acid D Schwarz, P Kisselev, SS Ericksen, GD Szklarz, A Chernogolov, ... Biochemical pharmacology 67 (8), 1445-1457, 2004 | 167 | 2004 |
A marine microbiome antifungal targets urgent-threat drug-resistant fungi F Zhang, M Zhao, DR Braun, SS Ericksen, JS Piotrowski, J Nelson, ... Science 370 (6519), 974-978, 2020 | 159 | 2020 |
Machine Learning Consensus Scoring Improves Performance Across Targets in Structure-Based Virtual Screening SS Ericksen, H Wu, H Zhang, LA Michael, MA Newton, FM Hoffmann, ... Journal of Chemical Information and Modeling, 2017 | 106 | 2017 |
The effect of reciprocal active site mutations in human cytochromes P450 1A1 and 1A2 on alkoxyresorufin metabolism J Liu, SS Ericksen, M Sivaneri, D Besspiata, CW Fisher, GD Szklarz Archives of Biochemistry and Biophysics 424 (1), 33-43, 2004 | 84 | 2004 |
Structural determinants for high-affinity zolpidem binding to GABA-A receptors F Sancar, SS Ericksen, AM Kucken, JA Teissere, C Czajkowski Molecular pharmacology 71 (1), 38-46, 2007 | 78 | 2007 |
Practical model selection for prospective virtual screening S Liu, M Alnammi, SS Ericksen, AF Voter, GE Ananiev, JL Keck, ... Journal of chemical information and modeling 59 (1), 282-293, 2018 | 76 | 2018 |
Characterization of substrate binding to cytochrome P450 1A1 using molecular modeling and kinetic analyses: case of residue 382 J Liu, SS Ericksen, D Besspiata, CW Fisher, GD Szklarz Drug metabolism and Disposition 31 (4), 412-420, 2003 | 60 | 2003 |
In silico modeling and scoring of PROTAC-mediated ternary complex poses J Liao, X Nie, IC Unarta, SS Ericksen, W Tang Journal of Medicinal Chemistry 65 (8), 6116-6132, 2022 | 51 | 2022 |
Oxidative stress via inhibition of the mitochondrial electron transport and Nrf-2-mediated anti-oxidative response regulate the cytotoxic activity of plumbagin A Kapur, T Beres, K Rathi, AP Nayak, A Czarnecki, M Felder, A Gillette, ... Scientific Reports 8 (1), 1073, 2018 | 39 | 2018 |
Ligand selectivity of D2 dopamine receptors is modulated by changes in local dynamics produced by sodium binding SS Ericksen, DF Cummings, H Weinstein, JA Schetz Journal of Pharmacology and Experimental Therapeutics 328 (1), 40-54, 2009 | 38 | 2009 |
DBSI: DNA-Binding Site Identifier X Zhu, SS Ericksen, JC Mitchell Nucleic Acids Research 41 (16), e160, 2013 | 34 | 2013 |
Atovaquone: an inhibitor of oxidative phosphorylation as studied in gynecologic cancers A Kapur, P Mehta, AD Simmons, SS Ericksen, G Mehta, SP Palecek, ... Cancers 14 (9), 2297, 2022 | 30 | 2022 |
Tandem couture: Cys-loop receptor concatamer insights and caveats SS Ericksen, AJ Boileau Molecular neurobiology 35, 113-127, 2007 | 27 | 2007 |
Preferred binding orientations of phenacetin in CYP1A1 and CYP1A2 are associated with isoform-selective metabolism Q Huang, RS Deshmukh, SS Ericksen, Y Tu, GD Szklarz Drug Metabolism and Disposition 40 (12), 2324-2331, 2012 | 26 | 2012 |
Transmembrane segment five serines of the D4 dopamine receptor uniquely influence the interactions of dopamine, norepinephrine, and Ro10-4548 DF Cummings, SS Ericksen, A Goetz, JA Schetz Journal of Pharmacology and Experimental Therapeutics 333 (3), 682-695, 2010 | 25 | 2010 |
Regiospecificity of human cytochrome P450 1A1-mediated oxidations: the role of steric effects SS Ericksen, GD Szklarz Journal of Biomolecular Structure and Dynamics 23 (3), 243-256, 2005 | 23 | 2005 |
Structural basis of dopamine receptor activation IS Moreira, L Shi, Z Freyberg, SS Ericksen, H Weinstein, JA Javitch The dopamine receptors, 47-73, 2010 | 16 | 2010 |
Predicting kinase inhibitors using bioactivity matrix derived informer sets H Zhang, SS Ericksen, C Lee, GE Ananiev, N Wlodarchak, P Yu, ... PLoS computational biology 15 (8), e1006813, 2019 | 12 | 2019 |
Evaluating scalable supervised learning for synthesize-on-demand chemical libraries M Alnammi, S Liu, SS Ericksen, GE Ananiev, AF Voter, S Guo, JL Keck, ... Journal of Chemical Information and Modeling 63 (17), 5513-5528, 2023 | 11 | 2023 |
DBSI server: DNA binding site identifier S Sukumar, Z Zhu, SS Ericksen, JC Mitchell Bioinformatics 32 (18), 2853-2855, 2016 | 11 | 2016 |