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Tomohiro ICHITSUKA
Tomohiro ICHITSUKA
National Insitute of Advanced Industrial Science and Technology
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Nickel-Catalyzed Allylic C(sp3)–F Bond Activation of Trifluoromethyl Groups via β-Fluorine Elimination: Synthesis of Difluoro-1,4-dienes
T Ichitsuka, T Fujita, J Ichikawa
ACS Catalysis 5 (10), 5947-5950, 2015
1862015
Flow fine synthesis with heterogeneous catalysts
K Masuda, T Ichitsuka, N Koumura, K Sato, S Kobayashi
Tetrahedron 74 (15), 1705-1730, 2018
1822018
Double C F Bond Activation through β‐Fluorine Elimination: Nickel‐Mediated [3+ 2] Cycloaddition of 2‐Trifluoromethyl‐1‐alkenes with Alkynes
T Ichitsuka, T Fujita, T Arita, J Ichikawa
Angewandte Chemie International Edition 53 (29), 7564-7568, 2014
1622014
Design and synthesis of aromatics through [2+ 2+ 2] cyclotrimerization
S Kotha, K Lahiri, G Sreevani
Synlett 29 (18), 2342-2361, 2018
492018
A versatile difluorovinylation method: Cross-coupling reactions of the 2, 2-difluorovinylzinc–TMEDA complex with alkenyl, alkynyl, allyl, and benzyl halides
T Ichitsuka, T Takanohashi, T Fujita, J Ichikawa
Journal of Fluorine Chemistry 170, 29-37, 2015
442015
Platform for ring-fluorinated benzoheterole derivatives: palladium-catalyzed regioselective 1, 1-difluoroallylation and heck cyclization
T Fujita, K Sugiyama, S Sanada, T Ichitsuka, J Ichikawa
Organic letters 18 (2), 248-251, 2016
432016
Catalytic defluorinative [3+ 2] cycloaddition of trifluoromethylalkenes with alkynes via reduction of nickel (II) fluoride species
T Fujita, T Arita, T Ichitsuka, J Ichikawa
Dalton transactions 44 (45), 19460-19463, 2015
412015
Facile Synthesis of β, β-Difluorostyrenes via the Negishi Coupling of Thermally Stable 2, 2-Difluorovinyl Zinc–TMEDA Complex
T Fujita, T Ichitsuka, K Fuchibe, J Ichikawa
Chemistry Letters 40 (9), 986-988, 2011
352011
Ni‐Catalyzed Synthesis of Fluoroarenes via [2+ 2+ 2] Cycloaddition Involving α‐Fluorine Elimination
T Fujita, Y Watabe, T Ichitsuka, J Ichikawa
Chemistry–A European Journal 21 (38), 13225-13228, 2015
242015
Continuous synthesis of aryl amines from phenols utilizing integrated packed‐bed flow systems
T Ichitsuka, I Takahashi, N Koumura, K Sato, S Kobayashi
Angewandte Chemie 132 (37), 16025-16030, 2020
232020
Readily Available Immobilized Pd Catalysts for Suzuki‐Miyaura Coupling under Continuous‐flow Conditions
T Ichitsuka, N Suzuki, M Sairenji, N Koumura, S Onozawa, K Sato, ...
ChemCatChem 11 (10), 2427-2431, 2019
232019
Flash generation and borylation of 1-(trifluoromethyl) vinyllithium toward synthesis of α-(trifluoromethyl) styrenes
T Fujita, N Konno, Y Watabe, T Ichitsuka, A Nagaki, J Yoshida, J Ichikawa
Journal of fluorine chemistry 207, 72-76, 2018
212018
Nickel-Catalyzed Allylic C (sp 3)–F Bond Activation of Trifluoromethyl Groups via β-Fluorine Elimination: Synthesis of Difluoro-1, 4-dienes, ACS Catal., 2015, 5, 5947–5950 …
T Ichitsuka, T Fujita, J Ichikawa
J. Am. Chem. Soc 138, 12340-12343, 2016
21*2016
Zirconium Oxide‐Catalyzed Direct Amidation of Unactivated Esters under Continuous‐Flow Conditions
MN Rashed, K Masuda, T Ichitsuka, N Koumura, K Sato, S Kobayashi
Advanced Synthesis & Catalysis 363 (10), 2529-2535, 2021
182021
Aqueous Flow Hydroxycarbonylation of Aryl Halides Catalyzed by an Amphiphilic Polymer-Supported Palladium–Diphenylphosphine Catalyst
T Osako, R Kaiser, K Torii, Y Uozumi
Synlett 30 (08), 961-966, 2019
142019
Facile synthesis of unsymmetrical 1, 1-diaryl-2, 2-difluoroethenes via stepwise coupling of 1, 1-dibromo-2, 2-difluoroethenes
T Fujita, N Suzuki, T Ichitsuka, J Ichikawa
Journal of fluorine chemistry 155, 97-101, 2013
92013
Stereoretentive N‐Arylation of Amino Acid Esters with Cyclohexanones Utilizing a Continuous‐Flow System
T Ichitsuka, S Komatsuzaki, K Masuda, N Koumura, K Sato, S Kobayashi
Chemistry–A European Journal 27 (42), 10844-10848, 2021
72021
Telescoped two-step continuous-flow synthesis of vanillin
T Ichitsuka, M Sato, S Miura, T Makino, T Ishizaka
ACS Sustainable Chemistry & Engineering 11 (45), 16322-16329, 2023
62023
Nickel‐Catalyzed Reductive Allyl− Aryl Cross‐Electrophile Coupling via Allylic C− F Bond Activation
T Fujita, Y Kobayashi, I Takahashi, R Morioka, T Ichitsuka, J Ichikawa
Chemistry–A European Journal 28 (2), e202103643, 2022
52022
A continuous flow process for biaryls based on sequential Suzuki–Miyaura coupling and supercritical carbon dioxide extraction
T Ichitsuka, T Fujii, M Kobune, T Makino, S Kawasaki
Reaction Chemistry & Engineering 6 (12), 2248-2252, 2021
52021
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