Nickel-Catalyzed Allylic C(sp3)–F Bond Activation of Trifluoromethyl Groups via β-Fluorine Elimination: Synthesis of Difluoro-1,4-dienes T Ichitsuka, T Fujita, J Ichikawa ACS Catalysis 5 (10), 5947-5950, 2015 | 186 | 2015 |
Flow fine synthesis with heterogeneous catalysts K Masuda, T Ichitsuka, N Koumura, K Sato, S Kobayashi Tetrahedron 74 (15), 1705-1730, 2018 | 182 | 2018 |
Double C F Bond Activation through β‐Fluorine Elimination: Nickel‐Mediated [3+ 2] Cycloaddition of 2‐Trifluoromethyl‐1‐alkenes with Alkynes T Ichitsuka, T Fujita, T Arita, J Ichikawa Angewandte Chemie International Edition 53 (29), 7564-7568, 2014 | 162 | 2014 |
Design and synthesis of aromatics through [2+ 2+ 2] cyclotrimerization S Kotha, K Lahiri, G Sreevani Synlett 29 (18), 2342-2361, 2018 | 49 | 2018 |
A versatile difluorovinylation method: Cross-coupling reactions of the 2, 2-difluorovinylzinc–TMEDA complex with alkenyl, alkynyl, allyl, and benzyl halides T Ichitsuka, T Takanohashi, T Fujita, J Ichikawa Journal of Fluorine Chemistry 170, 29-37, 2015 | 44 | 2015 |
Platform for ring-fluorinated benzoheterole derivatives: palladium-catalyzed regioselective 1, 1-difluoroallylation and heck cyclization T Fujita, K Sugiyama, S Sanada, T Ichitsuka, J Ichikawa Organic letters 18 (2), 248-251, 2016 | 43 | 2016 |
Catalytic defluorinative [3+ 2] cycloaddition of trifluoromethylalkenes with alkynes via reduction of nickel (II) fluoride species T Fujita, T Arita, T Ichitsuka, J Ichikawa Dalton transactions 44 (45), 19460-19463, 2015 | 41 | 2015 |
Facile Synthesis of β, β-Difluorostyrenes via the Negishi Coupling of Thermally Stable 2, 2-Difluorovinyl Zinc–TMEDA Complex T Fujita, T Ichitsuka, K Fuchibe, J Ichikawa Chemistry Letters 40 (9), 986-988, 2011 | 35 | 2011 |
Ni‐Catalyzed Synthesis of Fluoroarenes via [2+ 2+ 2] Cycloaddition Involving α‐Fluorine Elimination T Fujita, Y Watabe, T Ichitsuka, J Ichikawa Chemistry–A European Journal 21 (38), 13225-13228, 2015 | 24 | 2015 |
Continuous synthesis of aryl amines from phenols utilizing integrated packed‐bed flow systems T Ichitsuka, I Takahashi, N Koumura, K Sato, S Kobayashi Angewandte Chemie 132 (37), 16025-16030, 2020 | 23 | 2020 |
Readily Available Immobilized Pd Catalysts for Suzuki‐Miyaura Coupling under Continuous‐flow Conditions T Ichitsuka, N Suzuki, M Sairenji, N Koumura, S Onozawa, K Sato, ... ChemCatChem 11 (10), 2427-2431, 2019 | 23 | 2019 |
Flash generation and borylation of 1-(trifluoromethyl) vinyllithium toward synthesis of α-(trifluoromethyl) styrenes T Fujita, N Konno, Y Watabe, T Ichitsuka, A Nagaki, J Yoshida, J Ichikawa Journal of fluorine chemistry 207, 72-76, 2018 | 21 | 2018 |
Nickel-Catalyzed Allylic C (sp 3)–F Bond Activation of Trifluoromethyl Groups via β-Fluorine Elimination: Synthesis of Difluoro-1, 4-dienes, ACS Catal., 2015, 5, 5947–5950 … T Ichitsuka, T Fujita, J Ichikawa J. Am. Chem. Soc 138, 12340-12343, 2016 | 21* | 2016 |
Zirconium Oxide‐Catalyzed Direct Amidation of Unactivated Esters under Continuous‐Flow Conditions MN Rashed, K Masuda, T Ichitsuka, N Koumura, K Sato, S Kobayashi Advanced Synthesis & Catalysis 363 (10), 2529-2535, 2021 | 18 | 2021 |
Aqueous Flow Hydroxycarbonylation of Aryl Halides Catalyzed by an Amphiphilic Polymer-Supported Palladium–Diphenylphosphine Catalyst T Osako, R Kaiser, K Torii, Y Uozumi Synlett 30 (08), 961-966, 2019 | 14 | 2019 |
Facile synthesis of unsymmetrical 1, 1-diaryl-2, 2-difluoroethenes via stepwise coupling of 1, 1-dibromo-2, 2-difluoroethenes T Fujita, N Suzuki, T Ichitsuka, J Ichikawa Journal of fluorine chemistry 155, 97-101, 2013 | 9 | 2013 |
Stereoretentive N‐Arylation of Amino Acid Esters with Cyclohexanones Utilizing a Continuous‐Flow System T Ichitsuka, S Komatsuzaki, K Masuda, N Koumura, K Sato, S Kobayashi Chemistry–A European Journal 27 (42), 10844-10848, 2021 | 7 | 2021 |
Telescoped two-step continuous-flow synthesis of vanillin T Ichitsuka, M Sato, S Miura, T Makino, T Ishizaka ACS Sustainable Chemistry & Engineering 11 (45), 16322-16329, 2023 | 6 | 2023 |
Nickel‐Catalyzed Reductive Allyl− Aryl Cross‐Electrophile Coupling via Allylic C− F Bond Activation T Fujita, Y Kobayashi, I Takahashi, R Morioka, T Ichitsuka, J Ichikawa Chemistry–A European Journal 28 (2), e202103643, 2022 | 5 | 2022 |
A continuous flow process for biaryls based on sequential Suzuki–Miyaura coupling and supercritical carbon dioxide extraction T Ichitsuka, T Fujii, M Kobune, T Makino, S Kawasaki Reaction Chemistry & Engineering 6 (12), 2248-2252, 2021 | 5 | 2021 |