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David Juan
David Juan
Spanish National Centre for Biotechnology
cnb.csic.es의 이메일 확인됨
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The allelic landscape of human blood cell trait variation and links to common complex disease
WJ Astle, H Elding, T Jiang, D Allen, D Ruklisa, AL Mann, D Mead, ...
Cell 167 (5), 1415-1429. e19, 2016
12712016
Multiple evidence strands suggest that there may be as few as 19 000 human protein-coding genes
I Ezkurdia, D Juan, JM Rodriguez, A Frankish, M Diekhans, J Harrow, ...
Human molecular genetics 23 (22), 5866-5878, 2014
8192014
Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms
DE Gordon, J Hiatt, M Bouhaddou, VV Rezelj, S Ulferts, H Braberg, ...
Science 370 (6521), eabe9403, 2020
6862020
Emerging methods in protein co-evolution
D De Juan, F Pazos, A Valencia
Nature Reviews Genetics 14 (4), 249-261, 2013
6732013
Spatiotemporal transcriptomic divergence across human and macaque brain development
Y Zhu, AMM Sousa, T Gao, M Skarica, M Li, G Santpere, ...
Science 362 (6420), eaat8077, 2018
3482018
A comparative genomics multitool for scientific discovery and conservation
Nature 587 (7833), 240-245, 2020
2972020
Identification of amino acid residues crucial for chemokine receptor dimerization
P Hernanz-Falcon, JM Rodríguez-Frade, A Serrano, D Juan, A Del Sol, ...
Nature immunology 5 (2), 216-223, 2004
2352004
High-confidence prediction of global interactomes based on genome-wide coevolutionary networks
D Juan, F Pazos, A Valencia
Proceedings of the National Academy of Sciences 105 (3), 934-939, 2008
2122008
Protein interactions and ligand binding: from protein subfamilies to functional specificity
A Rausell, D Juan, F Pazos, A Valencia
Proceedings of the National Academy of Sciences 107 (5), 1995-2000, 2010
1782010
Assessing protein co-evolution in the context of the tree of life assists in the prediction of the interactome
F Pazos, JAG Ranea, D Juan, MJE Sternberg
Journal of molecular biology 352 (4), 1002-1015, 2005
1652005
Evolutionary constraint and innovation across hundreds of placental mammals
MJ Christmas, IM Kaplow, DP Genereux, MX Dong, GM Hughes, X Li, ...
Science 380 (6643), eabn3943, 2023
1592023
Genome-wide analysis of differential transcriptional and epigenetic variability across human immune cell types
S Ecker, L Chen, V Pancaldi, FO Bagger, JM Fernández, ...
Genome biology 18, 1-17, 2017
1232017
A global catalog of whole-genome diversity from 233 primate species
LFK Kuderna, H Gao, MC Janiak, M Kuhlwilm, JD Orkin, T Bataillon, ...
Science 380 (6648), 906-913, 2023
1072023
Intronic CNVs and gene expression variation in human populations
M Rigau, D Juan, A Valencia, D Rico
PLoS Genetics 15 (1), e1007902, 2019
1012019
The landscape of tolerated genetic variation in humans and primates
H Gao, T Hamp, J Ede, JG Schraiber, J McRae, M Singer-Berk, Y Yang, ...
Science 380 (6648), eabn8153, 2023
1002023
Integrating gene annotation with orthology inference at scale
BM Kirilenko, C Munegowda, E Osipova, D Jebb, V Sharma, M Blumer, ...
Science 380 (6643), eabn3107, 2023
912023
Reconstructing Denisovan anatomy using DNA methylation maps
D Gokhman, N Mishol, M de Manuel, D de Juan, J Shuqrun, E Meshorer, ...
Cell 179 (1), 180-192. e10, 2019
862019
A genomic timescale for placental mammal evolution
NM Foley, VC Mason, AJ Harris, KR Bredemeyer, J Damas, HA Lewin, ...
Science 380 (6643), eabl8189, 2023
852023
Loose ends: almost one in five human genes still have unresolved coding status
F Abascal, D Juan, I Jungreis, L Martinez, M Rigau, JM Rodriguez, ...
Nucleic acids research 46 (14), 7070-7084, 2018
782018
Subfunctionalization via adaptive evolution influenced by genomic context: the case of histone chaperones ASF1a and ASF1b
F Abascal, A Corpet, ZA Gurard-Levin, D Juan, F Ochsenbein, D Rico, ...
Molecular biology and evolution 30 (8), 1853-1866, 2013
772013
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